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Much of biology happens at the protein-water interface, so all dynamical processes in this region are of fundamental importance. Local structural fluctuations in the hydration layer can be probed by 17O magnetic relaxation dispersion (MRD), which, at high frequencies, measures the integral of a biaxial rotational time correlation function (TCF) - the integral rotational correlation time. Numerous
We find ourselves in the midst of a remarkable technological revolution, with rapid advancements in fields such as artificial intelligence, robotics and information technology. Consequently, there is a pressing need for low-power technologies that are not reliant on continuous power supply. The field of spintronics aims to resolve this by coupling electric and magnetic properties. To pave the way
Background: Repolarization prolongation can be the earliest electrophysiological change in ischemia, but its role in arrhythmogenesis is unclear. The aim of the present study was to evaluate the early ischemic action potential duration (APD) prolongation concerning its causes, expression in ECG and association with early ischemic ventricular fibrillation (phase 1A VF). Methods: Coronary occlusion
Nearly 60% of the worlds adult population is projected to be overweight or obese by 2030. The prevalence of obesity- related diseases, such as type 2 diabetes (T2D), has increased markedly in the past decades. The adipose tissue plays an important role in disease progression of T2D. Adipocyte insulin sensitivity, adipose tissue’s ability to expand, and accumulation of subcutaneous rather than visc
Phytoglobins (Pgb) (plant hemoglobins) are heme-containing proteins and less well known in comparison to the mammalian counterparts hemoglobin (Hb) andmyoglobin (Mb). They share the same secondary structure as other globin-related proteins, six to eight α-helices comprising the myoglobin-fold (Mb-fold) with one prosthetic heme moiety per subunit. Pgbs are divided into different classes, where the Phytoglobins (Pgb) (plant hemoglobins) are heme-containing proteins and less well known in comparison to the mammalian counterparts hemoglobin (Hb) andmyoglobin (Mb). They share the same secondary structure as other globin-related proteins, six to eight α-helices comprising the myoglobin-fold (Mb-fold) with one prosthetic heme moiety per subunit. Pgbs are divided into different classes, where the
Background: Intra- and interfractional variations in anatomy can cause unplanned substantial alterations of the dose distribution of the target in proton therapy. Motion management methods might be used in order to minimize anatomical variations. In the proton therapy of lung cancer, a potential motion management technique is the use of the voluntary breath-hold approach. The aim of this study was
För att undersöka nanopartiklars toxicitet finns behov av att producera väldefinierade nanopartiklar dispergerade i en kolloid suspension. Men även för andra områden så som nanomedicin finns ett behov av denna typ av lösningar. För att dispergera partiklarna i vätska används ofta ytaktiva ämnen. När dessa ämnen tillsätts adderas de på ytan av partikeln och förändrar partiklarnas yta. Då forskning To examine nanoparticle toxicity there is a need to produce defined nanoparticles dispersed in a colloidal suspension. Such a solution could also be interesting for other fields such as nano-medicine. In order to disperse the particles in the liquid there are often surfactant added to the process that alternates the surface of the particles. As the research shows that the surface of a nanoparticle
Kan sorkar med mutationer slippa undan infektioner? Sjukdomar är ett av de största hoten som alla levande varelser kan utsättas för. Lyckligtvis har alla djur ett immunförsvar som försöker bekämpa dessa sjukdomar. Detta försvar består av många komponenter vars ritningar finns nedskrivna i DNA. Mutationer, som förändrar DNA, kan leda till olika variationer av en gen, och olika varianter kan påverk
Under de senaste decennierna har den personliga integriteten diskuterats i samband med flera lagstiftningsåtgärder i svensk rätt, inte minst i samband med ny lagstiftning inom straff- och straffprocessrätten. Flera straffrätts- bestämmelser har införts för att skydda den personliga integriteten mellan enskilda. Parallellt med denna utveckling har brottsbekämpande myndigheter tillgodosetts med nya In recent decades, personal integrity has been discussed in connection with several legislative measures in Swedish law, especially concerning new legislative measures in penal law and criminal procedure law. Several penal law measures have come into force to protect individuals’ privacy. At the same time, law enforcement agencies have been provided with new secret coercive measures which means th
Penningtvätt har länge varit ett uppmärksammat problem, men inte förrän på senare år, särskilt efter den 11 september 2001 och terroristattackerna i USA har stora krafttag gjort att bekämpningen av problemet kommit igång. Bekämpningen och förhindrandet av penningtvätt och finansiering av terrorism är även viktigt utifrån ett större perspektiv. Om man kan strypa finanserna för kriminell verksamhet,Money laundering has for a long time been an acknowledged problem, now more than ever. Especially after 9/11 2001 and the terrorist attacks in the USA, joint efforts have made combating the problem a serious matter. Combating and prevention of money laundering and terrorism financing is also important from a larger perspective. If you can close off finances of criminal activity, you are one step c
