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Science and proven experience : a Swedish variety of evidence based medicine and a way to better risk analysis?

A key question for evidence-based medicine (EBM) is how best to model theway in which EBM should ‘[integrate] individual clinical expertise and the bestexternal evidence’. We argue that the formulations and models available inthe literature today are modest variations on a common theme and face verysimilar problems when it comes to risk analysis, which is here understoodas a decision procedure comA key question for evidence-based medicine (EBM) is how best to model the way in which EBM should‘[integrate] individual clinical expertise and the best external evidence’. We argue that the formulations and models available in the literature today are modest variations on a common theme and face very similar problems when it comes to risk analysis, which is here understood as a decision procedure

A combined strategy of feature selection and machine learning to identify predictors of prediabetes.

Objective: To identify predictors of prediabetes using feature selection and machine learning on a nationally representative sample of the US population. Materials and methods: We analyzed n = 6346 men and women enrolled in the National Health and Nutrition Examination Survey 2013-2014. Prediabetes was defined using American Diabetes Association guidelines. The sample was randomly partitioned to Objective: To identify predictors of prediabetes using feature selection and machine learning on a nationally representative sample of the US population. Materials and methods: We analyzed n = 6346 men and women enrolled in the National Health and Nutrition Examination Survey 2013-2014. Prediabetes was defined using American Diabetes Association guidelines. The sample was randomly partitioned to t

New constraints on paleoreconstructions through geochronology of mafic dyke swarms in North Atlantic Craton

Ett antal superkontinenter har existerat under jordens 4.6 Ga ( miljarder år gamla ) historia. Utav dessa är superkontinenten Pangea, som betyder ”allt land”, den senaste och mest väldefinierade. Bildning och uppsprickning av superkontinenter drivs av plattektoniska processer som i sin tur beror på strömningar ( konvektion ) i jordens mantel. Förutom dessa processer så anses numera mantelplymer haEarth history is punctuated by a series of events of supercontinent amalgamation and break-up. Fragments of old continents display rifted margins and orogenic sutures that testify their involvement in supercontinent cycles. Periods of break-up are associated with widespread magmatism due to extensional thinning and rifting of the lithosphere and in some instances the arrival of mantle plumes. Mant

Gestational Islet Autoimmunity, Infections, and Type 1 Diabetes

Popular Abstract in Swedish Förekomsten av typ 1 (insulinberoende) diabetes före 15 års ålder har ökat under de senaste åren (Fig. 1) och barnen är allt yngre vid insjuknandet. Sjukdomen anses vara autoimmun, vilket innebär att kroppens eget immunförsvar angriper de insulinproducerande ?-cellerna i bukspottkörteln. En ärftlig benägenhet, som fr.a. är kopplad till s.k. vävnadsantigen på cellerna, mThe intention of this thesis was to investigate autoimmune markers for type 1 diabetes, together with signs of enterovirus infections during the pre- and perinatal period of life, and their possible association with the development of diabetes during childhood, adolescence, and young adulthood. We found that: 1. Newborns with ABO immunization, linked in epidemiological studies with heightened diab

Importance of renal function in cardiac surgery

Popular Abstract in Swedish Njurfunktion inom hjärtkirurgi Akut njursvikt (AKI) efter hjärtkirurgi är en allvarlig komplikation som förekommer i 25-35 % av alla patientfall. AKI medför förhöjd risk för allvarliga komplikationer och död efter hjärtkirurgi. Ett stort fokus ligger på detektion, prevention och behandling av AKI och forskningsfältet uppdateras kontinuerligt. En rad olika läkemedel har Abstract Acute kidney injury (AKI) is a common and serious complication after cardiothoracic surgery and is associated with increased short- and long-term mortality risk. Despite extensive studies in the field, a comprehensive understanding of this syndrome has remained elusive, partly due to divergent definitions of AKI and partly due to the limitations of available routine biomarkers to predict,

En studie av konkurrensklausuler i företagsförvärvsavtal

Att företag köper upp andra företag är en viktig del av näringslivet. Det är ett sätt för företag att snabbt växa och tillskansa sig värden som gör företaget starkare. En företagsöverlåtelse är dock inte riskfri. Den är ofta kostsam och det finns inga garantier för att köpet lönar sig. Det köpande företaget kan dock till viss del skydda sin investering genom att i överlåtelseavtalet föra in en konCorporate acquisitions are a vital part of the business world. They are a way to ensure growth. They are also a good way of adding values to the company, which in turn makes the company stronger. However, an acquisition is not risk free. It is often expensive and there are no guarantees that the acquisition will be profitable in the end. The buyer can to some extent protect its investment with a n

