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In the area of environment adaptations for people with physical disabilities, it is of vital importance that the design is optimized considering the human-environment interactions. All involved persons in such a planning process must be given sufficient support in understanding the information, so that everyone can participate actively. There is an apparent risk that discussions will be kept betwe
A study to determine and compare the sensitivities and specificities of the comparative cervical tuberculin (CCT) and gamma-interferon (IFN-gamma) tests for the diagnosis of bovine tuberculosis was conducted on 30 zebu oxen. The results of the tests were compared with the presence of acid-fast bacilli found by bacteriological culturing and histopathological examinations. The sensitivity and specif
Purpose: To suggest a more precise tool when assessing the risk of contrast-medium-induced nephropathy (CIN), i.e. the ratio between contrast medium (CM) dose expressed in grams of iodine (g-I) and estimated glomerular filtration rate in ml/min (eGFR; based on equations using serum-creatinine (s-Cr), weight, height, age, and/or sex), here named I-dose/GFR ratio. Material and Methods: A Medline sea
Background: CD4-independence has been taken as a sign of a more open envelope structure that is more accessible to neutralizing antibodies and may confer altered cell tropism. In the present study, we analyzed SIVsm isolates for CD4-independent use of CCR5, mode of CCR5-use and macrophage tropism. The isolates have been collected sequentially from 13 experimentally infected cynomolgus macaques and
Car developers use digital human modeling tools to analyze and visualize car interiors in relation to human characteristics before the vehicles are actually constructed. Developers, reviewers and users of human simulation tools often claim that such tools can reduce development time and costs. In car industry companies today, human simulation tools are used by a single or a few experts in an infor
Background: More knowledge is needed on potential associations between individual-, family-, and neighborhood-level factors and psychiatric disorders in children and adolescents. Aims: To examine associations between, individual-, family-, and neighborhood-level factors and incident internalizing (anxiety and mood) disorders and externalizing (ADHD and conduct) disorders in children and adolesc
Nanotechnology gives us materials with enhanced or completely new properties. At the same time, inhalation of manufactured nano-objects has been related to an array of adverse biological effects. We characterized particle emissions, which occurred during maintenance of common metal nanoparticle generators and contrasted the properties of the emitted particles with those originally produced by the
Background Several candidate genes have been found to be associated with the inflammatory response of IgE-mediated allergy, so also the immunoglobulin constant heavy G chain (IGHG) genes. The IGHG genes are situated close to the IGHE gene on chromosome 14q32, 5'μ, δ, γ3, γ1, α1, γ2, γ4, e, α2, 3'. They are inherited in a Mendelian fashion and expressed randomly in allelic exclusion. The alternativ
Introduction Aggrecanase cleavage at the (392)Glu-(393)Ala bond in the interglobular domain (IGD) of aggrecan, releasing N-terminal (393)ARGS fragments, is an early key event in arthritis and joint injuries. Here, we use a quantitative immunoassay of aggrecan ARGS neoepitope fragments in human synovial fluid to determine if this cleavage-site specific method better identifies joint pathology than
Popular Abstract in Swedish Människor har i alla tider försökt reparera och ersätta skadade vävnader i kroppen. Förr användes naturliga material som t. ex. bomull, silke, tagel och läder. Under 1900-talet har flera syntetiska (konstgjorda) material utvecklats, framförallt olika typer av polymerer (plaster), för användning som ersättning av skadade kroppsvävnader. Beroende på vilken typ av vävnad s
Popular Abstract in Swedish Peptidaser, proteolytiska enzymer eller proteinhydrolaser är olika benämningar på samma sorts enzymer. Deras funktion är att bryta ner proteiner i alla celler, vävnader eller vätskor i antingen vår egen kropp eller i någon annan levande organism. Varför behövs dessa enzymer? Deras funktion påminner om den av en återvinningscentral, där peptidaserna avvecklar felfungeraProteolytic enzymes are enzymes that hydrolyze peptide bonds in peptides and proteins. This ability to carry out protein degradation is essential for many cellular and extracellular processes that occur in all living organisms. Cysteine peptidases constitute a class of proteolytic enzymes. Among these, papain-like (C1) peptidases are the mostly studied ones. Inhibitors regulate proteolytic activit
Wireline communication is the Internet access technology with the largest number of subscribers worldwide. On physical-layer level, the traditional way to transmit signals at one end of a wire pair and to extract receive signals at the other end is to apply differential-mode signalling: transmit and receive signals correspond to voltage differences between the two wires. Differential-mode signalli
Objectives: To examine the risk of putative pneumococcal infections in adult arthritis patients on different anti-rheumatic drugs immunized with heptavalent pneumococcal conjugate vaccine (Prevenar 7; PCV7) and non-vaccinated individually matched arthritis patients. Method: All individuals in a cohort of 505 patients with rheumatoid arthritis (RA) or spondylarthropathy (SpA) receiving different an
Background. A 43-year-old woman was referred by her occupational health service with suspected occupational contact dermatitis. In connection with the investigation, a workplace visit was undertaken at her company, which used an adhesive based on pre-polymeric diphenylmethane diisocyanate in one of its units. During the visit, we became aware of six other employees with skin problems who were then
In Sweden, only a few empirical studies of couple therapy have been performed. This is the hitherto most comprehensive assessment of clinical treatment. Effectiveness of treatment is reported and compared with non-clinical ratings. Initially the couples displayed marital distress, many psychiatric symptoms, dyadic interactions characterized by high criticism and a low sense of coherence. In Sweden
Protein D is a surface-exposed lipoprotein of the gram-negative bacterium Haemophilus influenzae with affinity for human immunoglobulin D myeloma protein. The gene encoding protein D (hpd) in a serotype b strain of H. influenzae was cloned. Escherichia coli carrying the hpd gene bound human myeloma immunoglobulin D. Nucleotide sequence analysis identified an 1,092-bp open reading frame that was mo
In birds and mammals with sexual size dimorphism (SSD), the larger sex is typically more sensitive to adverse environmental conditions, such as food shortage, during ontogeny. However, some recent studies of altricial birds have found that the larger sex is less sensitive, apparently because large size renders an advantage in sibling competition. Still, this effect is not an inevitable outcome of
