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Purpose. In this work we explore a method named clinical grading analysis (CGA) which is based on clinical assessments performed by radiation oncologists (ROs). The purpose is to investigate how useful the method is for treatment plan comparisons, and how the CGA results correlate with dosimetric evaluation parameters, traditionally used for treatment plan comparisons. Material and methods. Helica
MADEIRA was a Collaborative Project cofunded by the European Commission through the EURATOM Seventh Research Framework Programme. It was structured into four scientific work packages, and its aim was to optimize the efficacy and safety of 3D functional imaging in nuclear medicine and thereby to reduce the radiation exposures of the patients while keeping or even improving the quality of the diagno
In this work we investigate the interplay between flow and boundary condition effects on the orientation field of a thermotropic nematic liquid crystal under flow and confinement in a microfluidic device. Two types of experiments were performed using synchrotron small-angle X-ray-scattering (SAXS). In the first, a nematic liquid crystal flows through a square-channel cross section at varying flow
The increased demand for clean power in recent years has led to the development of various processes that include different types of CO2 capture. Several options are possible: pre-combustion concepts (fuel de-carbonization and subsequent combustion of H2), post-combustion concepts (tail-end CO2 capture solutions, such as amine scrubbing), and integrated concepts in which combustion is carried out
In this paper we propose apractical and efficient method for finding the globally optimal solution to the problem of camera pose estimation for calibrated cameras. While traditional methods may get trapped in local minima, due to the non-convexity of the problem, we have developed an approach that guarantees global optimality. The scheme is based on ideas from global optimization theory, in partic
This book, which is the result of my work within the project Conversion and Change of Confession, deals with Catholic mission and conversion in Scandinavia in the 19th and 20th cetries. I focus on Denmark, but the Danish situation is studied in a comparative Nordic pespective and against the background of the general religious, ideological and church-political development at the time. Up to the Se
After the discovery of space masers based on OH radicals (Weaver et al.cite{Wea65}) and H2O (Cheung et al. cite{Che69}) such microwavelasers have been found to work in more than 100 molecular species(Elitzur cite{Eli92}; Townes cite{Tow97}), as well as in highlyexcited H atoms (Strelnitski et al. cite{Str96}). In the IR region (10mum), the effect of stimulated emission of radiation in t
Context/Objective: To effectively normalize IGF-I in patients with acromegaly, various covariates may affect dosing and plasma concentrations of pegvisomant. We assessed whether sex, age, weight, and previous radiotherapy influence dosing of pegvisomant in patients with active disease. Design: Data from 69 men and 49 women participating in multicenter, open-label trials of pegvisomant were retrosp
Purpose: Free prostate specific antigen (PSA) in serum consists of heterogeneous molecular subforms. Recently we developed an immunoassay for selective measurement of a subfraction of free PSA called intact PSA, which has been shown to be closely associated with prostate cancer. We assessed the ability of serum intact PSA to discriminate between benign and malignant prostatic disease. Materials an
We here report the synthesis of the two polyamine-based nucleoside derivatives 5-{[bis-(3-aminopropyl)amino]acetamido-1-propynyl}uridine and 2-{[bis-(3-aminopropyl)amino]-acetamido-1-propynyl}adenosine. The various polyamine derivatives have been used in thermal melting analysis using DNA from herring testes, and in cellular studies using four different cell lines. The compounds were all found to
Popular Abstract in Swedish En av de viktigaste frågeställningarna inom molekylär genetik är hur uttrycket av människans ca 30-40 000 gener regleras i tid och rum. En typ av reglering som är väldigt viktig är transkriptionell reglering och denna utövas av proteiner som kallas transkriptionsfaktorer. Dessa binder till specifika områden i DNA strängarna i närheten av genkodande regioner och kan däriNeuroblastoma is a childhood tumor derived from primordial neural crest cells. The tumor cells exhibit a phenotype similar to that of developing neuroblasts, which indicates that the tumor arises due to perturbed differentiation of the sympathetic nervous system. It is well established that transcription factors control the steps leading to neuronal differentiation, and a number of basic helix-loo
Popular Abstract in Swedish De flesta komponenter som används i vårt samhälle har genomgått en bearbetningsprocess i något skede i sin tillverkningscykel. På grund av detta spelar de ekonomiska aspekterna av bearbetningsprocessen en viktig roll i tillverkningskostnaden. Det finns flera skäl till att utveckla ett rationellt förhållningssätt till skärande bearbetning, såsom att förbättra skärteknik,Most components in use in our society have undergone a machining process at some stage within its manufacturing cycle. As a result, the economics of the machining process plays an important role in the manufacturing costs. There are several reasons for developing a rational approach to material removal, such as improving cutting techniques, producing products with enhanced precision, and increasin
Capacitive binding assays have long been considered highly sensitive. The underlying method in such assays includes sending short potential pulses and then registering the current. However, with the introduction of current pulses and registration of potential responses, the stability improved significantly, leading to assays of extreme sensitivities. The new assaying technology has been applied in
The beach topography change in the nearshore zone may be induced by natural phenomena such as wind, wave, storm, tsunami, and sea level rise. However, it can also be caused by man-made structures and activities, for example, groins, detached breakwaters, seawalls, dredging, and beach nourishment. Therefore, understanding the beach topography evolution in this zone is necessary and important for co
A study was undertaken to measure the effects of conspecific density on the growth, mortality and deformity rate of yellowtail kingfish Seriola lalandi Valenciennes during the first feeding period. Newly hatched larvae were stocked in replicate tanks at initial densities of 40, 60 and 100 ind. l(-1) until 30 d post-hatch (DPH). Live prey was administered at frequent intervals in an effort to maint
Three-dimensional (3-D) delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) helps quantify biochemical changes in articular cartilage that correlate with early-stage osteoarthritis. However, dGEMRIC analysis is performed slice by slice, limiting the potential of 3-D data to give an overall impression of cartilage biochemistry. We previously developed a computational algorithm to produce unfolde
Background: We analyzed the hypoallergenic potential of a recently bred apple selection with unusually low content of Mal d 1, using an oral challenge model with three additional apple cultivars for comparison. Methods: Sixty-six birch pollen-allergic individuals with a history of oral allergy syndrome after apple intake were subjected to a double-blind oral provocation with two apple cultivars (B
