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Popular Abstract in Swedish Men älskar du honom? Så frågar en ung flicka på 1820-talet sin syster Henrietta som just skall gifta sig. Nej det gör Henrietta inte men hon böjer sig för den krassa verkligheten, behovet att bli försörjd. Den stillsamma frågan anger något som kan tolkas som en tyst revolution: övergången från en äldre syn på äktenskapet som ett ekonomiskt kontrakt till en uppfattning aThe main theme of this dissertation is the question of how young women in the early middle class handled the new demands for marriage based on love instead of on judgements of moral, economy and status. Another theme is the education of these middle class girls around 1800 and the question how this new education interacted with the new demands for love marriage. The German social historian Ulrike

Introduction: Soft tissue knee injury is a well-established and potent risk factor for development of knee osteoarthritis. However, there is a paucity of epidemiological data from the general population. Our aim was to estimate the annual person-level incidence for a wide spectrum of clinically diagnosed soft tissue knee injuries, and their distribution by age, sex, and season. Methods: In Sweden,

We followed-up for mortality and cancer incidence 1088 healthy non-smokers from a population-based study, who were characterized for 22 variants in 16 genes involved in DNA repair pathways. Follow-up was 100% complete. The association between polymorphism and mortality or cancer incidence was analyzed using Cox Proportional Hazard regression models. Ninety-five subjects had died in a median follow

Objectives To evaluate the real-life effect of an evidence-based Gold Standard Programme (GSP) for smoking cessation interventions in disadvantaged patients and to identify modifiable factors that consistently produce the highest abstinence rates. Design Observational prospective cohort study. Setting GSPs in pharmacies, hospitals and communities in Denmark, reporting to the national Smoking Cessa

Knowledge concerning the molecular mechanisms governing the influence of non-coding RNAs on protein production has emerged rapidly during the past decade. Today, two main research areas can be identified, one oriented toward the use of artificially introduced siRNAs for manipulation of gene expression, and the other one focused on the function of endogenous miRNAs. In both cases, the active molecu

This study investigates the mechanisms of (de)coding modality, focusing on the interpretation of utterances containing the modals must, may, måste, and kan. The main research question posed in this study is what enables the interlocutors to interpret modal expressions so that communicative goals are achieved. To answer this general question, Coates's (1983) study on modal contexts is initially rep

We present extensive density-functional theory (DFT) based calculations of the clean Rh(111) surface and of CO/Rh(111) overlayer systems. We study both ground-state structural properties and core-level shifts from differences in total energies at different coverages and adsorption sites. Most results are obtained using using norm-conserving or ultrasoft pseudopotentials. The overall reliability of

I-131 radionuclide therapy studies have not shown a strong relationship between tumor absorbed dose and response, possibly due to inaccuracies in activity quantification and dose estimation. The goal of this work was to establish the accuracy of I-131 activity quantification and absorbed dose estimation when patient-specific, 3-dimensional (3D) methods are used for SPECT reconstruction and for abs

We present extensive density-functional theory (DFT) based calculations of the clean Rh(111) surface and of CO/Rh(111) overlayer systems. We study both ground-state structural properties and core-level shifts from differences in total energies at different coverages and adsorption sites. Most results are obtained using using norm-conserving or ultrasoft pseudopotentials. The overall reliability of

Popular Abstract in Swedish Denna avhandling handlar om en grupp narkotikamissbrukare som gjort självmordsförsök. Såväl självmord som självmordsförsök är betydligt vanligare bland narkotikamissbrukare jämfört med totalbefolkningen. Bland vårdade narkotikamissbrukare är det mellan 19 till 47 procent som gjort självmordsförsök. Det höga självmordsförsökstalet bland narkotikamissbrukare förklaras oftThe aim of this thesis is to describe suicide attempts in a group of drug abusers who previously had received treatment of their addiction. Another aim is to interpret and analyse the life situations that the individual associates with the suicide attempt. The dissertation is based on interviews conducted on two occasions with 92 drug abusers, 62 men and 30 women. The majority of the drug abusers

The fire technical properties of products are determining factors for the initiation and growth of fires. Measurement of fire technical properties and the understanding of how they relate to real hazards are therefore important for fire safety. This work deals with the fire technical properties of building products, their tendency to ignite and release heat in different fire scenarios. Building p

The VDR is a prime candidate gene for osteoporosis. Here, we studied three common VDR haplotypes in relation to bone phenotypes in 5014 participants of the global MrOS Study. We also studied the relative expression of the haplotypes in human bone cells. One haplotype was associated with increased fracture risk and differently expressed in primary human bone cells. Introduction: Vitamin D plays an

The enrichment of Fe, relative to alpha elements such as O and Mg, represents a potential means to measure the ages of quasi-stellar object (QSO) host galaxies and probe nucleosynthesis in the early universe. QSOs exhibit prominent Fe II features and Mg II 2800 angstrom resonance doublet emission in the ultraviolet. Although chemical evolutionary models predict that the Fe/Mg abundance ratio decre

Introduction: Given considerable focus on health outcomes among childhood cancer survivors, we aimed to explore whether survivor bias is apparent during long-term follow-up of childhood cancer survivors. Methods: We identified all 1-year survivors of cancer diagnosed before 20 years of age in Denmark, Finland, Iceland, and Sweden. From the general population, we randomly sampled a comparison cohor

Inflammation and insulin resistance are associated with increased mortality in the general population. However, it remains unclear how physical activity and proinflammatory/hyperinsulinemic diets influence overall survival in prostate cancer patients. We analyzed 4779 men with nonmetastatic prostate cancer from the Health Professionals Follow-up Study. Postdiagnosis physical activity and diet were

Background: Registry data used to monitor clinical care need to be reliable, and the process for assuring data quality transparent. Here the auditing process of the Swedish quality registry for cardiac disease, SWEDEHEART, is described. Methods: SWEDEHEART audits have been performed at 4 time-points in 2011 to 2018, with data quality audited in the 3 largest subregistries covering acute coronary s

Our study aims to investigate the relationships of the major lineages within the moth family Geometridae, with a focus on the poorly studied Oenochrominae- Desmobathrinae complex, and to translate some of the results into a coherent subfamilial and tribal level classification for the family. We analyzed a molecular dataset of 1,206 Geometroidea terminal taxa from all biogeographical regions compri

AIMS: This nationwide study aimed to analyse the first 2 years of routine clinical use of cangrelor in all Swedish patients undergoing percutaneous coronary intervention (PCI). METHODS AND RESULTS: This observational Swedish Coronary Angiography and Angioplasty Registry (SCAAR) study identified 915 cangrelor-treated patients. As 899 were ST-segment elevation myocardial infarction (STEMI)-patients

Background: Chronic kidney disease (CKD) affects 6–10% of adults and often remains undiagnosed until advanced stages, leading to inadequate management. This study compared diagnosed, proxy-diagnosed, and undiagnosed CKD patients regarding prevalence, clinical assessment, nephroprotective treatment, healthcare utilization, and mortality. Methods: This retrospective observational study analyzed Regi

Objectives (1) To assess the risk of haematological malignancies in individuals with systemic sclerosis (SSc) compared with individuals without SSc; (2) to explore how the risk varies across groups stratified by sex and age; and (3) to determine when these malignancies present in relation to SSc diagnosis in a population-based setting. Methods We performed a nationwide cohort study using high-qual