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Tumour-infiltrating lymphocytes as a prognostic and tamoxifen predictive marker in premenopausal breast cancer : data from a randomised trial with long-term follow-up

Background: Tumour-infiltrating lymphocytes (TILs) are of important prognostic and predictive value in human epidermal growth factor receptor 2-positive (HER2+) breast cancer (BC) and triple-negative breast cancer (TNBC), but their clinical relevance in oestrogen receptor-positive/HER2-negative (ER+/HER2−) remains unknown. The primary study aim was to analyse the prognostic effect of TILs on the B

Optical Imaging for Nanowire Mechanics

In this work, we present a stroboscopic detection technique for the study of oscillating nanoscale objects. This optical read-out gives a position accuracy better than 1 nm which is a fraction of both the diffraction limit and the pixel size. The advantage of this stroboscopic method compared to conventional time-averaging techniques, is the time-resolution it provides as well as being non-invasiv

Bone Scan Index and Progression-free Survival Data for Progressive Metastatic Castration-resistant Prostate Cancer Patients Who Received ODM-201 in the ARADES Multicentre Study

Background ODM-201, a new-generation androgen receptor inhibitor, has shown clinical efficacy in prostate cancer (PCa). Quantitative methods are needed to accurately assess changes in bone as a measurement of treatment response. The Bone Scan Index (BSI) reflects the percentage of skeletal mass a given tumour affects. Objective To evaluate the predictive value of the BSI in metastatic castration-r

Microsoft Word - HIS B14 eng

Microsoft Word - HIS B14 eng 1. Course Details 1. Course code HIS B14 2. Course title History: International Contemporary History 3. Cycle (1st, 2nd or 3rd) and code for the depth of study relative to the degree requirements 1st [Undergraduate] G1N 4. Higher education credits 15 5. Details of approval of course Syllabus approved by the Syllabus Committee of the Faculty of the Humanities and Theolo

https://www.historiska.lu.se/media/utbildning/dokument/kursplaner/HISB14_eng.pdf - 2026-06-05

Human Rights in Malaysia

Human Rights in Malaysia Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Methods Focus Areas Business and Human Rights International Humanitari

https://rwi.lu.se/2015/09/29/when-you-do-something-good-you-dont-have-to-get-permission-from-anyone/ - 2026-06-05

Håkan Hydén

Professor emeritus Kontaktinformation E-post: hakan [dot] hyden [at] soclaw [dot] lu [dot] se Mobil: +46 70 530 64 30Organisation Rättssociologiska institutionen Hämtställe: 31 WebbplatsHåkan Hydéns profil i Lunds universitets forskningsportalAndra roller Forskare Affärsrättsligt centrum vid Lunds Universitet, ACLUChefredaktör för Frontiers in Sociology of Law ForskningsområdenRättssociologi som N

https://www.soclaw.lu.se/hakan-hyden - 2026-06-04

The Compatibility of Limitation on Benefits Provisions in Tax Treaties with EC Law

Most bilateral tax treaties contain provisions with the objective of preventing different types of treaty abuse. Limitation on benefits clauses are an example of such provisions, and are generally found in United States tax treaties. These include various tests, which need to be fulfilled by a taxpayer wishing to enjoy the benefits of a tax treaty. Most of the United States tax treaties with EU Me

Component Impact Testing

This master thesis has been made on behalf of Sony Ericsson in co-operation with Machine Design at Lund Institute of Technology. The background is a need within Sony Ericsson to test moulded plastic parts before they are assembled together to a phone. There are today various specified tests that are made on every single phone before it is launched, but they are all made on complete assembled phone

Rådgivares ansvar enligt lag (2003:862) om finansiell rådgivning till konsumenter

I dagsläget äger nästan alla vuxna svenskar finansiella instrument. Det är vidare allmänt känt att sparande i finansiella instrument inte är helt riskfritt. För många individer är besparingarna väldigt viktiga, samtidigt som många saknar den kunskap som krävs för att investera i finansiella instrument. Behovet av finansiell rådgivning har därför ökat kraftigt, varför det får anses oroväckande att

Super adiabatic combustion of carbon-free and carbon-containing fuels

The present work provides a new perspective on super adiabatic combustion (SAC) of fuel/air mixtures involving methane, ethane, propane, butane, heptane, iso-octane, 1-hexene, toluene, ammonia, and hydrogen. The simulations cover the temperature range of 1200–2000 K, initial pressures of 1–50 atm, and equivalence ratios of 0.5–2.0. The detailed chemical kinetic mechanism C3MechV3.5 has been used f

Sustaining Social Interaction in Public Squares After Dark : A socio-physical perspective on the lighting-behaviour relationship

