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Subclinical atherosclerosis and its progression are modulated by PLIN2 through a feed-forward loop between LXR and autophagy

Background: Hyperlipidaemia is a major risk factor for cardiovascular disease, and atherosclerosis is the underlying cause of both myocardial infarction and stroke. We have previously shown that the Pro251 variant of perilipin-2 reduces plasma triglycerides and may therefore be beneficial to reduce atherosclerosis development. Objective: We sought to delineate putative beneficial effects of the Pr

Oral Contraceptive Use and Breast Cancer Risk : Retrospective and Prospective Analyses From a BRCA1 and BRCA2 Mutation Carrier Cohort Study

Background: For BRCA1 and BRCA2 mutation carriers, the association between oral contraceptive preparation (OCP) use and breast cancer (BC) risk is still unclear.Methods: Breast camcer risk associations were estimated from OCP data on 6030 BRCA1 and 3809 BRCA2 mutation carriers using age-dependent Cox regression, stratified by study and birth cohort. Prospective, left-truncated retrospective and fu

H e (a) r: Of an ecological enactive perspective

An audio paper on H e (a) r; a soundscape connected to ecology, acoustics and embodiment, drawing on encounters and what happens in the connection. A fluctuation between hear-here-hér*-her. Originating in a work for the ensemble Nordic Affect’s concert at Nordic Music Days 2016, the piece has now been developed into both a quadrophonic and stereo version of H e (a) r (2017/18). The work has been r

Expression of thermal tolerance genes in two Drosophila species with different acclimation capacities

Heat tolerance increases at higher acclimation temperatures in D. melanogaster, but not in D. subobscura. The two species represent separate lineages of the subgenus Sophophora of Drosophila with contrasting tropical African and temperate Palearctic evolutionary histories. D. melanogaster has five copies of the inducible hsp70 gene distributed in two clusters, named A (with two copies) and B (thre

Bayesian argumentation : The practical side of probability

Relevant to, and drawing from, a range of disciplines, the chapters in this collection show the diversity, and applicability, of research in Bayesian argumentation. Together, they form a challenge to philosophers versed in both the use and criticism of Bayesian models who have largely overlooked their potential in argumentation. Selected from contributions to a multidisciplinary workshop on the to

Comparison between interstitial laser thermotherapy and excision of an adenocarcinoma transplanted into rat liver

The aim of this study was to compare interstitial laser thermotherapy with excision of a liver tumour. A dimethylhydrazine-induced adenocarcinoma was transplanted (implanted if not stated otherwise) into the left lateral lobe of the rat liver, and treatment was performed 8 days later. In the main experiment, rats were treated with resection of the tumour-bearing robe or underwent interstitial lase

Interstitial laser thermotherapy of a rat liver adenocarcinoma

The aim of this study was to compare interstitial laser thermotherapy with excision of a liver tumour. A dimethylhydrazine-induced adenocarcinoma was implanted into the left lateral lobe of the rat liver, and treatment was performed 8 days later. Rats were treated with resection of the tumour-bearing lobe or underwent interstitial laser thermotherapy, which was performed at a steady-state temperat

The link between plasticity parameters and process parameters in orthogonal cutting

In the present study the plasticity parameters in the Johnson Cook plasticity model are determined on the basis of process parameters in orthogonal cutting by use of inverse analysis. Previously established links between material parameters and process parameters in the cutting process such as chip thickness ratio, cutting forces, temperatures, deformation zones, is used serve as a starting point

Scaling of migration and the annual cycle of birds

In a seasonally fluctuating environment migratory birds face decisions relating to how to schedule their main life-history activities, i.e. breeding, moult and migration. The time required to complete any one of these depends on overall size. In this paper I derive scaling functions about how time required for breeding, moult and migration depends on body mass. The sum of these increases with incr

