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https://www.iko.lu.se/evenemang/nordic-baltic-symposium-animal-studies-convene-lund-university - 2026-07-01

In this paper I propose an emancipation effect that may follow from the ‘reducing effect’ of frequency (Bybee 2006): if a reduced realization of an item gains in frequency, it will become conceptually independent from the full form. In a context of grammaticalization, I show that this is the case for the form gonna, which is becoming emancipated from its source form going to. I use corpus data of

Streptococcus pyogenes infects over 700 million people worldwide annually. Immune evasion strategies employed by the bacteria include binding of the complement inhibitors, C4b-binding protein (C4BP) and Factor H in a human-specific manner. We recently showed that human IgG increased C4BP binding to the bacterial surface, which promoted streptococcal immune evasion and increased mortality in mice.

Pyranose 2-oxidase (P20x) has several proposed biotechnological applications such as a bio-component in biofuel cells or for carbohydrate transformations. To improve some of the catalytic properties of P20x from Trametes multicolor, we selected a semi-rational approach of enzyme engineering, saturation mutagenesis of active-site residues and subsequent screening of mutant libraries for improved ac

Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease encompassing a wide range of symptoms that can emanate from pathology in virtually any organ system. Severe SLE includes involvement of the central nervous system and kidneys. One of the hallmarks of the disease is a multitude of autoantibodies, indicating a breakdown in self tolerance. The corresponding antigens have been fou

Presented here is an engineered protein domain, based on Protein A, that displays a calcium-dependent binding to antibodies. This protein, ZCa, is shown to efficiently function as an affinity ligand for mild purification of antibodies through elution with ethylenediaminetetraacetic acid. Antibodies are commonly used tools in the area of biological sciences and as therapeutics, and the most commonl

The prevalence of allergic disease is continuing to increase worldwide, and it has even become a major concern in public health. Allergic reactions are developed to otherwise harmless substances and may be both life-threatening as well as discomforting for patients in their daily life. Therefore, a more detailed knowledge about how antibodies interact with allergens and effector cells in allergic

Every single State has its own rules: legal persons are created based on the domestic laws and States tax them according to their own tax laws. Thus, differences and imperfect legal relationships are inevitable at the international level. The existence of legal entities formed under diverse domestic laws which are not similar to each other leads to disparities and thus, to difficulties to have a c

Information system have become exceedingly important in our daily working lives and by that tightly connected with jobs. Job satisfaction is relatively explored research field which has become very popular in the last decades. But how do information systems affect other aspects of work, and how does our perception of our working life affect our acceptance of information systems is relatively unexp

The C programming language, while offering high performance and low-level control, is memory-unsafe. This makes it prone to programming errors that can result in serious software vulnerabilities and system instability. In this paper, we investigate the feasibility of transitioning a large code base from C to a memory-safe alternative, specifically Rust, in the context of a large company in telecom

Multiple missiles were fired at Erbil on February 15, killing at least one civil contractor and injuring at least one American national. It is likely that the attack was conducted by an Iranian proxy in order to put pressure on President Biden to lift the sanctions against the country and return to the 2015 nuclear deal.

The polyamines putrescine, spermidine, and spermine are organic cations that are required for cell growth and differentiation. Ornithine decarboxylase (ODC), the first and rate-limiting enzyme in the polyamine biosynthetic pathway, catalyzes the conversion of ornithine to putrescine. As the polyamine biosynthetic pathway is essential for the growth and survival of Leishmania donovani, the causativ

We show that the common claim that internal validity should be understood as prior to external validity has, at least, three epistemologically problematic aspects: experimental artefacts, the implications of causal relations, and how the mechanism is measured. Each aspect demonstrates how important external validity is for the internal validity of the experimental result.