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Aromatase inhibitors versus tamoxifen in early breast cancer : patient-level meta-analysis of the randomised trials

BackgroundThe optimal ways of using aromatase inhibitors or tamoxifen as endocrine treatment for early breast cancer remains uncertain.MethodsWe undertook meta-analyses of individual data on 31 920 postmenopausal women with oestrogen-receptor-positive early breast cancer in the randomised trials of 5 years of aromatase inhibitor versus 5 years of tamoxifen; of 5 years of aromatase inhibitor versus

Probing cellulose–solvent interactions with self-diffusion NMR : Onium hydroxide concentration and co-solvent effects

The molecular self-diffusion coefficients were accessed, for the first time, in solutions of microcrystalline cellulose, dissolved in 30 wt% and 55 wt% aqueous tetrabutylammonium hydroxide, TBAH (aq), and in mixtures of 40 wt% TBAH (aq) with an organic co-solvent, dimethylsulfoxide (DMSO), through pulsed field gradient stimulated echo NMR measurements. A two-state model was applied to estimate α (

Long-Term Pattern of Psychotropic Medication Uses Among Swedish Parents of Children Diagnosed With Cancer

BACKGROUND: Parents experience a range of mental health disorders following their child's cancer diagnosis. It is thus essential to explore how the child's cancer diagnosis affects the dosage of psychotropic medication in both short- and long-term use, as well as potential disparities in utilization patterns between mothers and fathers.PATIENTS AND METHODS: Using Swedish registers, we identified a

The complexity of needs and roles of family members during breast cancer rehabilitation : a qualitative study

Background: Family members play a crucial role in supporting women with breast cancer during their recovery. In the complex situation of being an informal caregiver, their own health and ability to support the patient needs to be acknowledged. The aim was to explore the experiences, needs and roles of family members throughout the rehabilitation process of women with breast cancer. Methods: A qual

Assessment and empirical analysis of Finland emigration in response to Selected economic Pull-Push deriving forces: 1960-2008

The purpose of the study is to investigate the impact, in magnitude and direction, of some preliminary push-pull economic forces on the decision of Finland people to migrate to Sweden in the time period 1960-2009. It also aims to see how different people respond to those forces active based on their sex, marital status and age, 15-30 and 50-65 and strives to oversee which economic factors were mor

Utvärdering av "30 aspekter" En kvalitetskontroll av ett personlighetstest grundat på femfaktormodellen

The purpose of this investigation was to evaluate the personality questionnaire 30 aspects, which is based on the five-factor model. Our aim was to investigate the properties of the questionnaire through explorative factor analysis and reliability ratings. We also set out to explore the factor structure of the test to decide whether the instrument agreed with the five-factor model or not. The ques

Defining a reference building according to LEED v4, to enable comparison of LCA alternatives

In this thesis the possibility of defining a general reference building, or so-called Baseline Building representing Swedish multi-family dwellings is investigated. The scope of the research is limited to analyze the multi-family dwellings of 3-8 stories. If succeeded the results should represent a general Baseline Building according to the new LEED v4 credit, Building Life-Cycle Impact Reduction.

Millimeter Wave Antenna Array Calibration and Validation for 5G New Radio Access

This Master thesis work was performed in Ericsson AB, Lund. It studies and validates two classes of algorithms to be used in mm-wave massive MIMO antenna arrays, for their use in the future 5G mobile communication systems. The first class of algorithms relates to the calibration of the transceiver (TRX) chains responses of the antenna array and makes use of the antenna array mutual coupling, which

Divergence in coding sequence of different functional categories of immune genes between species of the order Rodentia

How mice avoid diseases, a measure of divergence The response we have to diseases vary from person to person. In much the same way diseases affect and are battled in many different ways depending on the species. This happens due to differences in their immune system. So, what causes these differences? Well, they are mostly caused by differences in the DNA, the molecule which has the code for ever

Är skatterätten rättssäker för småföretagare?

Skillnaderna mellan småföretag och större företags ekonomiska och organisatoriska förutsättningarna är både stora och förhållandevis tydliga. Dessa skillnader medför att småföretag är mer känsliga för brister i rättssäkerheten än större företag. Efter en undersökning av vilka hjälpmedel som finns till hands för småföretag att förstå skattelagstiftningen, så att de kan ta korrekta beslut, kan det kThe differences between small and large companies, both economically and organizationally, are large and relatively clear. These differences make smaller companies more susceptible to flaws in the rule of law. After investigation into what aid small companies can get to better understand and comply with the relevant tax laws, it can be concluded that more aid is needed. This is because as it now s

