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BACKGROUND: Endocrine resistance is a major obstacle to optimal treatment effect in breast cancer. Some genetic markers have been proposed to predict response to aromatase inhibitors (AIs) but the data is insufficient. The aim of the study was to find new genetic treatment predictive markers of AIs.METHODS: The ongoing population-based BC-blood study in Lund, Sweden includes women with primary bre

INTRODUCTION: Impaired renal function as seen in chronic kidney disease (CKD) is a known risk factor for coronary artery diseases and has been linked to inferior outcome after myocardial revascularization. Studies on the outcome of coronary bypass grafting (CABG) in CKD-patients are scarce. We aimed to study this subgroup of patients following CABG in a well defined whole-nation cohort, focusing o

The Exhibition Notes installation includes Blind Volumes (2016/2022), a work that uses steel frames as a support, a kind of stage on which films and kinetic sculptures are displayed. Eight further artworks are choreographed around the gallery, transforming it into a place for experimentation. The gallery thus becomes a space where the constitutive elements of film, celluloid, projector and sound a

There was a widespread euphoria in the 1990s in Uzbekistan and other post-Soviet societies at the prospect that introducing Western-style public administration (PA) institutions and traditions would play a pivotal role in promoting the rule of law and democratisation. Like other newly independent post-Soviet states, Uzbekistan has become a “laboratory” for testing various global (Western) PA model

Large amounts of cellulose-based waste textiles are generated every year, yet little is done to recycle this waste. Alternatives such as fiber-to-fiber recycling, where a significant part of the value of the waste textiles is recovered, are attractive possibilities. In this study, we have investigated the viability of using hydrated zinc chloride (ZnCl2·4H2O) as a solvent and swelling agent to con

Proton scattering has been applied to the problem of elemental quantitative analysis of air particulate matter. Elements up through chlorine may be resolved using 16 MeV protons incident upon targets up to about 1 mg/cm2 in thickness. Using the FSU Super FM Tandem Accelerator and a large area solid state proton detector, an analysis can be performed in several minutes. Combination of this techniqu

Therapeutic peptides can often not be formulated as tablets by themselves as they’re prone to enzyme degradation the oral route - they also do not present good enough passage through epithelial cells to be viable for this dosage form. But if formulated together with surfactants, e.g., sodium caprate (C10), the absorption through epithelial cells can be increased. When peptides and absorption enhan

En delägare som innehar kvalificerade andelar i ett fåmansföretag omfattas av de s.k. 3:12-reglerna som innebär att utdelning och kapitalvinst till viss del ska beskattas i inkomstslaget tjänst i stället för i inkomstslaget kapital. Om delägaren ska överlåta företaget kan han eller hon inom lagens gränser vidta en rad åtgärder för minska och senarelägga skatten som ska betalas för kapitalvinsten. A shareholder who holds qualified shares in a closely held company is subject to a special set of tax rules named the 3:12 rules. These rules lead to shareholders’ dividends and capital gains to some degree being taxed as labor income instead of capital income. If the shareholder should transfer the company, it is possible – within the boundaries of the law – to make some arrangements to reduce an

The aim of this study was to examine how organisations present their arguments regarding international homosexual adoption. The material of this study consisted of texts and the analysis have been based on the arguments from referral responses regarding the bill SOU 2001:10 (Children in homosexual families). Four themes were identified that seemed to pay a significant role in discussion of the iss

The aim of this study was to gain a deeper understanding of how close relatives experience living with a person with mental illness. The focus of this study was how the relative is affected, the support they receive from the surrounding system, and what strategies they develop to manage the situation. To answer the questions of the study, we have used qualitative content analysis on six autobiogra

In this essay the Swedish euthanasia debate was studied. The main focus of the study was to investigate the arguments presented in the debate to try to understand what kind of perspectives laid as a foundation of these arguments. The study shows that the arguments that favour euthanasia often come from the perspective of individual right to value their own lives, and use a democratic perspective,

Skåne faces great challenges for young people entering the labour market. The challenges include problems for unemployed and employers to meet. Furthermore, another challenge is all about low educational tradition. Last year (2015) Region Skåne started up a project called 1+1=3, where the aim is to work between administrations to get a better overview on how to tackle the challenges. This study is

Background: Many children undergo various surgeries, which often lead to acute postoperative pain. This pain influences recovery and quality of life. Non-steroidal anti-inflammatory drugs (NSAIDs), specifically cyclo-oxygenase (COX) inhibitors such as diclofenac, can be used to treat pain and reduce inflammation. There is uncertainty regarding diclofenac's benefits and harms compared to placebo or