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Relief of Chronic or Resistant Depression (Re-ChORD): A pragmatic, randomized, open-treatment trial of an integrative program intervention for chronic depression

Background: Chronic depression is a particularly disabling mood disorder and treatment outcomes are poor with either psychotherapy or pharmacotherapy alone. There is growing evidence that an integrative treatment approach may be optimal. A novel multi-modal, multi-disciplinary treatment program, Re-ChORD, was developed at the University of British Columbia and evaluated in this pilot study. Method

Early life low-level cadmium exposure is positively associated with increased oxidative stress

Environmental exposure to cadmium (Cd) is known to induce oxidative stress, a state of imbalance between the production of reactive oxygen species (ROS) and the ability to detoxify them, in adults. However, data are lacking on potential effects in early-life. We evaluated urinary concentrations of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG), a recognized marker of oxidative DNA damage, in relati

Land-use change in the Caucasus during and after the Nagorno-Karabakh conflict

Socioeconomic shocks can shape future land-use trajectories. Armed conflicts are an extreme form of a socioeconomic shock, but our understanding of how armed conflicts affect land-use change is limited. Our goal was to assess land-use changes related to the 1991–1994 Nagorno-Karabakh conflict between Armenia and Azerbaijan in the Caucasus region. We classified multi-temporal Landsat imagery, mappe

Effects of dehydroepiandrosterone supplement on health-related quality of life in glucocorticoid treated female patients with systemic lupus erythematosus

The objective of this study was to evaluate the efficacy of low dose dehydroepiandrosterone (DHEA) on health-related quality of life (HRQOL) in glucocorticoid treated female patients with systemic lupus erythematosus (SLE). Forty one women (>= 5 mg prednisolone/day) were included in a double-blind, randomized, placebo-controlled study for 6 months where DHEA was given at 30 mg/20 mg (<= 45/>= 46 y

Skuld och oskuld : barnamord och barnkvävning i rättslig diskurs och praxis omkring 1680–1800

Syftet med denna avhandling är att analysera hur berättelser om skyldiga och oskyldiga mödrar konstruerades under perioden ca. 1680-1800. De två brottskategorierna barnamord och barnkvävning har undersökts. Källmaterialet har huvudsakligen bestått av protokoll från hovrätten, underrätter och sockenstämmor. Jag har klarlagt vilka omständigheter som utreddes vid brottsutredningarna och fick betydelsThe objective of this thesis is to analyse how judicial texts concerning guilty and innocent mothers were constructed during the period of c. 1680-1800. The two crimes of infanticide and overlaying have been examined. Source materials have primarily consisted of proceedings from the appeals court, courts of first instance, and parish meetings. The aim has been to survey the judicial discourse, tha

Vacuum-assisted wound closure and mesh-mediated fascial traction - A novel technique for late closure of the open abdomen

Background Open abdomen (OA) treatment often results in difficulties in closing the abdomen. Highest closure rates are seen with the vacuum-assisted wound closure (VAWC) technique. However, we have experienced occasional failures with this technique in cases with severe visceral swelling needing longer treatment periods with open abdomen. Feasibility and short-term outcome of a novel combination o

Med främmande bagage : Tankar och erfarenheter hos unga människor med ursprung i en annan kultur eller Det postmoderna främlingskapet

Popular Abstract in Swedish Allt fler ungdomar i vårt land, liksom i många andra länder, lever i vardagen med mer än en kultur. En femtedel av eleverna i den svenska skolan är antingen själva födda i ett annat land eller har minst en förälder med utländsk bakgrund. För många av dessa barn och ungdomar har därför inte samhällets dominerande kultur funnits med från början av deras liv. Bekantskapen The present study is based on interviews with 22 youth and young adults. The perspective is phenomenological, since my aim has been to analyse and describe the everyday world as it presents itself to these young people. A process begins in the encounter with the majority culture and the emphasis is on how they think about events and experiences along the road to a more complex life-world. The proc

Synthesis, characterisation and natural abundance Os-187 NMR spectroscopy of hydride bridged triosmium clusters with chiral diphosphine ligands

Treatment of [Os-3(mu-H)(2)(CO)(10)] with the chiral diphosphines BINAP, tolBINAP [(R)-2,2'-bis(di-4-tolylphosphino)-1,1'-binaphthyl], DIOP [(4R,5R)-(-)-O-isopropenylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino) butane] affords [Os-3(mu-H)(2)(CO)(8)(mu-L)] (L = BINAP (1), tolBINAP (2), DIOP (4)) in high yield. The X-ray structures for 1, 2 and 4 are reported, and structural and spectroscopic comp

Land use and occurrence of Andrena hattorfiana and other threatened wild bees (Hymenoptera, Apoidea) at Stenbrohult, Linnaeus' birth place.