”Alltså, klienter är ju arga och kan säga saker som de inte menar” En kvalitativ studie om socialsekreterares uttalanden kring hot på sin arbetsplats

Abstract Authors: Filippa Daugbjerg & Kerstin Månsson Title: “So, clients are angry and say things they do not mean” – A qualitative study of the social worker’s statements about threats in the workplace Supervisor: Karin Kullberg The aim of this study was to examine what social workers in social services, working with economical support found as risk factors when a threatful situation arises

Improved analysis of MRI tractography data: Group comparisons of parameters along fibre tracks

Diffusion MRI is an imaging technique capable of inferring information about the tissue microstructure, based on magnetic resonance imaging (MRI). Diffusion MRI data can be analysed using tractography, a tool able to represent the structure of the white matter (WM) in the brain. Tractography is commonly used qualitatively, but in this report, an algorithm for quantitative tractography was develope

Den officiella, formella & informella organisationsbilden - Malmö Förskoleförvaltning

Title: The Official, Formal & Informal organizational image – The Pre-School Administration in Malmo City Date: 2015-02-18 Course: FEKH49, Degree Project Undergraduate level, Business Administration, Undergraduate level, 15 University Credits Points (UPC) or ECTS‐cr) Authors: Surra Al Sakban, Emil Gustafsson, Karin Runnerström Advisor: Louise Bringselius Key words: Public sector, Professional

Do parents counter-balance the carbon emissions of their children?

It is well understood that adding to the population increases CO2 emissions. At the same time, having children is a transformative experience, such that it might profoundly change adult (i.e., parents’) preferences and consumption. How it might change is, however, unknown. Depending on if becoming a parent makes a person “greener” or “browner,” parents may either balance or exacerbate the added COIt is well understood that adding to the population increases CO2 emissions. At the same time, having children is a transformative experience, such that it might profoundly change adult (i.e., parents') preferences and consumption. How it might change is, however, unknown. Depending on if becoming a parent makes a person "greener" or "browner," parents may either balance or exacerbate the added CO

Widespread White Matter Abnormalities in Concussed Athletes Detected by 7T Diffusion Magnetic Resonance Imaging

Sports-related concussions may cause white matter injuries and persistent post-concussive symptoms (PPCS). We hypothesized that athletes with PPCS would have neurocognitive impairments and white matter abnormalities that could be revealed by advanced neuroimaging using ultra-high field strength diffusion tensor (DTI) and diffusion kurtosis (DKI) imaging metrics and cerebrospinal fluid (CSF) biomarSports-related concussions may cause white matter injuries and persistent post-concussive symptoms (PPCS). We hypothesized that athletes with PPCS would have neurocognitive impairments and white matter abnormalities that could be revealed by advanced neuroimaging using ultra-high field strength diffusion tensor (DTI) and diffusion kurtosis (DKI) imaging metrics and cerebrospinal fluid (CSF) biomar

Prognostic Models for Mortality and Morbidity in Heart Failure with Preserved Ejection Fraction

Importance: Accurate risk prediction of morbidity and mortality in patients with heart failure with preserved ejection fraction (HFpEF) may help clinicians risk stratify and inform care decisions. Objective: To develop and validate a novel prediction model for clinical outcomes in patients with HFpEF using routinely collected variables and to compare it with a biomarker-driven approach. Design, Se

Sleep and insomnia symptoms in adolescence

Vi spenderar en tredjedel av våra liv sovandes och sömn är en avgörande faktor för god hälsa och välbefinnande. Men det är även viktigt att erkänna sömnens komplexitet, eftersom det är flera faktorer som kan påverka sömnen. Både biologiska, kontextuella och psykosociala faktorer har inverkan på ungdomarnas sömn. Otillräcklig sömn, sömnproblem och symptom på insomni är vanligt hos ungdomar. SömnlösInsufficient sleep, sleep problems and insomnia are common in adolescents, and insomnia and insufficient sleep are public health concerns that can impact adolescents’ mental and physical health. There are several different treatments for sleep problems and insomnia, and there is a great focus on the problem when it has already arisen. However, since this is a public health problem, it is important

