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Objective: To investigate perceptions of control among people with uncontrolled and well controlled type 2 diabetes (T2D) treated with basal insulin, as well as differences in perceptions and diabetes management practices between the two groups. Research design and methods: Web surveys of 1012 people with uncontrolled T2D (HbA1c >8.0% or 64 mmol/mol) on basal insulin in Sweden, Switzerland, and th

OBJECTIVES: To evaluate an objective and quantitative method for assessment of capillary abnormalities in systemic sclerosis (SSc).METHODS: Nailfold capillaries were investigated by capillary microscopy and photographed in 17 consecutive SSc patients (five with diffuse cutaneous systemic sclerosis (dSSc) and 12 with limited cutaneous systemic sclerosis (lSSc)) and in 17 healthy controls. Investiga

BACKGROUND AND PURPOSE: Genome-wide association (GWA) studies have identified a few risk loci for ischaemic stroke, but these variants explain only a small part of the genetic contribution to the disease. Coding variants associated with amino acid substitutions or premature termination of protein synthesis could have a large effect on disease risk. We performed an exome array analysis for ischaemi

Environmental impacts from passenger transportation continue to increase globally due to a rise in kilometers traveled and a shift to emission-intensive transportation modes (from public transportation and active modes such as walking and cycling to motorcycle and car ridership). The electrification of the passenger fleet, coupled with low-carbon energy sources, is expected to decrease some of the

As biological surfactants, bile salts (BSs), play important roles in biological processes, i.e., food digestion, but also in BS-related diseases, as well as in applications. In this thesis, the main focus was to gain a fundamental understanding of the intermolecular interactions between BSs and cationic block copolymers with the purpose of developing new BS sequestrants that are used in the treatm

Most stomatopod crustaceans have complex retinas in their compound eyes, with up to 16 spectral types of photoreceptors, but members of the superfamily Squilloidea have much simpler retinas, thought to contain a single photoreceptor spectral class. In the Atlantic stomatopod Squilla empusa, microspectrophotometry shows that all photoreceptors absorb light maximally at 517 nm, indicating that a sin

The coronavirus pandemic (COVID-19) is currently putting high pressure on most countries’ critical infrastructures (not only health care), creating huge uncertainties in supply and demand, and disrupting global supply chains. The global crisis will demonstrate the extent to which different parties (countries, public authorities, private companies etc.) can work together and take holistic decisions

In the search for viable pathways for transforming governance and institutions in the Rio+20 agenda,strengthening of public‐private governance networks has been emphasized. Important initiatives arefound in the expanding bioenergy sector where several certification schemes have been launched forensuring that bioenergy feedstock meet environmental and social requirements. These initiatives areencou

Buildings account for a signifi cant proportion of the energy use thatgenerates greenhouse gases and consequently drives the ongoing climatechange. As the population of the world increases, the need for buildingsincreases, while the energy use needs to decrease. A reduction in energyuse and increased use of renewable energy are important measures forclimate change mitigation. A fi rst step in decr

Background: Colorectal cancer screening programmes and uptake vary substantially across Europe. We aimed to compare changes over time in colorectal cancer incidence, mortality, and stage distribution in relation to colorectal cancer screening implementation in European countries. Methods: Data from nearly 3·1 million patients with colorectal cancer diagnosed from 2000 onwards (up to 2016 for most

Elastic fibers containing elastin play an important role in tendon functionality, but the knowledge on presence and function of elastin during tendon healing is limited. The aim of this study was to investigate elastin content and distribution in intact and healing Achilles tendons and to understand how elastin influence the viscoelastic properties of tendons. The right Achilles tendon was complet

Aim: The aim of this study is to evaluate the quality of data on endometrial (EC) and ovarian, fallopian tube, peritoneal, abdominal or pelvic cancers (OC) registered in the Swedish Quality Register of Gynecologic Cancer (SQRGC). Method: A random sample of 500 patients was identified in the SQRGC and their medical charts were reviewed for re-abstraction of 31 selected core variables by an independ

The evolutionary relationship between signals and animal senses has broad significance, with potential consequences for speciation, and for the efficacy and honesty of biological communication. Here we outline current understanding of the diversity of colour vision in two contrasting groups: the phylogenetically conservative birds, and the more variable butterflies. Evidence for coevolution of col

Background The impact of the prophylactic vaccine against human papillomavirus (HPV) types 6, 11, 16, and 18 (HPV6/11/16/18) on all HPV-associated genital disease was investigated in a population that approximates sexually naive women in that they were "negative to 14 HPV types" and in a mixed population of HPV-exposed and -unexposed women (intention-to-treat group). Methods This analysis studied

I enlighet med bestämmelserna i lagen om genetisk integritet m.m. är surrogatmoderskap inte tillåtet inom svensk hälso- och sjukvård. Vissa ofrivilligt barnlösa som saknar möjlighet till behandling med assisterad befruktning i Sverige, söker sig därför utomlands för att genomgå surrogatarrangemang. Svårigheter kan uppstå när de tilltänkta föräldrarna vill ta hem barnet till Sverige. Eftersom surroAccordning to the provisions of the Genetic Integrity Act, surrogacy is not permitted in the Swedish health care system. Thus some individuals who suffer from involuntary childlessness cannot be offered treatment of assisted reproduction in Sweden. Some of them travel abroad to undergo surrogate arrangements. When the prospective parents wish to bring their child home difficulties arise. Due to th

OECD introduced 15 Action plans as part of the BEPS-project in 2014 in their work to combat base erosion and profit shifting (BEPS). Action plan 13 provides for a re-examined transfer pricing documentation and a new Country-by-country-reporting. The CbC-reporting is to be included in a three-tired approach including a master-file and a local-file. This thesis will focus on Action plan 13 in the li

I en rättegångsprocess är olika uppgifter fördelade mellan de olika aktörerna. Huvudregeln enligt svensk rätt är att parterna har huvudansvaret för den materiella delen av processen, medan domstolen ansvarar för den formella delen. Det har sin grund i de processrättsliga principer som reglerar ansvaret mellan domstolen och parterna i rättegångsprocessen: den kontradiktoriska principen, förhandlingIn a proceeding in court, different tasks are divided between the different actors. The main principle in Swedish law is that the litigants have the responsibility for the substantive part of the proceeding, while the court is responsible for the formal part. This is based on the procedural code principles that regulate the responsibility between the court and the litigants in the court proceeding

This research investigates the contribution of local currencies to sustainability. I look at a specific local currency scheme (the Bristol Pound, in Bristol, United Kingdom) through a transitions perspective, employing a Transitions Evaluation Framework, Multi-Level and Multi-Phase Perspectives to conduct my analysis. I use a qualitative triangulation approach to collect data, namely semi-structur

Syftet med studien var att utifrån en kvalitativ ansats undersöka högstadielärares motivation i deras dagliga arbete. I undersökningen har lärarna fått reflektera och berätta om sin självupplevda motivation, hur de upplever sina arbetsuppgifter och hur deras yrke påverkar dem personligen. Undersökningen har gett en djup bild av lärarnas egna upplevelser av sin arbetssituation. Genom semistrukturerThe purpose of this study was to examine motivation of high school teachers in their daily work. The teachers in the study have been given an opportunity to reflect and describe their work motivation, how they experience their work and how their profession affects them personally. The survey has given a deep picture of the teachers' own experiences of their work situation. Through semi-structu