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For cells to function correctly within an organism, they need different systems to communicate with each other. One crucial part of cell signaling is the proteoglycans (PGs) and glycosaminoglycans (GAGs), which are macromolecules that bind different signaling molecules and proteins necessary for processes such as growth and proliferation. Therefore, PGs and GAGs are involved in pathological proces

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Nine adults were interviewed in order to illuminate the meanings of being dependent on a ventilator and living at home. The data were analysed using a phenomenological-hermeneutic method inspired by the philosophy of Ricoeur. Five main themes emerged through the analysis: experiencing home as a safe and comfortable space from which to reach out, experiencing the body as being frail, brave and resi

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The aim of the present study is to develop a mathematical model for evaluating therapeutic response of combined treatment modalities. The study was performed in rats of the Fischer-344 strain with rat glioma N32 or N29 tumors implanted subcutaneously on the thigh of the hind leg. Pulsed electric fields, PEF, with 16 exponentially decaying pulses with a maximum electric field strength of 140 V/mm a

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We have developed an electrochemical cell for in situ 2-Dimensional Surface Optical Reflectance (2D-SOR) studies during anodization and cyclic voltammetry. The 2D-SOR signal was recorded from electrodes made of polycrystalline Al, Au(111), and Pt(100) single crystals. The changes can be followed at a video rate acquisition frequency of 200 Hz and demonstrate a strong contrast between oxidizing and

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PURPOSE: The DIANA study aimed to evaluate how often antimicrobial de-escalation (ADE) of empirical treatment is performed in the intensive care unit (ICU) and to estimate the effect of ADE on clinical cure on day 7 following treatment initiation.METHODS: Adult ICU patients receiving empirical antimicrobial therapy for bacterial infection were studied in a prospective observational study from Octo

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OBJECTIVE: /st> To investigate the effect of tumour necrosis factor (TNF) antagonist treatment of patients with rheumatoid arthritis (RA) on sick leave (SL) and disability pension (DP) in a population-based setting in southern Sweden. METHODS: /st> All patients with RA in the South Swedish Arthritis Treatment Group register living in the county of Skåne (population 1.2 million), who started their

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Objective. To evaluate the effects on neonatal morbidity of a regional change in induction policy for post-term pregnancy from 43(+0) to 42(+0) gestational weeks (GWs). Design and setting. Nationwide retrospective register study between 2000 and 2007. Population. All singleton pregnancies with a gestational age of >41(+2) GW (n= 119,198). Methods. All Swedish counties were divided into three group

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Carotid endarterectomy (CEA) is a standardized surgical procedure and is the third most common vascular surgical procedure in Sweden. To improve the quality of pre- and postoperative care for patients undergoing elective CEA, a standardized care plan (SCP) was developed and implemented during Spring of 2007 at a vascular clinic in Sweden. In order to spread light on obstacles and possibilities in

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Abstract in UndeterminedCrisis communication is a growing field of research and practice. A weakness in the traditional research field is the lack of theoretical development and the isolated sender and mass communication focus. In the present paper, we challenge traditional research by focusing on the contemporary cultural and ethnic diversity in society from an audience-oriented media perspective

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It is a commonplace to suggest that liberal theory should construct principles which are race-neutral, that policies should be ‘color-blind1. This study criticizes the description of race neutrality in recent theories of political liberalism. The author begins by addressing recent writings on political liberalism by John Rawls, and explores the assumptions about racial practices which support Rawl

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The aerobic biodegradation of toxic organic volatile contaminants is always limited by the low aqueous solubility of O2. Therefore, intensive bubbling or surface aeration is required to supply the bacterial community with sufficient O2 to carry out pollutant mineralization. This can cause the hazardous volatilization of toxic volatile contaminants. Photosynthetic oxygenation overcomes these limita

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The recent growth in research on "good governance" and the quality of government institutions has been propelled by empirical findings that show that such institutions may hold the key to understanding economic growth and social welfare in developing and transition countries. We argue, however, that a key issue has not been addressed, namely, what quality of government (QoG) actually means at the

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All species of Hieracium sectt. Hieracium, Vulgata (incl. Bifida) and Oreadea originally described from the Nordic countries, but reported in recent accounts as occuring in the British Isles, have been scrutinised based on specimens and published descriptions. Out of 29 species stated as occurring in Britain and native to Fennoscandia, only four are confirmed (H. caesiomurorum, H. oistophyllum, H.

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Ethical questions related to globalisation, human rights, unfair labour practices and transboundary exchanges of capital and workforce create ever more complex challenges for the tourism sustainability agenda. In recent years, the tourism industry has been increasingly challenged by media and governments to provide fast, socially responsible responses to emerging problems resulting from the dissol

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A novel aluminium rich alloy for hydrogen storage has been discovered, ScAl0.8Mg0.2, which has very promising properties regarding hydrogen storage capacity, kinetics and stability towards air oxidation in comparison to hydrogen absorption in state-of-the-art intermetallic compounds. The absorption of hydrogen was found to be very fast, even without adding any catalyst, and reversible. The discove

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This thesis describes functional studies of the human protein alpha-1-microglobulin (A1M), with the aim of exploring its usefulness as a therapeutic agent in diseases where oxidative stress is a prominent feature. A1M is a 26 kDa plasma and tissue protein with reductase activity and radical- and heme-binding antioxidative functions. The research focus in this thesis has been to study the in vivo p

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The common genetic variants associated with complex traits typically lie in noncoding DNA and may alter gene regulation in a cell type-specific manner. Consequently, the choice of tissue or cell model in the dissection of disease associations is important. We carried out an expression quantitative trait loci (eQTL) study of primary human osteoblasts (HOb) derived from 95 unrelated donors of Swedis

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This paper presents a search for the t-channel exchange of an R-parity violating scalar top quark ((t) over tilde) in the e(+/-)mu(-/+) continuum using 2.1 fb(-1) of data collected by the ATLAS detector in root s = 7 TeV pp collisions at the Large Hadron Collider. Data are found to be consistent with the expectation from the Standard Model backgrounds. Limits on R-parity-violating couplings at 95