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Sesquiterpene lactone mix detects contact allergy to these compounds present in the plant family Asteraceae. This marker is present in many baseline series. An additional marker is Compositae mix, which is not present in many baseline series. To investigate whether this allergen should be inserted into the Swedish baseline series, sex dermatology centres representing the Swedish Contact Dermatitis
1 INTRODUCTION In a global and highly competitive economy, companies have now adopted an increasingly integrated ap-proach to product development. However, packaging logistics has been left out from this integration trend. The reasons are multiple: first packaging is not considered to be an integral part of the product, so it is not part of the product “culture” of the company. In most companies,
Popular Abstract in Swedish Populärvetenskaplig sammanfattning Felaktig DNA-reparation av typen mismatch repair (MMR) uppkommer i 15-17% av cancer i tjock- och ändtarm (kolorektalcancer). MMR defekter är av betydelse i tre situationer: • MMR defekta tumörer har en bättre prognos än övrig tjock- och ändtarmscancer, vilket kan användas för att avgöra huruvida en patient skall erbjudas sk. adjuvant Mismatch repair (MMR) deficiency is carcinogenic and can either have somatic/sporadic causes (i.e. epigenetic silencing or somatic inactivation) or hereditary causes (Lynch syndrome due to a germline mutation in one of the MMR genes ¬- MLH1, MSH2, MSH6, PMS2). The identification of MMR defective colon cancer is clinically relevant for diagnostic, prognostic and potentially also for treatment-predi
To further understanding of the genetic basis of type 2 diabetes (T2D) susceptibility, we aggregated published meta-analyses of genome-wide association studies (GWAS), including 26,488 cases and 83,964 controls of European, east Asian, south Asian and Mexican and Mexican American ancestry. We observed a significant excess in the directional consistency of T2D risk alleles across ancestry groups, e
Popular Abstract in Swedish I Sverige finns cirka 350 000 personer med diabetes. Motsvarande siffra i hela världen är cirka 350 miljoner människor och forskning talar för att antalet personer med diabetes kommer att öka dramatiskt under de närmsta decennierna. Den största ökningen sker i utvecklingsländer i urbana områden, till stor del beroende på livsstilsförändringar och förändringar i diet. UtSpecific aims: To examine whether the sociodemographic characteristics of patients with type 2 diabetes affect the odds of reaching the recommended treatment goals for HbA1c and blood lipids (study 1). To investigate whether the odds of coronary heart disease are higher in patients with diabetes living in deprived neighborhoods than in those living in wealthy neighborhoods (Study 2). To examine th
Background: The global gene regulator Special AT-rich sequence-binding protein1 (SATB1) has been reported to reprogramme tumour cells into a more malignant phenotype and associate with poor clinical outcome in several cancer forms. In this study, we investigated the molecular correlates and prognostic impact of SATB1 expression in human epithelial ovarian cancer (EOC). Findings: Immunohistochemica
Apolipoprotein M (apoM) is composed of 188 amino acids and has an apparent molecular weight of 25 kDa. ApoM belongs to the lipocalin protein superfamily, and is found in all major lipoprotein classes, although the majority of apoM is found in high density lipoprotein, HDL. In apoM, the signal peptide is retained in the mature protein. ApoM with a cleavable signal peptide was constructed. In contra
Context. The Gaia-ESO Survey (GES) is a large public spectroscopic survey at the European Southern Observatory Very Large Telescope. Aims. A key aim is to provide precise radial velocities (RVs) and projected equatorial velocities (v sin i) for representative samples of Galactic stars, which will complement information obtained by the Gaia astrometry satellite. Methods. We present an analysis to e
Contracts in the EU operate in a complex legal environment. Depending on the situation, they are subject to a patchwork of national, European, and international rules. As a result, economic operators exercising the ‘four freedoms’ find themselves in a great ocean of private international law, containing smaller islands of EU law and national rules. This paper explores some of the fundamental issu
En ny anställningsform som växt fram i digitaliseringens fotspår är arbete som utförs via digitala plattformar. Plattformsarbete är en del av en större pågående strukturell förändring, nämligen flexibiliseringen av arbetsmarknaden. Denna strukturella förändring gör att den nuvarande gränsen mellan arbetstagare och uppdragstagare suddas ut. Begreppet arbetstagare anger gränserna för arbetslagstiftnWork supplied through digital platforms is a new form of employment that has emerged in the course of digitalization. Platform work is part of a bigger ongoing structural shift, namely the flexibilisation of working life. This structural shift blurs out the distinction between an employee and a self-employed worker. The personal scope of Swedish labor law is defined by use of the notion of employe
Rekvisitet ”verksam i betydande omfattning” återfinns i bland annat 57 kap. 4 § inkomstskattelagen och är vagt formulerat. Den här uppsatsen har som syfte att utreda och analysera rekvisitets innebörd. Syftet uppnås genom att undersöka vilka faktorer som har betydelse för när verksamhet i betydande omfattning anses föreligga samt hur dessa faktorer förhåller sig till varandra. Studien har genomföThe legal criterion ”verksam i betydande omfattning” can for instance be found in 57 Ch. 4 § inkomstskattelagen and is vaguely formulated. The purpose of this paper is to examine and analyse the meaning of the criterion. The purpose will be achieved by investigating what factors are significant for when “verksamhet i betydande omfattning” is considered to be met, as well as investigating how these
The main purpose of this study was to identify aspects of municipal risk and vulnerability analyses that are of importance to the perceived usability at a regional level. The first part of the study aimed to encode the content of municipal risk and vulnerability analyses from the counties of Scania and Stockholm. The results were then correlated against rankings of the analyses established by the
As our lives ever increasingly move online, the influence of social media is constantly growing. It has however proven difficult for legislators to keep up with rapid development of online spaces. Therefore, legislative control has largely been left to the social media platforms. To see if this is a good solution, this paper aims to analyze Twitters terms of use, rules, guidelines, and policies, i
The rapid development of China's outbound tourism in European countries is receiving more and more attention from the European tourism industry. The improvements of the national economy, the characteristics of Chinese culture and the strengthening of the economic and cultural bonds between China and European Union countries have all played roles in its growth. This master thesis summarizes Chi
This paper selected two cities in Zhejiang Province, Wenzhou and Yiwu to take a look at the relations between the local government and their private sector since the adoption of the reform and opening policy in the late 1970s, from the angle of the functional transition of the local government's contribution to the development of the private sector. The purpose of this paper was to, through th
