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BackgroundThe optimal ways of using aromatase inhibitors or tamoxifen as endocrine treatment for early breast cancer remains uncertain.MethodsWe undertook meta-analyses of individual data on 31 920 postmenopausal women with oestrogen-receptor-positive early breast cancer in the randomised trials of 5 years of aromatase inhibitor versus 5 years of tamoxifen; of 5 years of aromatase inhibitor versus

Automated cryptanalysis has seen a lot of attraction and success in the past decade, leading to new distinguishers or key-recovery attacks against various ciphers. We argue that the improved efficiency and usability of these new tools have been undervalued, especially for design processes. In this article, we break for the first time the classical iterative design paradigm for symmetric-key primit

The characteristics of an Elekta amorphous silicon (a-Si) electronic portal imaging device (EPID) in response to a 6 MV photon beam generated without a flattening filter, an unflattened beam, have been determined. The characteristics were then compared to those for a conventional photon beam generated with a flattening filter in the beam, a flattened beam, in order to determine the suitability of

The 4MOST consortium is currently halfway through a Conceptual Design study for ESO with the aim to develop a wide-field (>3 square degree, goal >5 square degree), high-multiplex (>1500 fibres, goal 3000 fibres) spectroscopic survey facility for an ESO 4m-class telescope (VISTA). 4MOST will run permanently on the telescope to perform a 5 year public survey yielding more than 20 million spectra at

This study aims to investigate and disentangle the impact of land use and climate variability on the Baltic Sea coastal zone from a millennial perspective. To assess the environmental status of the coastal zone we make use of siliceous microfossils (mainly diatoms), stable nitrogen and carbon isotopes, organic carbon accumulation rates, and lithological changes analyzed in a sediment core collecte

We report on measurements of the light absorption efficiency of InSb nanowires. The absorbed 70 fs light pulse generates carriers, which equilibrate with the lattice via electron-phonon coupling. The increase in lattice temperature is manifested as a strain that can be measured with X-ray diffraction. The diffracted X-ray signal from the excited sample was measured using a streak camera. The amoun

Turbulent flow through 90 degrees pipe bends, for four different curvatures, has been investigated using large eddy simulations. In particular, the origin of the so-called swirl switching phenomenon, which is a large scale oscillation of the flow after the bend, has been studied for different bend curvature ratios. A classification of the phenomenon into a high and a low frequency switching, with

Background: To investigate hand bone loss (HBL) measured by digital X-ray radiogrammetry (DXR) in patients with early rheumatoid arthritis (RA) receiving different treatment regimens, and to evaluate if DXR change rates during the first 12 months correlate with radiological damage after 24 months. Methods: From the total SWEFOT trial population, 159 patients had hand radiographs correctly timed an

Results from a Monte Carlo investigation are presented for the application of the dual photopeak window (DPW) scatter correction method to phantom geometries of varying shapes, sizes, and densities as well as to several collimators. A Monte Carlo program was used to simulate a Tc-99m point source at locations of 0.5 cm from the phantom surface, at the center, 0.5 cm from the bottom, and 4/5 the di

Rubidium concentrations in tissues of organisms (vascular plants, fungus, insect, bird, rodents) were closely related to soil chemical properties (K+ saturation as % cation exchange capacity, and pH) at repeated sampling of 30 beech forest sites in south Sweden. The Rb+ concentration of organisms, representing a variety of tropic levels, was a sensitive measure of the K+ status of acid soil ecosys

ZnWO4, ZnWO4 : Fe and ZnWO4 : Mo crystals were investigated by the methods of time-resolved spectroscopy in the temperature range of 4.2-300 K. It is shown that the Mo and Fe impurities significantly reduce the light yield of ZnWO4. The main 2.5 eV emission of ZnWO4 and the 1.77 eV emission band of ZnWO4 : Mo are shown to originate from the triplet excited state of the WO6 and MoO6 complex, respec

Background: The SIOP-Renal Tumor Study Group (RTSG) does not advocate invasive procedures to determine histology before the start of therapy. This may induce misdiagnosis-based treatment initiation, but only for a relatively small percentage of approximately 10% of non-Wilms tumors (non-WTs). MRI could be useful for reducing misdiagnosis, but there is no global consensus on differentiating charact

Aims: Peripheral artery disease (PAD) constitute a high-risk with adverse clinical outcomes. We aimed to investigate the cardiovascular outcomes following myocardial infarction (MI). Methods and results: This nationwide, Danish register-based follow-up study includes all patients experiencing an MI between 2000 and 2017. Patients with and without PAD were compared. Multivariable logistic regressio

The term bibliotherapy is well known in several scientific fields as well as among practitioners in the US and in the UK, but in Sweden there seems to be a more modest use of the term as well as presence of practical bibliotherapeutic activity. On the other hand, some of the effects of reading that are commonly associated with bibliotherapy in the scientific literature seems to be similar to the e

Det kan sägas att extraordinära rättsmedel och dess resningsregler i dagens rättegångsbalk 58 kap. härstammar från konungens förmånsrätt att bryta domar under 1100-talets högmedeltid. Begreppet rättskraft och behovet av att angripa lagakraftvunna domar slog inte igenom förrän i slutet av 1600-talet. Dåvarande regler tillämpades formellt inte vid brottmål, men kom ändå att i praktiken att göra det.One can say that the extraordinary remedies and their rules regarding the relief for a substantive defect in today’s Code of Civil Procedure (Section 58) originate in the king’s preferential right to annulate court decisions during the late middle ages in the 1100s. The concept of legal force and the need to impugn court decisions that have taken legal effect was not noticed before the end of the

This report has been conducted to examine the advantages and disadvantages of using an open system for experiments in the cone calorimeter with a vitiated air enclosure at low oxygen levels. Eight different experimental set-ups were conducted in which two were designed according to ISO 5660, i.e. the cone calorimeter in its standard configuration. In the other experimental set-ups, a chamber which

I övergången till en cirkulär ekonomi använder industrier i allt högre grad återvunnet material för att minska klimatpåverkan från sina produkter. Den ökade efterfrågan på återvunnet material drivs av både EU-direktiv och konsumenters preferenser. Både flask- och polyesterfiberindustrin ser potential i att möta EU:s krav och konsumenters efterfrågan genom att ersätta jungfruligt material med återvIn the transition towards a circular economy, industries are increasingly adopting recycled materials to decrease the climate impact of their products, driven by both regulatory requirements and consumer demand. The bottle and polyester fiber industries both recognize the potential to comply with EU policies and consumer preferences by replacing virgin material with recycled PET. Due to its desira

Klimatfrågan är ett ämne som många människor pratar om. De senaste årtiondena har klimatfrågan ökat i samband med ökade utsläpp. Effekterna av utsläppen är tydliga i form av höjda vattennivåer, värmeböljor, extremväder och skyfall för att nämna några. Vad människor gör åt saken beror mycket på hur medvetna människor är om klimatförändringarna. Vissa personer märker inte av klimatförändringarna medClimate change is an important topic for a lot of people and the usage of art to draw attention towards the issue is not a novel idea. Each art piece has had a different approach to, not only increase awareness but to also portray climate change. The expressions vary depending on who made the art piece, the context of its creation and similar parameters. Globally, this has been done since at least

Statistical modelling could be included in a betting strategy where the value of a bet is assessed by comparing model predictions and market odds. This thesis presents several models based on statistical learning methods for predicting the total number of corners in a football match. Generalised linear regression and decision tree models were developed and their profitability was examined by using