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Effect of cavity geometry on fuel transport and mixing processes in a scramjet combustor

This paper reports a numerical investigation on the effect of cavity geometry on fuel transport and mixing processes in a scramjet combustor with a single rear-wall-expansion cavity. The numerical solver and the LES methods were validated against available experimental data and the numerical results were shown in good agreement with the experiments. Effect of the cavity rear wall height on the non

Critical Care Management after Cardiac Arrest

Sudden cardiac arrest is a devastating event with high mortality and substantial morbidity among survivors. Early recognition and intervention to restore circulation is the primary goal; once that is achieved, the path toward a meaningful recovery starts. Initial in-hospital care is focused on emergency cardiac care, but soon there is a change to a more brain-oriented critical care including targe

Strategy for predicting railway-induced vibrations in buildings

Urban densification is a way of accommodating population growth. Land adjacent to railways is used for constructing residences and other buildings, and new tramway systems are planned. Under these circumstances, nearby buildings will be exposed to vibrations and noise that may become a nuisance for the residents. It is necessary, even at an early stage of planning, to assess the extent of the vibr

The Future of U.S. Public Diplomacy: An Uncertain Fate, Kathy R. Fitzpatrick

‘The Future of U.S. Public Diplomacy’ is a welcome addition to critical studies within the field of public diplomacy (PD) by public relations (PR) scholar Kathy Fitzpatrick. The monograph aims to untangle many of PD’s historical misconceptions and contribute to the development of its conceptual foundations through an examination of the U.S. experience. In truth, the interaction between the discuss

The Revised Sunspot Record in Comparison to Cosmogenic Radionuclide-Based Solar Activity Reconstructions

Recent revisions in the sunspot records illustrate the challenges related to obtaining a 400-year-long observational record of past solar-activity changes. Cosmogenic radionuclides offer the possibility of obtaining an alternative and completely independent record of solar variability. Here, we illustrate that these records offer great potential for quantitative solar-activity reconstructions far

A retrospective analysis of hand tapping as a longitudinal marker of disease progression in Huntington's disease

BACKGROUND: Current clinical assessments of motor function in Huntington's Disease (HD) rely on subjective ratings such as the Unified Huntington's Disease Rating scale (UHDRS). The ability to track disease progression using simple, objective, inexpensive, and robust measures would be beneficial.METHODS: One objective measure of motor performance is hand-tapping. Over the last 14 years we have rou

An Experimental Data-Set on Pre-school Children Evacuation

This study presents an experimental data-set describing movement and behaviours of pre-school children. Data is presented together with detailed information about the evacuation procedure and the data collection methods, in order to enable a comprehensive interpretation of the results and to enhance the understanding of pre-school children evacuation. Data was collected during two semi-announced e

Regional differences in air velocity of microclimate inside clothing and bellows effect

Despite of a crucial role of microclimate inside clothing in thermal comfort, air velocity inside clothing has been hardly reported, ever since Lewis et al (1969) demonstrated that air velocity of the still air layer on the naked human body was 0.25 m/s using colour schlieren cinephotography. This study was aimed to investigate the air velocity of microenvironment inside clothing and the bellows e

Cancer risks associated with germline PALB2 pathogenic variants : An international study of 524 families

PURPOSE To estimate age-specific relative and absolute cancer risks of breast cancer and to estimate risks of ovarian, pancreatic, male breast, prostate, and colorectal cancers associated with germline PALB2 pathogenic variants (PVs) because these risks have not been extensively characterized. METHODS We analyzed data from 524 families with PALB2 PVs from 21 countries. Complex segregation analysis

PD-L1 Testing in Cytological Non-Small Cell Lung Cancer Specimens : A Comparison with Biopsies and Review of the Literature

INTRODUCTION: Programmed death-ligand 1 (PD-L1) expression is used for treatment prediction in non-small cell lung cancer (NSCLC). While cytology may be the only available material in the routine clinical setting, testing in clinical trials has mainly been based on biopsies.METHODS: We included 2 retrospective cohorts of paired, concurrently sampled, cytological specimens and biopsies. Also, the l

Assessing the potential and hydrological usefulness of the CHIRPS precipitation dataset over a complex topography in Pakistan

