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Detection of circulating tumor cells and circulating tumor DNA before and after mammographic breast compression in a cohort of breast cancer patients scheduled for neoadjuvant treatment

PurposeIt is not known if mammographic breast compression of a primary tumor causes shedding of tumor cells into the circulatory system. Little is known about how the detection of circulating biomarkers such as circulating tumor cells (CTCs) or circulating tumor DNA (ctDNA) is affected by breast compression intervention.MethodsCTCs and ctDNA were analyzed in blood samples collected before and afte

The effect of equal versus expanding spacing practice on the deliberate learning of L2 collocations

Research comparing equal and expanding spacing schedules in relation to L2 single words is limited. Moreover, none of the existing studies has examined the learning of formulaic language. The current study aims to address this gap by investigating the impact of equal and expanding intervals on the long-term retention of L2 collocations in deliberate learning contexts. Eighty-three university learn

Irreversible electroporation of hepatocellular carcinoma and colorectal cancer liver metastases : A nationwide multicenter study with short- and long-term follow-up

Introduction: A nationwide multicenter study was performed to examine short- and long-term effects of irreversible electroporation (IRE) for hepatocellular carcinoma (HCC) and colorectal cancer liver metastases (CRCLM). IRE is an alternative method when thermal ablation is contraindicated because of risk for serious thermal complications. Methods: All consecutive patients in Sweden treated with IR

Efficacy and safety of balloon kyphoplasty compared with non-surgical care for vertebral compression fracture (FREE): a randomised controlled trial

Background Balloon kyphoplasty is a minimally invasive procedure for the treatment of painful vertebral fractures, which is intended to reduce pain and improve quality of life. We assessed the efficacy and safety of the procedure. Methods Adults with one to three acute vertebral fractures were eligible for enrolment in this randomised controlled trial at 21 sites in eight countries. We randomly as

Anti-Inhibitor Coagulant Complex Prophylaxis in Hemophilia with Inhibitors

Background Patients with severe hemophilia A and factor VIII inhibitors are at increased risk for serious bleeding complications and progression to end-stage joint disease. Effective strategies to prevent bleeding in such patients have not yet been established. Methods We enrolled patients with hemophilia A who were older than 2 years of age, had high-titer inhibitors, and used concentrates known

Von Willebrand factor/factor VIII concentrate (Haemate(R) P) dosing based on pharmacokinetics: a prospective multicenter trial in elective surgery.

Background: While plasma-derived concentrates containing large amounts of von Willebrand factor (VWF) are effective in treating von Willebrand disease (VWD), optimal dosing remains to be fully characterized. Objectives: To determine the feasibility of dosing Haemate P-(R) VWF/factor VIII (FVIII) concentrate based on pharmacokinetics (PK) in the management of surgical subjects with VWD. Methods: VW

Effects of pH management during selective antegrade cerebral perfusion on cerebral microcirculation and metabolism: alpha-stat versus pH-stat

BACKGROUND: Selective cerebral perfusion (SCP) is used for extending the period during which surgical procedures can be safely performed. We sought to determine the direct effects of pH management on cerebral microcirculation and metabolism during SCP. METHODS: An experimental SCP porcine model was created by selectively allowing cold perfusate only into the bicarotid brachiocephalic trunk during

Rape in the news : On rape genres in Swedish news coverage

ABSTRACT Introduction Methods The lonely pervert rape The sex slavery rape The celebrity rape The suburb rape Conclusion References  Full Article  Figures & data References  Citations Metrics Licensing  PDF ABSTRACT This article deals with narratives of rape in Swedish newspapers between 1990 and 2015. Though perpetuating mThis article deals with narratives of rape in Swedish newspapers between 1990 and 2015. Though perpetuating myths and stereotypes about rape, rapists and rape victims, the main argument is that the narratives of rape in the news are diverse. This diversity is analysed in terms of different genres—narratives of “the lonely pervert”; “the sex slavery rape”; “the celebrity rape”; and “the suburb rape

Parenting and parenting support in Germany and Sweden: Convergence and persistent dissimilarities

Parenting support constitutes a long-established part of both the Swedish and the German portfolio of public social services. It originated in the 1920s in Germany, the 1930s in Sweden. Support measures and underlying philosophies have steadily changed in both countries, thereafter. The 1990s saw a new ‘turn to parenting’ and also new measures in Sweden and Germany. In this article, we ask how par„Parenting“ und „Parenting Support“ in Deutschland und Schweden. Konvergenz und fortdauernde Unterschiede.