Public squares are everyday life-spaces, essential for supporting social interaction and thereby contributing to individuals’ wellbeing and quality of life. The provision of safe, accessible, and inclusive public squares is an imperative for sustainable urban development of cities and communities.After dark, electric lighting is necessary for sustaining activities, including social interaction, inPublic squares are everyday life-spaces, essential for supporting social interaction and thereby contributing to individuals’ wellbeing and quality of life. The provision of safe, accessible, and inclusive public squares is an imperative for sustainable urban development of cities and communities.After dark, electric lighting is necessary for sustaining activities, including social interaction, in

Risk of estrogen receptor-specific breast cancer by family history of estrogen receptor subtypes and other cancers

BACKGROUND: The extent to which the risk of estrogen receptor (ER)-specific breast cancer is associated with ER status of breast cancer and other cancers among first-degree relatives is unclear.METHODS: This population-based cohort included 464 707 cancer-free women in Stockholm, Sweden, during 1978-2019. For ER-negative and ER-positive breast cancers, we estimated hazard ratios (HRs) associated w

Prognostic impact of circulating tumor cell apoptosis and clusters in serial blood samples from patients with metastatic breast cancer in a prospective observational cohort

Background: Presence of circulating tumor cells (CTCs) is a validated prognostic marker in metastatic breast cancer. Additional prognostic information may be obtained by morphologic characterization of CTCs. We explored whether apoptotic CTCs, CTC clusters and leukocytes attached to CTCs are associated with breast cancer subtype and prognosis at base-line (BL) and in follow-up (FU) blood samples i

Neural correlates of episodic memory buildup in naturalistic viewing behavior

In everyday life, we bind visual samples of the world into a coherent episodic memory via eye movements. Previous eye tracking research revealed that visual scrutiny, gaze transitions between event elements, and refixations during encoding predict successful memory formation. However, little is known about the neural mechanisms of these processes. Here, we combine EEG and eye tracking to investiga

Impaired validity of the new FIGO and Swedish CTG classification templates to identify fetal acidosis in the first stage of labor

Introduction: Cardiotocography (CTG) is the main method of intrapartum fetal surveillance. In 2015 a new guideline was introduced by the International Federation of Gynecology and Obstetrics (FIGO), FIGO-15. In Sweden it was adjusted to SWE-17, replacing the previous national template, SWE-09. This study, conducted at one university hospital and one regional hospital in southern Sweden, evaluated

Svensk forskning i musik – de senaste 100 åren

This article aims to offer an overview of the rise, growth and diversification of academic music research in Sweden. ‘Research in music’ is suggested as a comprehensive term, covering all kinds of research relating to music.In 1915 the Swedish University Chancellor’s office established a syllabus for ‘music history and theory’ at Lund University. The syllabus was initiated by Tobias Norlind, and i

Low-Bias RNA Sequencing of the HIV-2 Genome from Blood Plasma

Accurate determination of the genetic diversity present in the HIV quasispecies is critical for the development of a preventative vaccine: in particular, little is known about viral genetic diversity for the second type of HIV, HIV-2. A better understanding of HIV-2 biology is relevant to the HIV vaccine field because a substantial proportion of infected people experience long-term viral control,

Very short sleep duration reveals a proteomic fingerprint that is selectively associated with incident diabetes mellitus but not with incident coronary heart disease : a cohort study

Background: The molecular pathways linking short and long sleep duration with incident diabetes mellitus (iDM) and incident coronary heart disease (iCHD) are not known. We aimed to identify circulating protein patterns associated with sleep duration and test their impact on incident cardiometabolic disease. Methods: We assessed sleep duration and measured 78 plasma proteins among 3336 participants

Targeted spatial proteomic analysis of CD8+ T- and myeloid cells in tonsillar cancer

Background: Tonsillar cancer is caused by high-risk human papillomavirus (HPV), tobacco smoking, and alcohol abuse. Aspects of the patient’s immune response to this disease have arisen as prognostic factors and treatment targets, reflecting differences in the type and protein expression profile of immune cells. Because tonsillar cancers are heterogenous lesions such data need to be spatially resol

Targeted Investigational Treatment Analysis of Novel Anti-androgen (TITAN) study : ultralow prostate-specific antigen decline with apalutamide plus androgen-deprivation therapy

Objective: To assess the association between achievement of prostate-specific antigen (PSA) levels ≤0.2 ng/mL (henceforth ‘ultralow’) and clinical outcomes in patients in the ‘Targeted Investigational Treatment Analysis of Novel Anti-androgen’ (TITAN) study (ClinicalTrials.gov Identifier NCT02489318) with metastatic castration-sensitive prostate cancer (mCSPC). Patients and Methods: Patients in th