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ObjectiveIncreased nuchal translucency originates from disturbed lymphatic development. Abnormal neural crest cell (NCC) migration may be involved in lymphatic development. Because both neuronal and lymphatic development share retinoic acid (RA) as a common factor, this study investigated the involvement of NCCs and RA in specific steps in lymphatic endothelial cell (LEC) differentiation and nucha
Cyclometallated aryl-pyridine gold(iii) complexes are shown to be efficient catalysts for the multicomponent reaction between N-benzyl imines, alkynes, and acyl chlorides to form trisubstituted oxazoles. The reaction typically proceeds in good yields (up to over 80%) and short reaction times (∼15 minutes). The high stability of the investigated cyclometallated catalysts enables a retained efficien
Background:Angiosarcomas may develop as primary tumours of unknown cause or as secondary tumours, most commonly following radiotherapy to the involved field. The different causative agents may be linked to alternate tumorigenesis, which led us to investigate the genetic profiles of morphologically indistinguishable primary and secondary angiosarcomas.Methods:Whole-genome (18k) c-DNA-mediated annea
The development of physiologic monitors has contributed to the decline in morbidity and mortality in patients undergoing anaesthesia. Diverse factors (physiologic, technical, historical and medico-legal) create challenges for monitor alarm designers. Indeed, a growing body of literature suggests that alarms function sub-optimally in supporting the human operator. Despite existing technology that c
Introduction: We studied the release of propranolol hydrochloride (PHCl), a water-soluble amphiphilic drug, from monoolein (MO)/water and phytantriol/water systems. Methods: We related the dissolution profiles with phase behavior and viscosity of the different liquid crystalline phases. Diolein has been added aiming to stabilize the cubic phases and thus preventing formation of less viscous (lamel
Background/Aims: Factors including rate of disease progression, different aspects of cholinesterase inhibitor (ChEI) treatment, and use of community-based services might affect the longitudinal outcome of Alzheimer’s disease (AD). Whether these factors alter life expectancy in AD is unclear. We therefore examined the association between long-term ChEI therapy and survival. Methods: The present stu
Pili have only been discovered in the major Gram-positive pathogens in the past decade and they have been found to play an important role in colonisation and virulence. Pili have been shown to have many important functions including attachment to host tissues, mediating bacterial aggregation, biofilm formation and binding to proteins in the extracellular matrix. In this study, sortase-dependent pi
A palynological study of the upper Silurian Oved-Ramsasa Group in Skane, Sweden yields a well preserved spore assemblage with low relative abundances of marine microfossils. In total, 26 spore taxa represented by 15 genera were identified. The spore assemblage is dominated by long-ranging cryptospore taxa, and the trilete spore Ambitisporites avitus-dilutus. However, key-species identified include
Elevated concentrations of arsenic in drinking water are common worldwide, however, little is known about the presence of other potentially toxic elements. We analyzed 31 different elements in drinking water collected in San Antonio de los Cobres and five surrounding Andean villages in Argentina, and in urine of the inhabitants, using ICP-MS. Besides confirmation of elevated arsenic concentrations
Abstract in UndeterminedCrisis communication is a growing field of research and practice. A weakness in the traditional research field is the lack of theoretical development and the isolated sender and mass communication focus. In the present paper, we challenge traditional research by focusing on the contemporary cultural and ethnic diversity in society from an audience-oriented media perspective
The aim of this thesis was to develop a way to evaluate the mobility of the wrist or hand after an injury. To do this a prototype of a compression glove with added conductive silicone was made. A tensile test was done first to test linearity between resistance and elongation. Thereafter this was implemented on the prototype. The silicone, Elastosil LR3162 showed good proprieties for the purpose w
Pornografi har de senaste decennierna blivit alltmer lättillgängligt och närmast oändligt i utbud. Det kan införskaffas anonymt och gratis. Användandet är utbrett och börjar ofta i unga åldrar. Trots att många rapporterar att deras användande av pornografi och annat sexuellt explicit material (SEM) är problematiskt saknas en vedertagen konceptualisering. Denna studies syfte var att beskriva den raPornography has become increasingly accessible and almost infinite in supply. It can be used anonymously and for free. The use is widespread and often starts at a young age. Despite large numbers of people reporting problematic use of pornography and other sexually explicit material (SEM), the problem lacks an officially recognized conceptualization. The purpose of the present study was to investi
The soot emissions from diesel engines are much higher in transient operation than during steady state operation. In this thesis, a method for estimating the soot mass flow emission in transient drive cycles is presented. The proposed method uses stationary emission maps in combination with step responses. Bandpass filters are used to filter the engine torque/power to provide transient detection a
Building information modelling, BIM, is a well-known and established conception within the construction business. In the building industry BIM technology is used as a tool and a work method by different occupational groups within planning, production and facility management. Due to the usage of BIM differs between the fields, so does the software’s as well. The software’s are using different types
1 LUND UNIVERSITY | 2016 Climate Research at Lund University - and in Sweden LUND UNIVERSITY | 2016 2 LUND UNIVERSITY | 2016 Climate change is a real, challenging and urgent matter for the world, all countries, the public and the private sector as well as civil society. Climate change is intimately connected to other global challenges that need to be tackled in order to achieve sustainable develop
Ungdomskriminaliteten har särskilt under de senare åren varit ett ämne som ständigt uppkommit i den kriminalpolitiska debatten. Regeringen gav under 2021 en särskild utredare i uppdrag att genomföra en översyn av regleringen om frihetsberövande påföljder för barn och att utifrån denna presentera förslag på lämpliga förändringar. Detta resulterade i SOU 2023:44 som presenterades i augusti 2023. I dJuvenile delinquency has in recent years been a topic that has constantly arisen in the justice policy debate and in 2021 the government appointed an inquiry chair to carry out a review of the regulations on custodial penalties for children, and on the basis of this investigation present proposals for suitable revisions. This resulted in SOU 2023:44 which was presented in August of 2023. In this,
