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Surgical staff is considered to have several ergonomic risk factors, but their physical workload and musculoskeletal health have seldom been evaluated. Clinical examinations of neck and upper extremities were performed in 99 theatre nurses and 93 assisting nurses, all females. Their physical workload was assessed by questionnaire, and by technical measurements of postures, movements and muscular l
‘The model of crisis’ is a culturally shared and widespread idea of human reactions to a number of misfortunes, such as accidents, diagnosis of disease, divorces, becoming a parent of a disabled child, etc. The crisis model conveys the idea of coming to terms with unwanted experiences while advancing through different “phases”, for example phases of “denial”, “processing”, and “acceptance”. The
To better understand and characterize chromosomal structural variation during breast cancer progression, we enumerated chromosomal rearrangements for 11 patients by performing low-coverage whole-genome sequencing of 11 primary breast tumors and their 13 matched distant metastases. The tumor genomes harbored a median of 85 (range 18-404) rearrangements per tumor, with a median of 82 (26-310) in pri
ATP Binding Cassette B1 (ABCB1) is a transporter with a broad substrate specificity involved in the elimination of several carcinogens from the gut. Several polymorphic variants within the ABCB1 gene have been reported as modulators of ABCB1-mediated transport. We investigated the impact of ABCB1 genetic variants on colorectal cancer (CRC) risk. A hybrid tagging/functional approach was performed t
Both environmental and host factors influence risk of cutaneous melanoma (CM), and worldwide, the incidence varies depending on constitutional determinants of skin type and pigmentation, latitude, and patterns of sun exposure. We performed genetic analysis of CDKN2A, CDK4, BAP1, MC1R, and MITFp.E318K in Danish high-risk melanoma cases and found CDKN2A germline mutations in 11.3% of CM families wit
Diabetic patients have a much more widespread and aggressive form of atherosclerosis and therefore, higher risk for myocardial infarction, peripheral vascular disease and stroke, but the molecular mechanisms leading to accelerated damage are still unclear. Recently, we showed that hyperglycemia activates the transcription factor NFAT in the arterial wall, inducing the expression of the pro-atheros
Popular Abstract in Swedish 1997 ökade långtidssjukskrivningarna i Sverige, vilka fortsatte att öka till och med 2002. Vanligtvis förklaras ökningen med orsaker på individnivå eller i arbetsmiljön. Genom att avgränsa avhandlingen till långtidssjukskrivningar bland arbetslösa, hamnar en annan förståelse i fokus, sammanfattad som att välfärdsstater utvecklar dold arbetslöshet bland dem med begränsadIn 1997 the number of long-term absences due to illness began and continued to rise in Sweden. Traditional explanations of why this is so have been centered on either blaming the individual or blaming the work environment. By focusing on long-term illness of the unemployed, this dissertation suggests that there is a growing residual unemployment within advanced welfare states. The main question th
Popular Abstract in Swedish Enligt Världshälsoorganisationen (WHO) är en god hälsa ett "tillstånd av fullständigt fysiskt, socialt och mentalt välbefinnande, och inte enbart avsaknad av sjukdom eller funktionshinder". Vår hälsa påverkas under hela vår levnad av en mängd faktorer såsom exempelvis våra gener, biologiska faktorer, sociodemografiska faktorer, beteendefaktorer och livsstil samt miljöfaAbstract: The complexity of health relates to the interplay between numerous factors, e.g., biological and genetic factors, sociodemographic factors, life-style, environmental factors as well as health care services, all possibly acting throughout the life-course. While earlier health theories mainly have focused on adult life style as causes of adult ill-health, life-course research has in recent
BACKGROUND: The aim of the study was to examine associations between intake of macronutrients and dietary fiber and incident ischemic cardiovascular disease (iCVD) in men and women. METHODS: We used data from 8,139 male and 12,535 female participants (aged 44-73 y) of the Swedish population-based Malmö Diet and Cancer cohort. The participants were without history of CVD and diabetes mellitus, and
Double emulsions have potential applications in the food, cosmetic and pharmaceutical industries as vehicles for encapsulation and delivery of nutrients during food digestion or as drug release. The major drawback of this type of emulsions is that they are often difficult to stabilize. Particle stabilized emulsions, known as Pickering emulsions, show special features, such as being extremely stabl
The small-wavector expansions for the first- and second-order exchange energy kernels (second-and third-order functional density derivatives of the exchange energy) have been investigated. Expansion coefficients are found, both in the case of a statically screened Coulomb interaction and a 'bare' interaction. The ensuing series of gradient corrections to the local density approximation (LDA) is th
The effect of severe insulin-induced hypoglycemia on the activity of the pyruvate dehydrogenase enzyme complex (PDHC) was investigated in homogenates of frozen rat cerebral cortex during burst suppression EEG, after 10, 30, and 60 min of isoelectric EEG, and after 30 and 180 min and 24 h of recovery following 30 min of hypoglycemic coma. Changes in PDHC activity were correlated to levels of labile
Introduction: The clinical diagnosis of Parkinson’s disease (PD) is based on the identification of bradykinesia and at least one additional feature among rigidity, resting tremor and postural instability. These clinical features have been estimated to appear when at least 50% of the nigral dopamine neurons and 70% of putaminal dopamine tissue contents are lost [1]. Dopaminergic imaging suggests th
The ratio of the proton's elastic electromagnetic form factors, GEp/GMp, was obtained by measuring Pt and Pℓ, the transverse and the longitudinal recoil proton polarization, respectively. For elastic →ep→e→p, GEp/GMp is proportional to Pt/Pℓ. Simultaneous measurement of Pt and Pℓ in a polarimeter provides good control of the systematic uncertainty. The results for the ratio GEp/GMp show a systemat
Objective: The objective of this study was to compare short-term outcomes in patients who underwent thoracic endovascular aortic repair (TEVAR) with stent grafts alone or with a composite device design (stent graft plus bare-metal aortic stent) for acute type B aortic dissection in the setting of malperfusion. Methods: This retrospective analysis included patients with acute (≤14 days of symptom o
Aim: To explore the long-term learning process in movement awareness development supported by a video-based learning model. Participants: Eleven undergraduate nursing students. Method: The students participated in learning sessions comprising video modelling, video feedback and reflective enquiry with a focus on inter-personal interaction. Each student participated in three individual video sessio
Planetary boundaries are either being approached or already crossed, and there is no evidence for an absolute decoupling of GDP growth, resource use and greenhouse gas emissions. How economic and social systems may be reembedded into environmental limits in the absence of growth is a crucial issue within and beyond economics. This paper outlines some of the elements and analytical steps that may t
Nanowires (NWs) have the potential for a wide range of new optoelectronic applications. For example, light-emitting diodes that span over the whole visible spectrum are currently being developed from NWs to overcome the well known green gap problem. However, due to their small size, NW devices exhibit special properties that complicate their analysis, characterization, and further development. In
Wireless communication is evolving rapidly with ever more connected devicesand significantly increasing data rates. Since the invention of the smartphoneand the mass introduction of mobile apps, users demand more andmore traffic to stream music, watch high-definition video or to simply browsethe internet. This tremendous growth is more pronounced by the introductionof the Internet of Things (IoT)