This study evaluates the spatial and temporal performance of the Climate Hazard Group InfraRed Precipitation Satellite (CHIRPS) against Tropical Rainfall Measuring Mission (TRMM) Multi-Satellite Precipitation Analysis (TMPA) 3B42/3B43 v. 7 and Global Precipitation Measurement (GPM)-based Integrated Multi-Satellite Retrievals for GPM (IMERG V06), from 2000 to 2013. Several statistical metrics were

Matching experimental and three dimensional numerical models for structural vibration problems with uncertainties

The simulation model which examines the dynamic behavior of real structures needs to address the impact of uncertainty in both geometry and material parameters. This article investigates three-dimensional finite element models for structural dynamics problems with respect to both model and parameter uncertainties. The parameter uncertainties are determined via laboratory measurements on several be

Spectral induced polarization: frequency domain versus time domain laboratory data

Spectral information obtained from induced polarization (IP) measurements can be used in a variety of applications and is often gathered in frequency domain (FD) at the laboratory scale. In contrast, field IP measurements are mostly done in time domain (TD). Theoretically, the spectral content from both domains should be similar. In practice, they are often different, mainly due to instrumental res

Tapering of prescribed opioids in patients with long-term non-malignant pain (TOPIO)-efficacy and effects on pain, pain cognitions, and quality of life : a study protocol for a randomized controlled clinical trial with a 12-month follow-up

BACKGROUND: Opioids are still widely prescribed to long-term pain patients although they are no longer recommended for long-term treatments due to poor evidence for long-term efficacy, risks of serious side effects, and the possibility of inducing opioid hyperalgesia. In a Cochrane study from 2017, the authors identified an urgent need for more randomized controlled trials investigating the effici

Measurements of the inclusive and differential production cross sections of a top-quark–antiquark pair in association with a Z boson at √s=13 TeV with the ATLAS detector

Measurements of both the inclusive and differential production cross sections of a top-quark–antiquark pair in association with a Z boson (tt¯ Z) are presented. The measurements are performed by targeting final states with three or four isolated leptons (electrons or muons) and are based on s=13 TeV proton–proton collision data with an integrated luminosity of 139 fb - 1, recorded from 2015 to 201

SIP laboratory data: frequency-domain versus time-domain

Spectral information from induced polarisation (IP) measurements can be used for several applications as the characterisation of the lithology, the estimation of hydraulic parameters, the localization of contaminated areas and many more.So far, the spectral content has been mainly determined in frequency domain (FD). Due to significant instrumental developments and advanced data processing and inv

Quantification of the absorption and scattering effects of diffusers in a room with absorbent ceiling

In ordinary public rooms, such as classrooms and offices, an absorbent ceiling is the typical first acoustic action. This treatment provides a good acoustic baseline. However, an improvement of specific room acoustic parameters, operating for specific frequencies, can be needed. It has been seen that diffusing elements can be effective additional treatment. In order to choose the right design, pla

Modeling symbiotic biological nitrogen fixation in grain legumes globally with LPJ-GUESS (v4.0, r10285)

Biological nitrogen fixation (BNF) from grain legumes is of significant importance in global agricultural ecosystems. Crops with BNF capability are expected to support the need to increase food production while reducing nitrogen (N) fertilizer input for agricultural sustainability, but quantification of N fixing rates and BNF crop yields remains inadequate on a global scale. Here we incorporate tw

Bioavailability of stream dissolved organic carbon (DOC) during spring flood and base flow in high-latitude streams

An important component of the carbon cycle is the lateral flow of dissolved organic carbon (DOC) from terrestrial ecosystems to streams and rivers. The fate of this carbon depends very much on the bioavailability of DOC (BDOC), which may determine whether DOC is returned to the atmosphere as CO2 or deposited in sediments. This study focuses on the linkages between stream DOC composition, optical c

HPI appraisal of concentrations of heavy metals in dynamic and static flow of Ganga River System

Ganga River system is a life support system to sustain the people of northeast region, India, by providing freshwater resource. In this study, the seasonal heavy metal concentrations of Ganga River system at Haridwar region (India) have been characterised for metal pollution. The collection of water samples was done from 10 different locations and analysed for various metal parameters (Zn, Pb, Mn,