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PROBING NAD(P)H AVAILABILITY IN LIVING CELLS USING MINIATURIZED ELECTROCHEMICAL SYSTEMS

The work presented in this thesis demonstrates the application of electrochemical methods for probing the dynamics of cellular metabolism in prokaryotic and eukaryotic cells. The main part of the work has been done using genetically modified strains of yeast. Employing baker’s yeast, S. cerevisiae, as a model organism, it was demonstrated how an amperometric method can be utilized for real-time in

Gender Differences in Environmental Impacts from Patterns of Transportation. A case study from Sweden

Addressing unsustainable consumption patterns is an important target for fulfilling the goals set in, among others, Agenda 21 and the United Nations Framework Convention on Climate Change. Gender differences in consumption patterns and their environmental impact have so far been poorly investigated. Gender differences in travelling patterns in Sweden are explored using data from the National Trav

Strategy for detection of prostate cancer based on relation between prostate specific antigen at age 40-55 and long term risk of metastasis: case-control study

Objective To determine the association between concentration of prostate specific antigen (PSA) at age 40-55 and subsequent risk of prostate cancer metastasis and mortality in an unscreened population to evaluate when to start screening for prostate cancer and whether rescreening could be risk stratified. Design Case-control study with 1: 3 matching nested within a highly representative population

Using narrative analysis to understand the combined use of complementary therapies and bio-medically oriented health care

Rather than using different therapies in isolation, many cancer patients use different therapies in a complementary fashion. Little research to date has given attention to individuals' experiences of the combined use of biomedically oriented health care (BHC) and complementary and alternative therapies (CATs). Therefore, this paper examines one individual's negotiation between complementary self-c

Wax esters produced by solvent-free energy-efficient enzymatic synthesis and their applicability as wood coatings

The study aimed at developing a process for making a wood coating wax based on the principles of green chemistry. The research was conducted within the Swedish interdisciplinary research programme Greenchem. Wax esters are attractive since they are non-hazardous, biodegradable and can be produced in an atom-efficient process from building blocks obtained from renewable resources. Four wax esters w

Time constraints on exhumation of the East African Orogen from field observations and Ar-40/Ar-39 cooling ages of low-angle mylonites in Eritrea, NE Africa

Neoproterozoic high-grade metamorphic rocks of the lower to middle crust are exposed along parts of the East African Orogen (EAO). However, the mechanisms and rates of exhumation of these deep orogenic rocks remain unclear. In eastern Eritrea, the rocks of the EAO comprise two lithotectonic domains: Ghedem and Bizen. The Ghedem domain consists of low-angle mylonites among lower to middle crustal g

On the history of supportive therapy

A short history of supportive therapy is delineated by the quadruple division in prehistory, definition, establishment and the phase of integration. Glimpses of the history of the development of the supportive concept are given. It is pointed out that the concept of supportive therapy is stemming from the awkward dichotomy from the ego-psychological paradigm in the psychoanalytic tradition: insigh

Development of a Novel Method for Evaluation of Interfacial Tension between Polymer Melts

A novel method for the evaluation of interfacial tension of high viscosity polymer melts is described. The method involves the tracking of the shape evolution of a highly deformed droplet of one material imbedded in a second one. This makes it possible to determine the interfacial tension over a relatively short time period. The imbedded material is initially either a fiber or a disk. The techniqu

Sourcing Decisions of Software Applications Hosting: What Influence has e-Government Services

There are a lot of reasons reported for why organisations start a sourcing decision. This chapter discusses this theme based on two questions: Does the need and/or wish to increase e-Government services influence the start of a sourcing decision process aiming at reorganising hosting of software applications and if it does, how does it influence the start of such a decision-making process? The poi

PIXE in 1980: Summary of the Second International Conference on Particle Induced X-Ray Emission and its Analytical Applications

The Second International Conference on Particle Induced X-ray Emission (PIXE) and its analytical applications was held in Lund, Sweden, June 9-12, 1980. About a hundred papers were presented, including seven invited talks (PIXE and particle scattering, microbeam analysis (2), applications to aerosols (2) and biological samples (2)). The main impression left by the conference was that both the PIXE

Latent Autoimmune Diabetes in Adults: Definition, Prevalence, {beta}-Cell Function, and Treatment.

Latent autoimmune diabetes in adults (LADA) is a disorder in which, despite the presence of islet antibodies at diagnosis of diabetes, the progression of autoimmune ß-cell failure is slow. LADA patients are therefore not insulin requiring, at least during the first 6 months after diagnosis of diabetes. Among patients with phenotypic type 2 diabetes, LADA occurs in 10% of individuals older than 35

Trade, Competition and Productivity

Popular Abstract in Swedish Avhandlingen består av fyra kapitel som behandlar olika aspekter av internationell handel och dess effekter på konkurrens och produktivitet. Särskilt behandlas effekterna av EU:s expansion och fördjupade integration. Första kapitlet använder den så kallade gravitationsmodellen för att analysera hur integrationsprocessen av de Central- och Östeuropeiska länderna i EU haThis thesis consists of four papers on trade, competition and productivity with particular emphasis on the effects of various aspects of the deepening and widening of the European Union. The first paper Trade Creation, Diversion and Displacement of the EU Enlargement Process provides an assessment of the effects of the EU enlargement process on trade. A new method of estimating the gravity model

Protection against cold in prehospital care — thermal insulation properties of blankets and rescue bags in different wind conditions

Introduction: In a cold,wet, or windy environment, cold exposure can be considerable for an injured or ill person. The subsequent autonomous stress response initially will increase circulatory and respiratory demands, and as body core temperature declines, the patient’s condition might deteriorate. Therefore, the application of adequate insulation to reduce cold exposure and prevent body core cool

Liposuction and Controlled Compression Therapy in the Treatment of Arm Lymphedema following Breast Cancer

Popular Abstract in Swedish Liposuction och kontrollerad kompressionsbehandling av armlymfödem efter bröstcancerbehandling Behandlingen av bröstcancer är kirurgisk. Förutom att bröstet avlägsnas innefattar behandlingen ofta borttagning av lymfkörtlar i armhålan samt strålbehandling. Detta leder till att flödet av lymfa från armen kraftigt försämras med svullnad som följd (lymfödem). Detta inträffLiposuction and controlled compression therapy in the treatment of arm lymphedema following breast cancer About one-third of all women treated for breast cancer develop arm lymphedema. The cancer itself is a worry, but the swollen and heavy arm is an additional handicap for the patients, both physical and psychosocial. Previous surgical and conservative treatments have not always given satisfacto

Force Feedback for Assembly of Aircraft Structures

Variability in composite manufacture and the limitations in positional accuracy of common industrial robots have hampered automation of assembly tasks within aircraft manufacturing. One way to handle geometry variations and robot compliancy is to use force control. Force control technology utilizes a sensor mounted on the robot to feedback force data to the controller system so instead of being po