The dancing bear from Spain : On the eigtheenth-century Swedish reception of Tomás de Iriarte's Fábulas literarias (1782)

The article depicts the intense and at times unpredictable fable transfer in eighteenth-century Europe by tracing the source text of one of the most acclaimed works in Swedish fable history, Anna Maria Lenngren’s “Björndansen” [The dance of the bear]. This verse fable, published in Stockholms Posten in 1799 and bringing questions of literary quality and literary criticism into focus, was classifieThe article depicts the intense and at times unpredictable fable transfer in eighteenth-century Europe by tracing the source text of one of the most acclaimed works in Swedish fable history, Anna Maria Lenngren’s “Björndansen” [The dance of the bear]. This verse fable, published in Stockholms Posten in 1799 and bringing questions of literary quality and literary criticism into focus, was classifie

Assessing the effect of d-xylose on the sugar signaling pathways of Saccharomyces cerevisiae in strains engineered for xylose transport and assimilation

One of the challenges of establishing an industrially competitive process to ferment lignocellulose to value-added products using Saccharomyces cerevisiae is to get efficient mixed sugar fermentations. Despite successful metabolic engineering strategies, the xylose assimilation rates of recombinant S. cerevisiae remain significantly lower than for the preferred carbon source, glucose. Previously,

Still a poster child for social investment? Changing regulatory dynamics of early childhood education and care in Denmark and Sweden

This paper investigates the regulation of publicly organized early childhood education and care (ECEC) in Denmark and Sweden, through the regulatory welfare state (RWS) framework. The analysis focuses on how alterations in funding and quality of care are shaped by governmental and nongovernmental actors at national and local levels of government. Through focused structured analysis, we examine howThis paper investigates the regulation of publicly organized early childhood education and care (ECEC) in Denmark and Sweden, through the regulatory welfare state (RWS) framework. The analysis focuses on how alterations in funding and quality of care are shaped by governmental and nongovernmental actors at national and local levels of government. Through focused structured analysis, we examine how

Intermittent scanning continuous glucose monitoring is safe and useful in postsurgical glucose monitoring after pancreatoduodenectomy

Aims: Intermittently scanned continuous glucose monitoring (isCGM) systems have not been thoroughly evaluated during in-hospital stay, and there are concerns about accuracy during various conditions. Patients undergoing pancreatoduodenectomy have an increased risk of hyperglycaemia after surgery which is aggravated by parenteral nutrition therapy. This study aims to evaluate glycaemic control and

Long-term Safety of Revascularization Deferral Based on Instantaneous Wave-Free Ratio or Fractional Flow Reserve

Background: Deferral of coronary revascularization is safe whether guided by instantaneous wave-free ratio (iFR) or by fractional flow reserve (FFR). We aimed to assess long-term outcomes in patients deferred from revascularization based on iFR or FFR in a large real-world population. Methods: From 2013 through 2017, 201,933 coronary angiographies were registered in the Swedish Web-System for Enha

The Rule of Law in Economic Emergency in the European Union

Both decades of the 21st century have been categorized as testing the EU constitutional foundations in the course of different crises, that have been challenging the viability of the European integration and causing alterations to EU constitutional design. The rhetoric of crisis/emergency in the EU has been consistently deployed in the areas of public security, environmental protection, migration Both decades of the 21st century have been categorized as testing the EU constitutional foundations in the course of different crises, that have been challenging the viability of the European integration and causing alterations to EU constitutional design. The rhetoric of crisis/emergency in the EU has been consistently deployed in the areas of public security, environmental protection, migration

Attitudes and beliefs regarding umbilical cord clamping among midwives, obstetricians, and neonatologists in Sweden: A national cross-sectional survey

ObjectiveThe study aimed to explore attitudes and beliefs among midwives, obstetricians, and neonatologists regarding umbilical cord clamping practices, including scenarios involving neonatal compromise. The study was conducted in the context of exploring the potential for implementing intact cord resuscitation.Study designA national cross-sectional survey was administered electronically, using anObjectiveThe study aimed to explore attitudes and beliefs among midwives, obstetricians, and neonatologists regarding umbilical cord clamping practices, including scenarios involving neonatal compromise. The study was conducted in the context of exploring the potential for implementing intact cord resuscitation.Study designA national cross-sectional survey was administered electronically, using an

No polarization–Expected Values of Climate Change Impacts among European Forest Professionals and Scientists

The role of values in climate-related decision-making is a prominent theme of climatecommunication research. The present study examines whether forest professionals are more drivenby values than scientists are, and if this results in value polarization. A questionnaire was designedto elicit and assess the values assigned to expected effects of climate change by forest professionalsand scientists w