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OBJECTIVE: To determine factors associated with outcomes following pelvic exenteration for advanced nonrectal pelvic malignancy.BACKGROUND: The PelvEx Collaborative provides large volume data from specialist centers to ascertain factors associated with improved outcomes.METHODS: Consecutive patients who underwent pelvic exenteration for nonrectal pelvic malignancy between 2006 and 2017 were identi
Understanding the electronic structure and chemical bonding of transition metal complexes is important for improving the function of molecular photosensitizers and catalysts. We have utilized X-ray absorption spectroscopy (XAS) and resonant inelastic X-ray scattering (RIXS) at the Fe L3 edge to investigate the electronic structure of two Fe N-heterocyclic carbene complexes with similar chemical st
Background: The Clubfoot Assessment Protocol (CAP)is a multi dimensional instrument designed for longitudinal follow up of the clubfoot deformity during growth. Item reliability has shown to be sufficient. In this article the CAP's validity and responsiveness is studied using the Dimeglio classification scoring as a gold standard. Methods: Thirty-two children with 45 congenital c
Purpose: The research community has focused on defining reliable biomarkers for the early detection of the pathological hallmarks of Alzheimer’s disease (AD). In 2017, the Geneva AD Biomarker Roadmap initiative adapted the framework for the systematic validation of oncological biomarkers to AD, with the aim to accelerate their development and implementation in clinical practice. The aim of this wo
Objective: To estimate the genetic contribution to traumatic and degenerative meniscus tears for men and women across the lifespan. Methods: We linked the Swedish Twin Register with individual-level national healthcare data to form a 30-year, population-wide, longitudinal twin cohort. To study genetic contribution to meniscus tears, we estimated the heritability and familial risk using incident tr
This paper addresses the problem of distributed Kalman filtering, with focus on limiting the required communication bandwidth. By distributed we refer to a scenario when all nodes in the network desire an estimate of the full state of the observed system and there is no centralized computation center. Communication only takes place between neighbors and only a fixed number of times each sample. To
Feedback control has been applied to computing systems, usually taking a designed system and closing a loop to adjust some of its parameters. However, the design of computing systems components as controllers have shown advantages with respect to state-of-the-art techniques, especially in the scheduling domain, where uniprocessor schedulers have been designed as discrete-time control structures. H
Delirium is a serious and common condition in the intensive care unit (ICU), which affects 30-50 % of the patients and is associated with increased mortality and morbidity in the context of long-term outcomes. No evidence-based treatment for delirium exists, and currently, delirium is mainly treated pharmacologically with haloperidol, a typical antipsychotic agent. The “Agents Intervening against
In this article, the account-making of social workers and institutional care staff on locked institutional care for youth is analysed, based on empirical material consisting of 10 interviews with 25 members of the two professions. The study departs from a Swedish context where locked institutional care for youth is mainly provided for individuals who are in compulsory care due to criminality, drug
Introduction: Snus is suggested as a risk factor for cardiometabolic disease, but little is known about health effects in young populations, particularly in women. We aimed to investigate associations between snus and cardiometabolic health markers among young men and women. Aims and Methods: This study was conducted within the BAMSE (Swedish acronym for Children, Allergy, Environment, Stockholm,
Purpose: To achieve the high sensitivity of digital breast tomosynthesis (DBT), a time-consuming reading is necessary. However, synthetic mammography (SM) images, equivalent to digital mammography (DM), can be generated from DBT images. SM is faster to read and might be sufficient in many cases. We investigate using artificial intelligence (AI) to stratify examinations into reading of either SM or
Background: Alzheimer’s disease (AD) is an insidiously progressive neurodegenerative disorder that is characterized by multiple cognitive impairments and gradual loss of independence in carrying out activities of daily living (ADL). Currently, the predominant therapy for mild-to-moderate AD is cholinesterase inhibitors (ChEIs), which have been shown to have positive effects on symptoms compared wi
The effect of ultraviolet radiation (UV) (255-325 nm) on stomatal closure was investigated on tef (Eragrostis tef (Zucc) Trotter) in the presence of white light (ca 50 .mu.mol m-2 s-1). The action spectrum showed that UV (ca 2 .mu.mol m-2 s-1, half band width about 10 nm) of 285 nm or shorter wavelengths was very efficient in causing stomatal closure. The effectiveness decreased sharply towards lo
Computer programming should be expressing the complicated in easily understandable parts. General languages provide tools and abstractions that allow many different problems to be formulated and solved. Unfortunately, these abstraction only rarely match the problem area precisely, resulting in solutions that are obscured by the need for support code unrelated to the problem. This can be avoided, b
Despite of intensive search for the proper semiconductor base materials for spintronic devices working at room temperature no appropriate material based on ferromagnetic semiconductors has been found so far. We demonstrate that the phase segregated system with MnSb hexagonal inclusions inside the GaSb matrix, formed directly during the molecular beam epitaxial growth reveals the ferromagnetic prop
Popular Abstract in Swedish Denna avhandling i nationalekonomi består av fyra stycken självständiga akademiska arbeten. Syftet med avhandlingen är att studera vilken roll hälsoförsäkringar spelar för den privata finansieringen av hälso- och sjukvården i låg- och mellaninkomstländer. Arbetena studerar både effektivitets- och fördelningsfrågor med hjälp av olika typer av metoder. De enskilda arbetenThe thesis consists of an introductory chapter and four independent research papers, summarized as follows. The introductory chapter discusses the role of economics in international health and the policy contributions of each of the particular papers. In addition, the data and the methods that have been used are discussed. Paper I, entitled Community-based health insurance in low-income countries:
This book is written by and for researchers who are still in that part of their careers where they are actively using the eye-tracker as a tool; those who have to deal with the technology, the signals, the filters, the algorithms, the experimental design, the programming of stimulus presentation, instructions to participants, working the varying tools for data analysis, and of course, worrying abo
Replications are commonly considered to be important contributions to investigate the generality of empirical studies. By replicating an original study it may be shown that the results are either valid or invalid in another context, outside the specific environment in which the original study was launched. The results of the replicated study show how much confidence we could possibly have in the o
Knowledge about subjects who sustain hip fractures in middle age is poor. This study prospectively investigated risk factors for hip fracture in middle age and compared risk factors for cervical and trochanteric hip fractures. The Malmo Preventive Project consists of 22,444 men, mean age 44 years, and 10,902 women, mean age 50 years at inclusion. Baseline assessment included multiple examinations
OBJECTIVE: To examine possible estrogen dependent endometrial expression of MMP-26 in vitro. DESIGN: Experimental study. SETTING: Department of Obstetrics and Gynecology of the Palacky University Medical School and University Hospital, Olomouc, Czech Republic, Department of Obstetrics and Gynecology, University Hospital, Lund, Sweden. METHODS: We studied MMP-26 mRNA in 14 normal endometrial sample
