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Objective: Meniscal calcifications are associated with the pathogenesis of knee osteoarthritis (OA). We propose a micro-computed tomography (μCT) based 3D analysis of meniscal calcifications ex vivo, including a new grading system. Method: Human medial and lateral menisci were obtained from 10 patients having total knee replacement for medial compartment OA and 10 deceased donors without knee OA (

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Haemophilia B (HB) is a rare inherited bleeding disorder caused by the deficiency of coagulation factor IX (FIX). The major clinical issues are bleedings, often targeting the joints, and the development of neutralising antibodies, i.e. inhibitors, to the FIX replacement therapy. Historically HB has been seen as identical to the more common haemophilia A (HA), i.e. deficiency of coagulation factor

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CONTEXT: Prostate cancer is a molecularly heterogeneous disease that is amenable to diagnostic testing to identify patients potentially eligible for personalised treatments inform familial risk and provide relevant information about potential prognosis. Several guidelines support the integration of genomic testing in a shared decision-making framework so that both health care professionals (HCPs)

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Children who are placed in foster care because of neglect or abuse have the right to maintain the relationship with their parents, as per the Swedish LVU law, though this is more often than not a complex feat to achieve. The Convention on the Rights of the Child states that children who are capable of forming their views shall be given the right to express those views freely in all matters affecti

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A commonly discussed issue among professionals in human service occupations, such as healthcare workers and social workers, is Secondary Traumatic Stress (STS). This phenomenon occurs when one is exposed to others' trauma and, in turn, becomes secondarily traumatized. The risk of experiencing STS can be reduced through strong organizational support combined with various strategies that individ

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Utifrån rättsdogmatisk metod har uppsatsen formulerat vilka de rättsliga definitionerna av nödvärnsrätten och envarsgripande är, problematiserat vilka problem som kan uppstå och var gränserna går. Jag har vidare tittat på samhällsstrukturers uppkomst, härledningar och definitioner. Även vad som är önskvärt och vad konsekvenserna blir när de inte överensstämmer med medborgares allmänna rättsmedvetaBased on legal-judicial methodology, the essay has formulated what the legal definitions of the right of self-defense and citizen’s arrest are, problematized which problems that can arise and where the lines are drawn. I have looked at what is desirable and what the consequences may be when they do not comply with the general publics sense of justice. I have especially looked at the possible emerg

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α-CGRP 8-37 is a peptide fragment of calcitonin gene-related peptide and is commonly used as a CGRP antagonist in pharmacological research. CGRP signaling has been discussed in relation to neuroimmune mechanisms in psoriasis, but a practical development of α-CGRP 8-37 requires analytical methods and formulation strategies that can handle peptide instability, adsorption, and matrix effects. The aim

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This study aimed to find and explore potential relations between the consumption of news on social media and psychological distress in young adults through the term news-related posts on social media. This quantitative survey study utilized a sample consisting of 337 students aged between 18 and 30 studying in Lund, Sweden. Information concerning daily news-related social media posts consumption a

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SUMMARYThe transcriptional regulator NrdR is present in most bacteria and in some archaea, but is lacking in eukaryotes. It controls the expression of operons of the universal and essential ribonucleotide reductase (RNR) enzymes, which provide building blocks of DNA by reducing ribonucleotides to their corresponding deoxyribonucleotides. The NrdR protein consists of an N-terminal zinc-ribbon domai

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Globalization is a widespread phenomenon that is having a strong influence on the modern society, creating both threats and opportunities. One of the most affected areas by the global pressures is the labor market, which requires specific policies and tools to respond to the increasing challenges. It is thus the task of the modern welfare states, to intervene in the attempt of transforming the glo

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The aim of the study was to complement dual labor market research by qualitatively exploring how labor market segmentations may be understood beyond sociodemographics or inequalities of job quality. By interviewing 12 Swedish workers with wage subsidies I have found that access to high job quality may facilitate trajectories towards primary market sectors, but they are only relevant so far as the

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Denna studie syftade till att utforska hur personal inom psykiatri och socialpsykiatri upplever (1) att de använder egna erfarenheter av psykisk ohälsa i sitt arbete (2) olika faktorer som påverkar detta användande. Detta undersöktes med hjälp av semistrukturerade intervjuer, vilka analyserades utifrån tematisk analys med utgångspunkt i aletisk hermeneutik. Elva behandlare med varierande yrkestillThe purpose of this study was to explore how staff in mental health care experience (1) using personal experiences of mental ill health in their work (2) different factors affecting this usage. This was explored using semi-structured interviews, which were analyzed using thematic analysis based on aletic hermeneutics. Eleven staff members in various professions were included. The analysis resulted