Molecular weight determination of Kraft lignin samples by Size Exclusion Chromatography

The valorization of lignin offers sustainable and renewable products and materials. For that reason lignin needs to be further analyzed although the various challenges this process implicates. The major obstacles in this field are lignin’s chemical heterogeneity, all the modifications in lignin’s chemical structure owing to its extraction method and purification process and the lack of appropriate

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Previous studies has concentrated around the area of children living with parents who has a alcohol problem, hence less research has focused on the children when they have become adults and moved away from home. I contacted a Danish organization, named Tuba, which provides free therapy to people, in the ages from 14 to 35, where one or both parents have an alcohol problem. In collaboration with Tu

Det du inte vet mår du dåligt av: En experimentell studie av uppmärksamhets bias hos ångestindivider

Syftet med den här studien var att undersöka ångests påverkan på uppmärksamhet. Deltagare med högt skattad ångest förväntades skilja sig åt från deltagare med lågt skattad ångest gällande deras uppmärksamhet. Deltagare förväntades skapa ett implicit minne för kombinationen av ansikten som presenterades för dem i experimentet. Ett modifierat dote probe test användes för att undersöka vad försöksperThe purpose of this study was to examine attentional biases in anxiety. Participants with high self-rated anxiety were predicted to differ in their attention compared to participants with low self-rated anxiety. Participants were predicted to have an implicit memory for the combination of faces that were used in the study. A modified dot probe task was used to examine high and low social and/or tr

En studie av momentumeffekter på OMXS30

This paper investigates the literature concerning market efficiency and how that compares to behavioral finance. The works of Fama (1970) who laid the ground for the efficient market hypothesis and Jegadeesh & Titman (1993) who laid the ground for momentum strategies are both analyzed and compared against each other. A momentum study on the weekly returns regarding the Swedish stock market (OM

Riskhantering vid byte av fast korsningsparti i spårväxel

Studien syftar till att öka kunskapen om riskerna som kan påverka tidsåtgången för underhållsarbete inom järnvägen, särskilt vid byte av fast korsningsparti i spårväxlar. Den tid som vanligtvis tillges vid underhåll ger inget utrymme för att oväntade händelser uppstår, därför är det av stor vikt att underhållet utförs effektivt för att slutföras inom tidsramen. Riskhanteringar utgörs av följande mThe study aims to increase knowledge about the risks that can affect the time required for maintenance work on railways, particularly when replacing fixed crossing sections in switches. The time allocated for maintenance usually does not allow for unexpected events, so it is crucial that maintenance is carried out efficiently to be completed within the timeframe. Risk management comprises the foll

Begränsandet av billighetsskälen och upprättelse för brottsoffer

I juli 2023 tillsatte regeringen en utredning i syfte att genomföra en övergri- pande översyn av straffskalorna samt lägga fram förslag till ett reformerat och mer rättvist påföljdssystem. Regeringen framhåller i direktivet att straffsyste- met bör uttrycka en tydligare klandervärdering av brottsliga gärningar för att undvika att brottsoffer upplever rättsprocessen som ytterligare en kränkning. DeIn July 2023, the Swedish government appointed an inquiry with the purpose of conducting a comprehensive review of the penalty scales and presenting proposals for a reformed and fairer penalty system. The government empha- sizes in the directive that the penal system should express a clearer condem- nation of the blameworthiness of criminal acts in order to avoid that victims experience the legal

Machine Learning-Based Estimation and Classification of Excreta Using Millimeter-Wave Radar

Otaliga mängder kritisk information om vår hälsa spolas ner varje dag. En toalettsits med osynligt inbyggd radar kan ta tillvara på denna information. Alla besöker toaletten varje dag, därav är den fylld av kliniskt relevant information, som hittills sällan använts för att övervaka hälsan. Förändringar i urin- och avföringsmängd, samt avföringens konsistens kan vara tidiga tecken på sjukdom, men rConstipation and irregular bowel movements are a daily challenge in elderly care, especially among patients with dementia who struggle to report their own toilet habits. This thesis investigates the possibility of using millimeter-wave pulsed coherent radar to passively monitor toilet visits and estimate both stool consistency and excreted quantity of urine and feces. This involved constructing a

Follow-up imaging after hospital discharge for acute intracerebral hemorrhage in European academic hospitals : a decision-making analysis

Purpose: To investigate factors guiding follow-up imaging after hospital discharge in atraumatic intracerebral hemorrhage (ICH) across large European academic centers and compare decision-making patterns using a standardized approach. Methods: Expert neuroradiologists from nine European centers in eight countries detailed their follow-up algorithms for deep and lobar ICH, specifying (1) patient-re