During the last decades a striking decline has been observed for wild bees throughout central and north-western Europe, including Sweden. in an area of 64 km' in the parish of Stenbrohult, southern Smaland Andrena hattorfiana, Andrena humilis, Nomada armata and Panurgus hanksianus were studied (in Sweden red-listed as VU, EN, EN and VU). We present occurrence patterns in relation to habitat types

Degranulation patterns of eosinophil granulocytes as determinants of eosinophil driven disease

BACKGROUND: Degranulation of eosinophils in target tissues is considered a key pathogenic event in major chronic eosinophilic diseases. However, because of a lack of appropriate methods, little is known about degranulation of eosinophils in common eosinophilic diseases. METHODS: Using transmission electron microscopic (TEM) analysis, a novel approach has been devised and validated to quantify eosi

Hypervolemia in cerebral vasospasm

Object. Arterial vasospasm is the most common cause of delayed ischemic neurological deficits (DINDs) and one of the major causes of disability following subarachnoid hemorrhage (SAH). Current management of vasospasm involves intravascular volume expansion and hemodynamic augmentation with the goal of increasing cerebral blood flow (CBF). The purpose of this study was to examine the effects of vol

Higher Education for Girls in North American College Fiction 1886-1912

Twenty years after Vassar College welcomed the first American female undergraduates in 1865, the experiences of women college students began to be fictionalized in so-called college stories. This thesis shows how higher education is presented in the novels, collections of short stories, and serialized stories for female readers published before the United States was involved in the First World Wa

Phase behavior of an ionic surfactant with mixed monovalent/polymeric counterions

A "complex salt" of cetyltrimethylammonium (CTA(+)) with short (30 repeating units) polyacrylate (PA(-)) counterions has been synthesized. The phase diagrams of its aqueous mixtures with either the surfactant cetyltrimethylammonium acetate (CTAAc), or the polyelectrolyte NaPA, have been studied by visual inspection through crossed polarizers and by small-angle X-ray scattering. Both of the ternary

Bioelectrocatalytic properties of lignin peroxidase from Phanerochaete chrysosporium in reactions with phenols, catechols and lignin-model compounds

Bioelectrocatalytic reduction of H2O2 catalysed by lignin peroxidase from Phanerochaete chrysosporium (LiP) was studied with LiP-modified graphite electrodes to elucidate the ability of UP to electro-enzymatically oxidise phenols, catechols, as well as veratryl alcohol (VA) and some other high-redox-potential lignin model compounds (LMC). Flow-through amperometric experiments performed at +0.1 V v

Estimation of diurnal air temperature using MSG SEVIRI data in West Africa

Spatially distributed air temperature data with high temporal resolution are desired for several modeling applications. By exploiting the thermal split window channels in combination with the red and near infrared channels of the geostationary MSG SEVIRI sensor, multiple daily air temperature estimates can be achieved using the contextual temperature-vegetation index method. Air temperature was es

The origin and chemical evolution of iron-peak and neutron-capture elements in the Milky Way disk

Popular Abstract in Swedish I Big Bang skapades 3 grundämnen: H, He, och spår av Li. Alla andra grundämnen har bildats i stjärnor. Lågmassiva stjärnor som vår sol kan genom kärnreaktioner skapa grundämnen upp till och med syre i det periodiska systemet, medan mer massiva stjärnor kan skapa grundämnen ända upp till järn. Tyngre grundämnen än järn produceras in slutstadierna av stjärnornas liv, tillAll the elements heavier than Li are created during stellar evolution. Even if our knowledge of this process is good, many questions still remain. For instance, the odd-Z iron-peak elements Sc, V, Mn, and Co together with neutron-capture elements Sr, Zr, La, Ce, Nd, Sm, and Eu have still unclear production sites because theoretical models and observational evidences are not in agreement. Having a

Poly (3-hydroxybutyrate) from a moderate halophile: production and modification for new applications

Popular Abstract in English Polyhydroxybutyrate (PHB) is a homopolymer belonging to the family of biopolyesters, polyhydroxyalkanoates (PHA) produced by different bacteria and archaea as intracellular granules often under conditions of metabolic stress due to a limited supply of essential nutrients. The properties of the PHAs are similar to those of polyethylene and polypropylene and can hence repPolyhydroxybutyrate (PHB) is a homopolymer belonging to the family of biopolyesters, polyhydroxyalkanoates (PHA) produced by different bacteria and archaea as intracellular granules often under conditions of metabolic stress due to a limited supply of essential nutrients. The properties of the PHAs are similar to those of polyethylene and polypropylene and can hence replace these fossil based poly

Higher Education for Girls in North American College Fiction 1886-1912

Popular Abstract in Swedish Från 1865 och framåt öppnades i nordöstra U.S.A ett antal college där unga kvinnor kunde avlägga en icke yrkesinriktad akademisk examen. Efter några decennier använde några som utexaminerats från dessa institutioner sina erfarenheter i populära berättelser om studenter på college. Avhandlingen visar hur denna utbildning presenteras i skönlitterär form. Fokus ligger på Twenty years after Vassar College welcomed the first American female undergraduates in 1865, the experiences of women college students began to be fictionalized in so-called college stories. This thesis shows how higher education is presented in the novels, collections of short stories, and serialized stories for female readers published before the United States was involved in the First World Wa

A multicentre study on the reliability of qualitative and quantitative nail-fold videocapillaroscopy assessment.

Objective. To investigate the inter- and intra-observer reliability of both qualitative and quantitative parameters used in the assessment of nail-fold capillaroscopy images.Methods. Fifty mosaic nail-fold images of healthy controls (n = 10), patients with primary RP (n = 10) and SSc (n = 30) were assessed in random order by two blinded observers on two occasions at centres in Sweden, UK and The N

Recurrence of Hyperprolactinemia after Withdrawal of Dopamine Agonists: Systematic Review and Meta-Analysis.

Context: Dopamine agonists are the treatment of choice for prolactinomas and symptomatic idiopathic hyperprolactinemia. However, the optimal treatment strategy and treatment duration is not clear in all details. Objective: The aim of the study was to assess the effect of dopamine agonist withdrawal in patients with idiopathic hyperprolactinemia and prolactinomas. Data Sources: PubMed, the Cochrane