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Levodopa-induced dyskinesia (LID) is a debilitating complication of symptomatic therapy in Parkinson's disease. Although there is compelling evidence that striatal pathophysiology is a major driver of LID, the specific circuit mechanisms governing its expression remain obscure. To address this gap, molecular, cellular, and behavioral strategies were used to interrogate circuits in a mouse model of

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As I write this, there are numerous horrible wars and acts of terror taking place all over the world. However, it is my belief that the situation would be even worse without diplomats working as mediators, and for them to be able to fulfil their duties they need to be inviolable. Through the Vienna Convention on Diplomatic Relations of 1961, which is believed to reflect customary international law

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Digitaliseringen har ändrat samhället på många sätt. Idag delar människor med sig av all sorts information om sig själva och andra under nästan alla timmar på dygnet. Människor har anpassat sig till ett samhälle där de känner sig manade att hela tiden vara uppkopplade och representerade på internet. På senare tid har dock människor börjat inse att spridandet av information på internet kan ge oanadDigitalization has changed society in many ways. One of the results of the development of the online world is that people have formed the habit of sharing all sorts of information about themselves and others to everyone around them at all times. People have adapted to a society where they feel a compulsion to be repeatedly connected and represented on digital networks. However, individuals have st

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For years researchers have studied retention and turnover, yet there is still no single solution for the problem of balancing both these concepts in organizations. Turnover is defined as the rupture of ties between an employee and his/her organization, whilst retention is defined as the option of the employee to stay in the organization while not looking out for other job alternatives. These two c

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Today, we live in an age that is continually witnessing tension, strife and terrorism as a direct product of unequal distribution of wealth and opportunities for a good life. In Uganda for over two and half decades, war, insurgency and deprivation have been the realities of the people living in Northern Uganda. This evidently has lead to an imbalance in the Ugandan society with the North standing

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Denna uppsats undersöker de levda erfarenheterna hos japanska migranter i Sverige, en grupp som omfattar cirka 4 600 individer, varav nästan 80 procent har valt att permanent bosätta sig i Sverige. De återstående 20 procenten är tillfälliga invånare, som studenter, forskare eller utstationerade chefer, verksamma i något av de cirka 200 japanskägda företagen i landet. Till skillnad från andra europThis thesis explores the lived experiences of Japanese migrants to Sweden, a demographic that includes approximately 4,600 individuals, of whom nearly 80 percent chose to settle permanently in Sweden. The remaining 20 percent are temporary residents, as students, researchers, or as expatriate managers, working in one of the roughly 200 Japanese-owned companies in the country. In contrast to other

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BackgroundCrop yields are lowest in sub-Saharan Africa compared to other regions, and this is true even for such an important staple crop as maize. Persistence of patches of low crop vigour side-by-side to patches with healthier maize crops has been shown to significantly contribute to low yields on smallholdings. Farmers' perspectives on the presence of such poor patches are important as far as t

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To develop sustainable supply chains in a way that their negative environmental and social effects are minimized, shortand long-term targets should be set. The transformation of supply chains towards these targets calls for the development of innovative strategies and the need to continuously identify, classify, and tackle the challenges that can hinder the execution of such strategies. To develop

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The gene for an IgA-binding protein from a group A streptococcal strain was cloned and expressed in Escherichia coli. The IgA-binding protein, called protein Arp, was purified on IgA-Sepharose, allowing complete purification in a single step. Analysis of protein Arp by Western immunoblotting demonstrated a major IgA-binding band, with an apparent molecular weight of 42 kD. The purified protein was

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The aim of the project was to examine interactions between motor vehicle drivers and cyclists at intersections and the impact of infrastructure design and motor vehicle characteristics on interactive behaviour. The project activities included literature reviews on cycling infrastructure at intersections, vehicle driver behaviour and cyclist behaviour; questionnaires among motor vehicle drivers andThe aim of the project was to examine interactions between motor vehicle drivers and cyclists at intersections and the impact of infrastructure design and motor vehicle characteristics on interactive behaviour. The project activities included literature reviews on cycling infrastructure at intersections, vehicle driver behaviour and cyclist behaviour; questionnaires among motor vehicle drivers and

Parrondo’s Paradox and Epistemology – combining two faulty strategies to get good results

Parrondo’s Paradox and Epistemology – combining two faulty strategies to get good results PARRONDO’S PARADOX AND EPISTEMOLOGY – WHEN BAD THINGS HAPPEN TO GOOD COGNIZERS (AND CONVERSELY) Fredrik Stjernberg Philosophy, Linköping University frest@irk.liu.se ABSTRACT: According to Parrondo’s Paradox, there will be cases where a subject facing two probabilistically losing strategies has a probabilistic

https://www.fil.lu.se/hommageawlodek/site/papper/StjernbergFredrik.pdf - 2026-07-12

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The growing incidence and prevalence of sexually transmitted infections among young people, particularly HIV, is a public health concern in Uganda. There is increasing evidence that Ugandan youth engage in risky sexual behaviors, transactional sex, and experience sexual coercion. Most research on sexual behaviors has been limited to inter- and intra-personal factors that influence sexual behaviors

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This thesis provides an in-depth exploration of how the EU’s resilience-building initiatives for the Eastern Neighbourhood have evolved against Russian hybrid threats since 2022. Russian invasion of Ukraine significantly altered the security order on the continent, reshaping the EU’s perception of its own security. In response to increased hybrid threats, the EU has employed extraordinary regulato

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This essay examines the personifications of Death in Markus Zusak’s The Book Thief (2005), Christopher Moore’s A Dirty Job (2006) and George Pendle’s Death: A Life (2008). The personifications are analysed in terms of gender, anthropomorphism, (im)mortality, agency in conceptual death and attitude towards their occupation as Death. The personifications are also compared to previous portrayals in r

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“Water is life”. During the past decade this phrase has been used repeatedly to emphasize the importance of a number of issues surrounding water services provision including, supply, distribution, governance and political will. This research seeks to investigate the Nairobi City Water and Sewerage Company (NCWSC), a water utility in Kenya, which faces the monumental task of providing water and san

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BACKGROUND: After amputation, the sensorimotor cortex reorganizes, and these alterations might influence motor functions of the remaining extremities.OBJECTIVE: The authors examined how amputation of the dominant or nondominant upper or lower extremity alters deftness in the intact limbs.METHODS: The participants were 32 unilateral upper- or lower-extremity amputees and 6 controls. Upper-extremity