Methodology for developing reduced reaction mechanisms, and their use in combustion simulations

Combustion, present in a vast majority of energy and material production as well as in transportation, represents a foundation of our modern society. To improve and optimize the applications relying on combustion demand a high level of knowledge, and an ability to simulate the combustion process. To do so three-dimensional Computational Fluid Dynamic (CFD) combustion simulations can be used, whereCombustion, present in a vast majority of energy and material production as well as in transportation, represents a foundation of our modern society. To improve and optimize the applications relying on combustion demand a high level of knowledge, and an ability to simulate the combustion process. To do so three-dimensional Computational Fluid Dynamic (CFD) combustion simulations can be used, where

Sveriges lokala och regionala kollektivtrafik - en analys av trender, utmaningar och utvecklingsmöjligheter

Kollektivtrafiken skapar nytta för både privatpersoner och samhället i stort, och bidrar med bemötandet av en rad samhällsmål relaterade till miljö, transportsäkerhet och tillgängliga transportlösningar. För att tillåta fortsatt utveckling av en konkurrenskraftig kollektivtrafik i Sverige, kartläggs och analyseras trender, utmaningar och utvecklingsmöjligheter. Kollektivtrafiken utmanas av bland Public transportation systems provide accessible transport options for all citizens, reducing environmental impact by lowering emissions, improving traffic safety, and promoting social equity and public health. It plays a crucial role in achieving national goals related to sustainable development and climate change mitigation. However, in its aim to increase competitiveness to other modes of trans

Identification and Expression of Oat Hemoglobin

Möjlig lösning av bristen på bloddonationer med hjälp av outforskat havrehemoglobin. Hemoglobin är främst förknippat med blod i oss människor och andra djur, men tänk om någon berättade att det syretransporterade proteinet också finns i växter. Underligt, eller hur? Växter har ju inget blod men ändå finns det där. I denna rapport beskrivs identifieringen av tre nyfunna havrehemoglobin som har likHemoglobin is mainly viewed as an oxygen and carbon dioxide carrier in the blood of animals and thus essential for life as we know it. During the course of evolution, plants have also developed versions of this protein, for similar and different purposes, such as regulation of nitric oxide levels. A lot of research has been put into characterization of hemoglobin from monocots, including rice, bar

What is required by software platforms in order to give a good developer experience?

Vi lever idag i ett digitalt samhälle. Du använder förmodligen själv dagligen olika program och även om all mjukvara i slutändan består av ettor och nollor finns det allt som oftast en person bakom varje program som tagit fram den, en utvecklare. Programmerare tar ofta hjälp från så kallade mjukvaruplattformar. Dessa riktar sig inte direkt mot vanliga användare, utan mot just utvecklare av mjukvaThis research report was carried out in collaboration with Qlik AB and aimed to identify what aspects are needed from a software platform in order for developers to want to use them. It also aimed to identify how well the software platform Qlik Core had implemented these aspects. The research used online questionnaires, interviews and data analysis using Qlik Sense. The research compared how diffe

Performance measuring in nursing homes

Abstract Title: Performance measuring in nursing homes Seminar date: 2021-01-15 Course: FEKH69, Degree Project Undergraduate level, Business Administration, Undergraduate level, 15 University Credits Points (UPC) or ECTS‐ cr) Authors: Filip Danielsson, Woosang Kwon, Christoffer Wikner Advisor/s: Johan Dergård Keywords: Performance measurement, non-financial performance measures, performance eva

New Concept Development of a Blood Glucose-Balancing Functional Beverage

Type 2 Diabetes Mellitus (T2DM) have known to be one of the most common degenerative diseases which highly correlate with lifestyle, including consumption habits. It cannot be denied that the availability and accessibility to high processed food, high in carbohydrates play an important role on increasing the risk of T2DM. On the contrary, consumers’ awareness towards health and nutrition are also

IFRS 3 - Ett fortsatt problem

Title: IFRS 3 – a continuous problem. A study of the standard's development Seminar date: June 1 2012 Course: FEKH95, Degree Project Undergraduate level, Business Administration, Undergraduate level, 15 University Credits Points (UPC) or ECTS-cr Authors: Henric Hammarbro, Anders Jeppsson, Gustav Rybrink Advisor: Erling Green Key words: IFRS 3, goodwill, business combinations, subjectivity, mat