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Gene fusion transcripts containing PRDM10 were recently identified in low-grade undifferentiated pleomorphic sarcomas (UPS). Here, we describe the morphologic and clinical features of 9 such tumors from 5 men and 4 women (age: 20 to 61 y). Three cases had previously been diagnosed as UPS, 3 as superficial CD34-positive fibroblastic tumor (SCD34FT), 2 as pleomorphic liposarcoma, and 1 as pleomorphi
Introduction: The 2015 Insulin Injection Technique Questionnaire survey involving 13,289 patients included 898 (6.8%) patients in the pediatric age range (≤ 18 years). Methods: The younger patients included in the questionnaire survey were grouped according to age: Group 1 (G1), 0–6 years, n = 85; Group 2(G2), 7–13, n = 423; Group 3 (G3), 14–18, n = 390. The injection technique was evaluated by me
As part of an extensive air chemistry programme, during summer 1980, on board the Swedish ice-breaker 'Ymer', levels of 222Rn (radon) and its long-lived daughters 210Pb and 210Po were measured. The radon was trapped on charcoal and the long-lived daugther products sampled on filters on a daily basis. In addition, short-lived progenies were followed continuously on the filters in order to achieve a
cDNA encoding rat alpha 1-microglobulin-bikunin was ligated into the transfer vector pVL 1392 and recombined with a wild-type baculovirus. The resulting alpha 1-microglobulin-bikunin-encoding baculovirus was used to infect Trichoplusia ni (Hi-5) insect cells. The infected cells secreted alpha 1-microglobulin with maximal concentrations of 15 mg/liter 5 days after infection. The secreted proteins m
Purpose: The present study was performed as part of an epidemiological study, the Inter99 Eye Study. The aim of the study was to describe refractive errors and visual acuity (VA) in a suburban Danish population.Methods: The Inter99 Eye Study comprised 970 subjects aged 30–60 years and included a random control group as well as groups at high risk for ischaemic heart disease and diabetes mellitus.
Previous models of environmental psychology have put the focus mainly on the cognitive processes, with each step in the process leading to the next in a rather static manner. This may be exemplified by some of the attitude theories developed over the last years (e.g. Ajzen and Fishbein, 1980; Stern, 2000). Among the few exceptions to the cognitive approach is Russell’s Circumplex model of emotiona
Uppsatsen undersöker hur självförvållat rus har beaktats i svensk straffrätts ansvarsbedömning över tid. Analysen fokuserar på hur förhållandet mellan gärningsmannens faktiska sinnestillstånd, uppsåtskravet och möjligheten att utkräva straffansvar har förändrats. Framställningen tar sin utgångspunkt i den svenska stormaktstiden och följer utvecklingen fram till dagens reglering i 1 kap. 2 § 2 st. This thesis examines how self-induced intoxication has been taken into account in Swedish criminal law's assessment of criminal responsibility and intent over time. The analysis focuses on how the relationship between the perpetrator's actual state of mind, the requirement of intent, and the possibility of imposing criminal liability has changed. The presentation takes its starting point i
Uppsatsen behandlar förhållandet mellan plan- och bygglagen (2010:900) och strandskyddsbestämmelserna i miljöbalken (1998:808) vid prövningen av bygglov och förhandsbesked. Fokus ligger på hur strandskyddet påverkar prövningen i plan- och bygglagen och om en sådan påverkan har stöd i lagstiftningen. Frågan aktualiseras mot bakgrund av att plan- och bygglagen innehåller flera hänvisningar till miljThis thesis examines the relationship between the Planning and Building Act (2010:900) and the shore protection rules in the Environmental Code (1998:808) when assessing building permits and advance notice. Mainly focus is on how the shore protection affects assessments under the Planning and Building Act and whether such an impact is supported by legislation. The issue is relevant given that the
Denna uppsats undersöker hur arbetsgivarens omplaceringsrätt är utformad och begränsad i svenskt rätt, samt hur den kan tillämpas vid hybridarbete. Uppsatsen redogör för hur arbetsskyldigheten som följer av avtal, lagstiftning och arbetsrättslig praxis tillsammans sätter ramarna för hur en omplacering får genomföras. De frågeställningar som ligger till grund för uppsatsen avser dels omplaceringsräThis thesis examines how the employer’s right to relocate employees is structured and limited under Swedish law and how this right may be applied in the context of hybrid work. The thesis outlines how the duty to work is based on employment contracts, legislation and case law, which collectively sets the framework within which relocation of employees may take place. The research questions underlyi
Introduction Severe osteogenesis imperfecta (OI) is a debilitating disease with no cure or sufficiently effective treatment. Mesenchymal stem cells (MSCs) have good safety profile, show promising effects and can form bone. The Boost Brittle Bones Before Birth (BOOSTB4) trial evaluates administration of allogeneic expanded human first trimester fetal liver MSCs (BOOST cells) for OI type 3 or severe
Background: Symptomatic osteoarthritis of the basal joint of the thumb (trapeziometacarpal joint) is a common disabling condition mainly affecting women. It is frequently treated with complete removal of the trapezium with or without soft-tissue interposition. There is limited evidence about whether removal of the trapezium affects stability of the wrist joint and increases the risk of developing
This thesis explores the state of regional cooperation, particularly in the field of security, among Denmark, Finland, Iceland, Norway and Sweden (Norden). The author examines correlation between a set of socially constructed factors and the creation of a common Nordic profile in a regional security organization, the OSCE. Formally, Norden is divided in the EU and the non-EU members, but unofficia
This study aims to investigate and disentangle the impact of land use and climate variability on the Baltic Sea coastal zone from a millennial perspective. To assess the environmental status of the coastal zone we make use of siliceous microfossils (mainly diatoms), stable nitrogen and carbon isotopes, organic carbon accumulation rates, and lithological changes analyzed in a sediment core collecte
Denna avhandling syftar till att utöka kunskapsbasen om hur grundskolelärare i Sverige kommunicerar och interagerar i sitt yrke och vilka arbetsrelaterade hälsoproblem de upplever. Avhandlingen bygger på två studier, vilka genererat tre artiklar. Papper I är baserat på resultat från en explorativ studie med fokusgruppsmetodik. I denna studie undersöktes arbetsplatskommunikationspraxis bland skolläDuring recent years, schoolteachers in Sweden have experienced many reforms and societal changes, resulting in altered conditions for work. Subsequently, many teachers have reported an increased workload and reduced well-being. In addition, previous research has identified a need for more contextually anchored measures of demands and resources pertaining to teachers’ work situation.This dissertati
We study thermal equilibrium of classical pointlike counterions confined between symmetrically charged walls at distance d. At very large couplings when the counterion system is in its crystal phase, a harmonic expansion of particle deviations is made around the bilayer positions, with a free lattice parameter determined from a variational approach. For each of the two walls, the harmonic expansio
Visceral arteries such as the coeliac (CA), superior mesenteric (SMA), and the inferior mesenteric artery (IMA) might be affected by atherosclerotic occlusive lesions with or without thrombosis or embolization causing ischaemic symptoms from the gastrointestinal tract.After treatment of an acute event, these patients should be offered both non-pharmacological and pharmacological secondary preventi
Objective To evaluate the outcome of screening for structural malformations in twins and the outcome of screening for twin-twin transfusion syndrome (TTTS) among monochorionic twins through a number of ultrasound scans from 12 weeks' gestation. Methods Enrolled into this prospective multicenter observational study were women with twin pregnancies diagnosed before 14 + 6 gestational weeks. The mono
