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Ribonucleases and host defense: identification, localization and gene expression in adherent monocytes in vitro

Several ribonucleases of the RNase A family function as antibacterial, anti-parasitic and anti-viral agents. In this work, we have shown that mRNAs encoding five of the six known human ribonucleases of the RNase A family are expressed in cultured human monocytes, and that ribonucleases are released by adherent monocytes in culture. Using a polyclonal antiserum prepared against recombinant protein,

Antibody responses to borrelia IR6 peptide variants and the C6 peptide in Swedish patients with erythema migrans

The aim of this study was to evaluate the antibody responses to different VIsE protein IR6 peptide variants and the synthetic C6 peptide in acute and convalescent (2-3 and 6 months) serum samples from Swedish patients with clinical erythema migrans (EM). Serum samples were prospectively collected from 148 patients with EM and compared to serum samples obtained from 200 healthy blood donors. The Ig

Early- versus Late-Onset Alzheimer’s Disease—Differences in Functional Impairment.

Background: Persons with clinical onset of Alzheimer’s disease (AD) before 65 years of age are diagnosed with early-onset AD (EOAD). The prevalence of EOAD is low, but varies among studies from 6% to 16%. Most individuals with EOAD are still working, have an active social life, and might have children living at home. Therefore, the consequences of being diagnosed early with a disease that implies

Subjective rhythmization : A replication and an assessment of two theoretical explanations

Subjective rhythmization is that phenomenon whereby, when one is listening to a monotone metronome sequence, some sounds are experienced as accented. These subjectively accented sounds group the sequence similarly to how the metrical structure of a piece of music groups the beats. Subjective rhythmization was first investigated by Bolton (1894); the present study aims at replicating and extending

Strategic management - An online collaboration between two class groups separated by a "small pond" and six time zones

An undergraduate course in Strategic Management seemingly provides similar basic content to students including the infamous SWOT (strengths, weaknesses, opportunities and threat) analysis along with the identification of functional level, business level, and generic strategies to enhance an organization’s competitiveness. One of the most common resources for this type of course is the article outl

Mycket mat, men lite måltider : En studie av arbetsplatsen som måltidsarena

Popular Abstract in Swedish Många människor tillbringar en stor del av dygnet på en arbetsplats, vilket innebär att det är en plats och en tid inte bara för arbete utan också för sociala relationer samt för mat och dryck. Maten, vare sig det handlar om lunchen klockan tolv, eftermiddagsfikan klockan tre eller chokladbiten under nattskiftet, bidrar till att skapa pauser i arbetet. Arbetsplatsen kanMany people spend hours in a workplace every week and food and drink play a central role in providing nutrition and energy and help to create breaks during the working day. However, meals are something more than the food consumed. This dissertation focuses on the meal at work, where the meal is surrounded by special circumstances when it comes to time, place and social relations, as well as the fo

Memory distorions resulting from a choice blindness task

Using a choice blindness paradigm, it is possible to switch decisions and outcomes in simple choice tasks. Such switches have been found to carry over into later choices, hypothesized to be mediated by beliefs about earlier decisions. Here we investigated participants’ memories for stimuli in a simple choice blindness task involving preferential choices between pairs of faces. We probed participan

Digital Consumption and Over-Indebtedness Among Young Adults in Sweden

This LUii report presents empirical results from studies on consumption and over-indebtedness in Swedish young adults in a digital context. The studies have been conducted through in-depth interviews with municipal financial counsellors as well as a quantitative survey with approximately 1,100 respondents in a sample representative of Swedes from 18 to 25 years old. The report includes an extensiv

Molecular correlates for maximal oxygen uptake (VO2max) and type 1 fibers.

Maximal oxygen uptake (VO2max) and the amount of type 1 fibers are interrelated but the underlying unifying molecular mechanisms are poorly understood. To explore these mechanisms we related gene expression profiles in skeletal muscle biopsies of 43 age-matched men from published datasets with VO2max and amount of type 1 fibers and replicated some of the findings in muscle biopsies from 154 young

A systematic review of studies in the contributions of the work environment to ischaemic heart disease development

BACKGROUND: There is need for an updated systematic review of associations between occupational exposures and ischaemic heart disease (IHD), using the GRADE system.METHODS: Inclusion criteria: (i) publication in English in peer-reviewed journal between 1985 and 2014, (ii) quantified relationship between occupational exposure (psychosocial, organizational, physical and other ergonomic job factors)

From data to decision - learning by probabilistic risk analysis of biological invasions

Predicting an uncertain future with uncertain knowledge is a challenge. The success of efforts to preserve biodiversity, to maintain biosecurity and to reduce a negative impact from climate change, depend on scientifically based predictions of future events. The ongoing introduction of non-indigenous species threatens ecological systems for which empirical data is sparse and scientific knowledge i

Innovations and social problem solving: A comparative study

This article explores the practical implementation of two innovative projects in Denmark and Sweden. The research is motivated by the high political interest for innovations as a modern quick fix to societal problems. Innovations are regarded as an all-round solution; however, research has mainly been focused on technical and economical factors without considering social problem solving. Utilizing

Predictions of temperature and pressure fields due to collapse of a bubble in sulfuric acid solution under ultrasound

A gas bubble under the influence of an ultrasonic field so strong to destroy any material due to high pressures and temperatures reached during the collapse is the topic of the present paper. In the current work, simulations have been performed to describe the radial dynamics of a gas (argon) bubble being strongly forced to periodic oscillation in a highly viscous liquid like aqueous sulfuric acid

Critical levels of atmospheric pollution: criteria and concepts for operational modelling of mercury in forests and lake ecosystems.

Mercury (Hg) is regarded as a major environmental concern in many regions, traditionally because of high concentrations in freshwater fish, and now also because of potential toxic effects on soil microflora. The predominant source of Hg in most watersheds is atmospheric deposition, which has increased 2- to >20-fold over the past centuries. A promising approach for supporting current European effo

Supply chain integration and performance: a review of the evidence

Purpose
The purpose of this paper is to analyse papers studying the link between supply chain integration (SCI) and performance, and to discuss reported empirical evidence relating to this fundamental question for logistics and supply chain management.

Design/methodology/approach
A systematic analysis of 38 papers published in nine important journals in logistics, su

Predicting 5-year outcome in first-episode psychosis: Construction of a prognostic rating scale

Objective: The aim of this study was to construct a rating scale to predict long-term outcome on the basis of clinical and sociodemographic characteristics in patients with symptoms of psychosis who seek psychiatric help for the first time. Method: Patients (N = 153) experiencing their first episode of psychosis (DSM-IV schizophrenia, schizophreniform disorder, schizoaffective disorder, brief psyc