Life at a music festival can be both a blessing and a curse. It creates a feeling of escaping reality into euphoric happiness and freedom that only music festivals can bring. But one thing can drastically change this mood and make the living at the festival quite miserable – the weather. Rain as well as too high or low temperatures contribute to this negative change of mood. The festival chosen fo
Det pågår just nu en omställning från fossila till förnyelsebara energiresurser. Exempel på förnyelsebara resurser är sol-, vind- och vattenkraft. Problemet är att energiproduktionen är beroende av att solen skiner, vinden blåser eller att vattnet flödar. Lösningen kan vara att lagra energin i smältsalter. I det här projektet utvecklades metoder för att internt kunna studera smältsaltskorrosion avMolten salt applications are challenging from a material perspective. This degree project was carried out at Alfa Laval to give them a better understanding of the corrosion of solar salt on the standard heat exchanger material stainless steel 321. Similar tests have previously been performed externally. By developing test methods for in-house corrosion testing time and money can be saved. In thi
Högre verkningsgrader, stabilitet och minskad toxicitet; så skall framtidens solceller nå verkligheten. Många hoppas att solenergi ska ta över våra energibehov och varje dag närmar vi oss en grönare utvinning av elektricitet. Kommer våra bilar och byggnader täckas av solceller i framtiden? Inte helt omöjligt, om vi kan bemästra det fascinerande materialet perovskit. På EPFL, Ecóle Polytechnique FPerovskite research has quickly gone from non-existent to one of the biggest reseach areas in Photo- voltaics. There are still many questions to be solved regarding the stability, environmental impact, reproducible large area devices, efficiency and module fabrication cost of Perovskite Solar Cells, PSCs, before commercial up-scaling. Scientists all over the world are working towards solutions and
Over recent decades, use of insecticides to protect plants from pests and harmful insects have increased manyfold. Neonicotinoid insecticides, such as Imidacloprid (IMI) acts as partial agonists on nicotinic acetylcholine receptors which are widely present in both the central and peripheral nervous system of insects. Pollinators like Eristalis tenax are frequently exposed to these pesticides but h
High-order harmonic generation (HHG) is a highly nonlinear optical process in which extreme ultraviolet (XUV) radiation is generated due to the interaction of an intense laser field with atoms. This process enables the production of high harmonics, which would not be achieved with standard nonlinear media. The utilization of two-color laser fields (formed by combining a fundamental field with one
Title: The Role of Concept Stores: Consumer Perceptions of the Intended Brand Image Seminar date: 2024-05-30 Course: BUSN39, Degree Project in Global Marketing, Business Administration: Master Level Authors: Petra Ohlson & Emma Stenkil Supervisor: Ulf Johansson Research question: Why are fashion manufacturing brands opening concept stores? How does consumers' perception of the concept stor
Sveriges föreningskultur bidrar till att miljontals individer årligen får ta del av idrottens positiva effekter, såsom förhöjd fysisk och mental hälsa. Även samhället gynnas av en aktiv befolkning gällande exempelvis integration. Utan ideellt engagemang hade inte detta varit möjligt och det är därför av stor vikt att föreningsaktiva har tillgång till digitala verktyg som underlättar deras vardag oPromoting a healthy lifestyle through a user friendly website builder Sweden’s prominent sports club culture engages millions of people in an active lifestyle every year, benefitting both the individual and the society. Therefore, it is crucial to provide user friendly digital tools to help with administration of these associations. This master’s thesis has resulted in a digital tool that will h
Att mäta framgång i byggprojekt idag kan vara svårt. Dels att hitta en samsyn på vad framgång är dels hur man ska mäta framgång. Genom den forskning som finns inom området kan man konstatera att det är äldre metoder som används än idag för att mäta framgång. Dessa metoder har även modifierats med tiden och bildat nya metoder. De vanligaste områdena att mäta för att förstå framgång i forskning är tMeasuring success in construction projects today can be difficult—partly due to the lack of consensus on what success is, and partly due to the challenge of how to measure it. Existing research shows that older methods are still used to measure success, though many of these have been modified over time and evolved into new approaches. The most common aspects evaluated in research when measuring su
Fermentering av äpple - På gott och ont Fermentation, eller jäsning, av mat och dryck har varit känt under tusentals år. Fördelarna med fermenterade livsmedel är bl. a. att de blir mer lättsmälta, innehåller fler syntetiserade näringsämnen, minskar eller tar bort sjukdomsalstrande bakterier (patogener) samt ökar den probiotiska floran i tarmen. Under fermenteringen kan det skapas etanol - den mes
Sweden’s substantial building stock from the million programs is in need of renovations. These residential buildings were built without major attention to energy demand or architectural aesthetics. Until now, property owners have hesitated to carry out energy renovations due to the investment cost. The aim of this master thesis was to propose an energy-efficient renovation procedure whilst takin
