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In this economic evaluation, conducted alongside a randomized, double-blind clinical trial, economic data were collected from 339 patients with moderate-persistent asthma randomized to receive twice-daily, double-blind treatment with budesonide/formoterol 160/4.5 μg in a single inhaler (n = 166) or fluticasone propionate 250 μg (n = 173) for 12 weeks. The mean number of episode-free days (EFD) per

Imagine one Brit, one Dutch, two North Americans, one Spaniard and three Swedes setting up a joint international research project. Their areas of expertise vary: sociology, labour law and organisational theory. The scene is taking place in a hotel conference room in Uppsala. The North Americans are tired from the long trip and the jet-lag. The Spaniard arrived later than everybody, including himse

Background: Lanolin is often included when patch testing for common contact allergens. The clinical relevance of a positive patch test reaction to lanolin markers is, however, still a subject for debate. Objectives: To evaluate Amerchol L101 as a marker of lanolin allergy and investigate the clinical impact of lanolin-containing moisturizers on healthy and damaged skin using the repeated open appl

Cercozoa are abundant free-living soil protozoa and quantitatively important in soil food webs; yet, targeted high-throughput sequencing (HTS) has not yet been applied to this group. Here we describe the development of a targeted assay to explore Cercozoa using HTS, and we apply this assay to measure Cercozoan community response to drought in a Danish climate manipulation experiment (two sites exp

Quantitative proteomics plays an important role in validation of breast-cancer-related biomarkers. In this study, we systematically compared the performance of label-free quantification (LFQ) and SILAC with shotgun and directed methods for quantifying breast-cancer-related markers in microdissected tissues. We show that LFQ leads to slightly higher coefficient of variation (CV) for protein quantif

We here describe two proteomic datasets deposited in ProteomeXchange via PRIDE partner repository [1] with dataset identifiers PXD000484 (defined as "training") and PXD000485 (defined as "test") that have been used for the development of a tamoxifen outcome predictive signature [2]. Both datasets comprised 56 fresh frozen estrogen receptor (ER) positive primary breast tumor specimens derived from

Objective: To study whether serum levels of tumour necrosis factor-α (TNF-α), free or bound to etanercept, in biological-naïve adults with rheumatoid arthritis (RA) could predict the long-term efficacy of etanercept, measured as drug survival. Method: We identified 145 biological-naïve patients with RA starting treatment with etanercept at the Department of Rheumatology, Skåne University Hospital

Auger CVV spectra of simple metals are generally believed to be well described by one-electron-like theories in the bulk which account for matrix elements and, in some cases, also static core-hole screening effects. We present here detailed calculations on Li, Be, Na, Mg, and Al using self-consistent bulk wave functions and proper matrix elements. The resulting spectra differ markedly from experim

Syftet med denna studie är att ur ett sociologiskt perspektiv undersöka hur det är att bo i Barcelona och arbeta i ett internationellt callcenter som ung europeisk medborgare. Vad är det som motiverar individer att migrera och arbeta i Barcelona? Hur upplever de förutsättningar i arbetet, social gemenskap och hur uppfattar de sin tillhörighet? Dessa frågeställningar sätts sedan i en bredare kontexThe aim of this study is from a sociological perspective understand how it is to live in Barcelona while working in an international call centre as a young European citizen. What motivates these individuals to migrate to Barcelona? What is their perspective of work, social community and notion of belonging? These questions are later to be examined together with theories of migration, modernization

Since the birth of the industrial revolution, there has existed a fear of becoming redundant and unemployed due to technological development. However, this has not been the case, but the last decades have instead seen the surge of income inequality. This has been linked to the growing technology bias towards skilled workers. This paper studies if the interactive effect of technological development

Prisons encourage criminal activity and have negative impacts on sentenced individuals according to studies. Meanwhile the three largest political parties in Sweden work towards implementing tougher sentences. The three largest parties have in common their position on law enforcement which disputes what the research is saying and as a consequence, the objective of achieving less criminal activity

Amyloid beta (Aβ) proteins are a group of proteins able to form fibrillar aggregates that are linked to the adverse neurological effects seen in Alzheimer’s disease [11]. The molecular mechanisms that lead to the Aβ aggregation are complex processes, and efforts to understand them are being made by investigating the kinetics and thermodynamic properties of the protein. The solubility of the protei

This paper examines how the Covid-19 pandemic has affected Swedish corporate investments and if it differs from previous economic crises. By using data on total investments and investments made in digitalization and IT of Swedish businesses between 1986 and 2022, two time series regressions examine the impact of crises on investments. The results give support for both hypotheses implying that the

This master’s thesis aims to illuminate how the textile cultural heritage such as textiles and the documentation about textiles is currently preserved in archives. This is a field of study that is currently absent in the research of archival science and research in general. Three archives with material connected to textile cultural heritage were interviewed for this study. To answer how textile cu

The situation for the environment is in many ways dire. However, amidst all the negative environmental developments it is easy to neglect the successes that have actually happened. With the aim of better understanding what factors facilitated such a success this thesis analyses one such case, namely emissions of dioxins and chlorinated waste from the pulp and paper industry in Sweden. Dioxins were

Nik-related kinase: A New IL-10 Regulator Our body is constantly exposed to microscopic organisms called microbes. Some of these organisms are harmless while others are able to cause infection and damage. Thus, our body has defense mechanisms that include the immune system. Macrophages are cells that belong to the immune system and have key roles in defense against infection, wound healing, and r

In order to build an efficient transportation system of the future, public transport needs to be an attractive alternative offering a high quality travel experience. Future digital information systems for public buses will enrich the travelers experience by delivering relevant content - accurately on the right time and place. In this master thesis, design and implementation of an improved bus posi

Behövs kemiska bekämpningsmedel inom jordbruket? I Sverige finns ekologiska jordbruk, detta betyder bland annat att kemiska bekämpningsmedel inte används för att bespruta grödorna inom dessa jordbruk. Ekologiska lantbrukare använder sig istället av biologisk kontroll, vilket betyder att naturliga rovdjur till skadeinsekter introduceras i jordbrukslandskapet för att äta skadeinsekterna. För att unChemical pesticides have long been used to keep crops free from pests, but in modern agriculture biological control is viewed as a viable alternative to pesticides. The concept of biological control is to implement predators that feed upon the pests. It can however be difficult to follow the effects of the biological control in the field, which is why a theoretical mathematical model has been desi

Recent public opinion research and elite deliberation has established a particular interest in galvanizing an EU army to better enforce a sense of integration, stability and strengthin the Union. This article proposes an alternative mechanism, privileging Richard Rosecrance’s concept of the ‘virtual state’ as anequally important and worthyfactor contributing to all those aspects. The fourdefining