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C4b-binding protein (C4BP) is an important component in the regulation of the complement system and also binds the anticoagulant vitamin K-dependent protein S. These activities are performed by distinct, although structurally related, polypeptides of 70 kDa (alpha chain) and 45 kDa (beta chain), respectively. In this report we have investigated the genetic relationships between these polypeptides.
EU law increasingly requires that the Member States establish independent administrative bodies in various fields. Examples include market supervision, non-discrimination, and data protection. This article addresses the realisation of such requirements in the five Nordic states. The West Nordic systems of Denmark, Iceland, and Norway feature a traditional hierarchic organisation of the administrat
The identification of starting points for compound development is one of the key steps in early-stage drug discovery. Information-rich techniques such as crystallographic fragment screening can potentially increase the efficiency of this step by providing the structural information of the binding mode of the ligands in addition to the mere binding information. Here, we present the crystallographic
Stationary solar energy concentrators are a promising option for decreasing the price of photovoltaic electricity. This thesis studies stationary concentrators in PV/Thermal applications. The studied systems are parabolic troughs intended for building integration. The first chapters briefly explain the optics of solar energy concentrators. The theoretical maximum concentration ratios of two and th
In the debate on how to make democracy strong against terrorism, it has been suggested that the Western democracies need new protective measures. This paper argues that, far from protecting democracy, such measures may in fact undermine the very values and virtues that make democracy possible. Information freedom, the right to due process and the protection of privacy are all fundamental for the
Since the 1990s, it has often been argued that the earth is like an island in space and that its brittleness is most clearly reflected on small islands in the oceans. Easter Island, for instance, with its largely depleted resources and an indigenous population which almost became extinct in the 19th century, has been seen as a microcosmic warning about what may happen to our entire planet. However
Although a substantial body of theoretical as well as empirical work emphasizes the role of the mass media in constructing what could serve as a political public sphere at the European level, strikingly little is known, in qualitative terms, about opinion-making journalists’ underlying views and orientations on the European integration process. The point of departure in the present paper is that o
In the cinemas of small European nations, infrastructural support systems aimed at endorsing and strengthening audiovisual production, tend to play an increasingly pivotal role. Since additional systems have been added, with the intent to, for instance, encourage co-production or to attract filming and post-production work to assorted places – and always coming with various provisions attached – o
This study aimed to deepen and refine the understanding of the responsibility burden that children may need to navigate in a family where a parent is grappling with alcohol abuse. Our research questions included “How is the responsibility that a child may need to assume for a parent with alcohol abuse portrayed in the autobiographies of adult children?” and “How is the responsibility one may need
This project presents the design and development of “Breathe Right,” a wearable AI-powered device and app aimed at promoting a regulated and healthy breathing pattern. Our breathing pattern plays a significant role in both our physical and mental health. Even if we don’t realize it, there are proper and improper ways to breathe, and an unregulated breathing pattern can unconsciously harm our healt
Inverse problems are important in quantum physics as their solutions are essential in order to describe a number of systems using measurable information, e.g. excitation energies or material properties. The problem with inverse problems is that they are usually very hard to solve. One method that could be useful in solving these problems is artificial neural networks. Artificial neural networks ha
Over the past few decades, employee engagement has been increasingly recognised as a key driver of organisational success. Although previous research has examined psychological and organisational factors influencing engagement, few studies have examined how it varies over time. This study explores the dynamic and sustainable aspects of employee engagement in Swedish organisations, focusing on how
To simulate subcutaneous injection pressure, numerical solvers are developed and subsequently used to train a predictive, data-driven surrogate model that delivers fast and reliable outputs. Different approaches are examined for solving a nonlinear partial differential equation that describes the pressure during subcutaneous injections over time and in a semi-infinite spatial domain. For the spati
In a time where peer-to-peer networks, often with previously unconnected devices, are increasing in relevance, new storage solutions are needed. Storage can no longer rely on a single central entity but rather needs to depend on the resources of the entire network. Such a solution is the distributed hash table (DHT) which allows distributed storage of resources, ensuring redundancy and availabilit
This thesis attempts to study and explain Swedish school principals’ reactions to and perceptions of the auditing process of the Swedish School Inspectorate. Guided by two strands of institutional theory, rational choice and sociological institutionalism, the author identifies certain factors that can potentially affect how principals react and think about the auditing process. The study follows a