Experimental investigations of potassium chemistry in premixed flames

Quantitative potassium species concentrations have been measured in alkali-seeded premixed methane-air flames of different stoichiometry. Potassium chloride (KCl) and hydroxide (KOH) were measured by broadband UV absorption spectroscopy and laser-induced photofragmentation fluorescence, while atomic potassium was measured using tuneable diode-laser spectroscopy. In addition, laser Rayleigh scatter

Lp-PLA2 activity and mass for prediction of incident abdominal aortic aneurysms : A prospective longitudinal cohort study

Background and aims The pathogenesis of abdominal aortic aneurysm (AAA) shares several common pathways with atherosclerosis. Prospective clinical plasma biomarker studies in AAA have been hampered by the need for very large cohorts and long follow-up time. Methods We analyzed a prospective longitudinal cohort of middle-aged individuals from the cardiovascular cohort of the Malmö Diet and Cancer st

Lunds-universitets-magasin-6-2010

LUM Lunds universitets magasin | Nr 6 | 2010 BLöt fest Bättre arbetsvillkor enligt ny plan Godhet – arv eller miljö? 2 LUM nr 6 | 2010 KarnevaaaL! LUM nr 6 | 2010 3 Trots namnet blev Rätt och fel-kar- nevelen anno 2010 mest rätt. Fem- tusen engagerade studenter, ca 100.000 besökare om dagen, vack- ert väder, underhållning av hög klass både av studenter och till- resta artister – allt borgade för e

https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-6-2010.pdf - 2026-06-08

Lu service vp 19 webb 1

Verksamhetsplan 2019 LU SERVICE | LUNDS UNIVERSITET Vision, uppdrag, mål, projekt och aktiviteter .................... 4 LU Service–en del av Gemensamma förvaltningen ........... 6 Avdelningar .................................................................... 8 Medarbetare .................................................................. 10 Systematiskt arbetsmiljö- och riskarbete .............

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/lu_service_vp_19_webb_1.pdf - 2026-06-08

Long-term retention of neurotoxic beta-carbolines in brain neuromelanin

beta-Carbolines show structural resemblance to the neurotoxic N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and are metabolized to mitochondrial toxicants. Humans are continuously exposed to low levels of beta-carbolines through cooked food, coffee, alcoholic beverages and tobacco smoke. beta-Carbolines have previously been detected in higher levels in the pigmented substantia nigra than in the cor

AI Policy – Department of Economic History

The Department of Economic History recognises the rapid increase in the use of AI-based tools in fields related to the education we provide and in society at large. We recognise that these tools are likely to remain accessible to students. To ascertain that the tools are used responsibly, ethically, and in ways that promote and accelerate student learning while safeguarding examination by working

https://www.lusem.lu.se/organisation/department-economic-history/study-economic-history/current-student-economic-history/ai-policy-department-economic-history - 2026-06-08

Hur majoriteter kan ta kontroll över tillgångars avkastningsförmåga - En jämförelse mellan aktie- och inkråmsöverlåtelser ur ett aktieägarminoritetsperspektiv

En aktieägare i ett tillgångsägande aktiebolag, som vill få egenhändig kontroll över en tillgångs avkastningsförmåga, har idag två möjliga vägar att välja mellan för att uppnå sitt mål. Denne kan förvärva aktier i bolaget eller förvärva, direkt eller indirekt, själva tillgången. Beroende på vilken väg som väljs kommer aktieägaren stöta på olika typer av hinder. Denna uppsats syftar till att redogöA shareholder in an asset holding company, who wishes to gain direct control over the asset's capacity to produce profit, currently has two possible paths to choose from in order to achieve his or her goal. He or she can either acquire shares in the company or directly or indirectly acquire the asset itself. Depending on the chosen path, the shareholder will encounter different types of obstac

Automation of High-accuracy Marking Tasks at MAX IV using the Quadrupedal Robot Spot

When installing new research equipment at the synchrotron research laboratory MAX IV, a final positional accuracy of tens of microns is usually needed. To obtain that accuracy, initial reference points must be placed within 2 mm from the nominal target points in CAD, in a process referred to as bluelining. It is currently a manual process where points from a virtual environment are transferred to