Filtyp
AIMS: Extracellular ATP modulates pulsatile release of insulin, glucagon and somatostatin by activating P2Y(1) receptors. The present study examines if adenosine via A(1) receptors (A(1)R) interferes with pulsatile islet hormone release. MAIN METHODS: Pancreas was perfused in mice expressing or lacking the A(1) receptor and the hormones measured with radioimmunoassay. Cytoplasmic Ca(2+) was record
BACKGROUND: To investigate the correlation between various orthopedic conditions and overweight/obesity at the Department of Orthopedics, Malmö University Hospital Sweden. Obesity is associated with numerous major medical conditions. Although the relationship between gonarthrosis and osteoarthritis and body mass index (BMI) is well recognized, other orthopedic conditions have been less well studie
Background: In the 1950s, Sweden initiated prophylaxis as a lifelong treatment for haemophilia. It was the first country to do so. Objective: To describe and evaluate dosing and outcome of prophylactic treatment in a large cohort of adult people with severe haemophilia who have been using prophylaxis most of their lives. Methods: Eighty-one patients born between 1932 and1992 were divided into two
BACKGROUND: To assess and compare the feasibility and stressful memories of light vs. heavy sedation during post-operative mechanical ventilation. METHODS: Randomized clinical trial in one general intensive care unit (ICU) in a Swedish university hospital. Thirty-six adults were randomly assigned to receive either light [Motor Activity Assessment Scale (MAAS) 3-4] or heavy (MAAS 1-2) sedation with
BACKGROUND:: Epidemiological reports on risk and prognostic factors in patients with mesenteric venous thrombosis (MVT) are scarce. METHODS:: Patients with MVT were identified through the inpatient and autopsy registry between 2000 and 2006 at Malmö University Hospital. RESULTS:: Fifty-one patients had MVT, diagnosed at autopsy in six. The highest incidence (11.3 per 100 000 person-years) was in t
BACKGROUND: Alpha-1-antitrypsin (AAT) deficiency increases the risk of emphysema, especially in smokers. In 1972-1974, all 200,000 Swedish new-born infants were screened for AAT deficiency and individuals with severe (PiZZ) and moderate (PiSZ) deficiency have been followed-up regularly. The aim of the present study was to examine their lung function at the age of 30years, comparing them to a group
How are public spaces regulated in tourist cities? In this doctoral dissertation I seek to answer this question by exploring the intersections between urban tourism and public space regulation. I argue that public space regulation substantially differs from the tourist to the non-tourist zone. This thesis contradicts the common belief that public space regulation may vary from city to city, but re
The strong focus on decreasing carbon dioxide emissions due to limited natural resources of fossil fuel as well as alarming climate changes drives the research and development of our prime mover, the combustion engine, faster then ever. The minimum requirement is a power source with increased efficiency while emitting ultra low levels of hazardous local and regional emissions. The concept of Homog
PURPOSE: The purpose of this study is to investigate the results of first-time surgery for sporadic primary hyperparathyroidism (pHPT) in patients with preoperatively negative sestamibi scintigraphy and ultrasound. METHODS: Data were gathered prospectively in a multicenter database for quality control in parathyroid surgery. Between 2004 and 2008, 3,158 patients underwent first-time surgery for sp
Background: Escalating resistance among Gram-negative pathogens limits β-lactam options. Cefepime/enmetazobactam combines a fourth-generation cephalosporin with a class A β-lactamase inhibitor. We evaluated its activity against multidrug, extensive and pandrug-resistant war-wound isolates from Ukraine.Materials and methods: We tested 215 clinical samples (2022-2023) isolated from wounded patients
The intense photon fluxes from relativistic nuclei provide an opportunity to study photonuclear interactions in ultraperipheral collisions. In particular, it allows for the investigations of excited, light-flavour vector mesons. The measurement of coherently photoproduced π+π−π+π− final states in ultraperipheral Pb–Pb collisions at sNN=5.02 TeV is presented for the first time. The cross section, d
Context. While the influence of the LMC on Milky Way (MW) stellar streams has been extensively studied, streams associated with the Clouds have received far less attention. Beyond the Magellanic Stream, only four stream candidates (S1–S4) have been reported. Aims. We focus on the S3 stream, a long (~30°) and narrow (~1.2°) structure at 60–80 kpc that is nearly aligned with the LMC. Our goals are:
This special issue addresses questions of how the practices of (welfare) state practitioners and policy makers (trans)form the lives of families. The aim is to illuminate how social policies and educational institutions influence parents’ hope for the wellbeing and future success of their children through new forms of audit culture and policies of early interventions. We i
BACKGROUND: Growing concerns over the environmental and human health impacts of conventional insecticides have intensified interest in botanical alternatives, including essential oils. However, their compositional complexity poses challenges for quality control and consistent efficacy. This study evaluated and compared the predictability of nonparametric and parametric models for predicting the mi
BACKGROUND: Vacuum-assisted abdominal closure (VAC) is being increasingly used as an adjunctive procedure in the surgical treatment of secondary peritonitis. This study compared postoperative mortality and complication rates between VAC and primary abdominal closure (PAC).METHOD: This retrospective chart review included all patients diagnosed with secondary peritonitis who underwent laparotomy bet
This non-interventional post-authorisation safety study (PASS) assessed the long-term safety of everolimus in patients with tuberous sclerosis complex (TSC) who participated in the TuberOus SClerosis registry to increase disease Awareness (TOSCA) clinical study and received everolimus for the licensed indications in the European Union. The rate of adverse events (AEs), AEs that led to dose adjustm
Edit Farkas and László Lőkös are internationally well known and respected Hungarian lichenologists. They did their best to maintain and to develop several aspects of the Hungarian lichenology, including biodiversity research on lichen-forming and lichenicolous fungi, taxonomic revisions based on morphological, chemical and molecular methods, ecological, ecophysiological and conservation biological
