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Aim: To study the relationship between hyperglycaemia and the onset/progression of retinopathy, blindness/moderate visual impairment or death, as well as the impact of improved glycaemic control on retinopathy in patients with non-insulin-dependent diabetes mellitus (NIDDM). Methods: Between January 1990 and October 1995 a total of 3,220 diabetic patients were enrolled in a programme for control

Under 1680-talet trädde Sophia Elisabet Brenner fram som poet och blev snart känd och uppskattad för sina dikter vid olika tillfällen i livet. Tillfällesdiktningen var en flexibel genre som gav henne möjligheten att resonera om tidens aktuella frågor, till exempel kvinnans ställning i äktenskap och samhälle eller värderingen av det som var gammalt och fornt och det som var nytt. Hennes rykte spred

Popular Abstract in Swedish Bakgrund Streptococcus pyogenes, eller grupp A streptokocker, är en av de vanligaste sjukdomsframkallande bakterierna hos människan. De orsakar ofta relativt harmlösa och lättbehandlade ytliga infektioner i hals (halsfluss) och hud (svinkoppor) men kan också ge djupare och livshotande infektioner. Dessutom förekommer följdsjukdomar efter infektioner med grupp A streptoPathogenic bacteria often produce potent proteases capable of destroying host tissue thereby providing the bacteria with tools for spreading and nutrient access. This thesis describes how group A, C and G streptococci can acquire surface bound protease activity through an alternative mechanism, namely by binding and activation of the human protease precursor plasminogen. Group A streptococci of c

Syftet med denna undersökning var att bestämma en 1 kg isvästs kylverkan på kroppen vid brandmansarbete. Testerna genomfördes i en klimatkammare, i en container med extrem strålningsvärme och i ett rökdykningshus med värme och tungt arbete. Den faktiska kylverkan mättes också med en termisk docka. Fyra erfarna brandmän deltog i försöken. I alla tester bar försökspersonerna standardklädsel för branThe aim of the present study was to examine the effects of wearing a light-weight ice-vest (1kg, water) on physiological and subjective responses in fire fighter’s work. The experiments were carried out in a climatic chamber, in a container under extreme radiant heat, and during simulated smoke-diving. In addition, the physical cooling effect of the ice-vest was measured with a thermal mannequin.

Introduction: Clinical trials have shown promising results for extended half-life factor VIII concentrates but little is known about individuals' valuation of haemophilia treatment attributes. Aim: To assess patient/caregiver and population valuation of treatment attributes of prophylactic regimens for people with severe haemophilia A. Methods: Members ≥16 years of the Swedish Haemophilia Society

The present work reports new experimental data for premixed flames of nitromethane, CH3NO2, at atmospheric pressure, and an evaluation of two contemporary kinetic mechanisms based on these new flame studies as well as previously published experimental data on laminar burning velocity and ignition. Flames of nitromethane + air at lean (ϕ = 0.8) and rich (ϕ = 1.2) conditions were stabilized on a fla

The classical tachykinin substance P (SP) has numerous potent neuroimmunomodulatory effects on all kinds of airway functions. Belonging to a class of neuromediators targeting not only residential cells but also inflammatory cells, studying SP provides important information on the bidirectional linkage between how neural function affects inflammatory events and, in turn, how inflammatory responses

Introduction: The central question this study sought to answer was whether the team members of Strategic Crisis Teams (SCTs) participating in mass-casualty incident (MCI) exercises in the Netherlands learn from their participation. Methods: Evaluation reports of exercises that took place at two different times were collected and analyzed against a theoretical model with several dimensions, looking

Existing researches on two-row film cooling mainly focused on double-jet film cooling. However, researches on the effects by combining different kinds of hole shapes on film cooling performance are quite limited. In order to improve the film cooling effectiveness, the three-dimensional numerical method is utilized to investigate the effects of a novel structure composed of two-row holes with diffe

BACKGROUND: Klinefelter syndrome (KS) is the most common sex chromosome disorder. The genetic background is the extra X chromosome. Venous thromboembolism (VTE) has been observed among KS patients. The aim of the present study was to examine whether KS is associated with VTE.METHODS AND RESULTS: We followed up all hospital in- and outpatients (N=1085) in Sweden with a diagnosis of KS between Janua

BACKGROUND: Protein S is an important regulatory protein of the coagulation cascade. The risk for venous thrombosis associated with protein S deficiency has been uncertain because all previous risk estimates used phenotypic evaluation alone, which can be ambiguous.OBJECTIVE: To quantitate the risk for thrombosis associated with a characterized protein S gene mutation that causes a Gly295-->Val sub

Popular Abstract in Swedish Polyklorerade bifenyler (PCB) är ett samlingsnamn för ett antal kemiska föreningar. De utmärker sig genom att de har en god elektrisk isoleringsförmåga och tålighet för höga temperaturer, och de har därför använts i bl.a. transformatorer och kondensatorer men även som mjukgörare i plaster och färger. Sedan det visat sig att exponering för PCB innebar allvarliga hälsoeff

Syftet med denna undersökning var att bestämma en 1 kg isvästs kylverkan på kroppen vid brandmansarbete. Testerna genomfördes i en klimatkammare, i en container med extrem strålningsvärme och i ett rökdykningshus med värme och tungt arbete. Den faktiska kylverkan mättes också med en termisk docka. Fyra erfarna brandmän deltog i försöken. I alla tester bar försökspersonerna standardklädsel för branThe aim of the present study was to examine the effects of wearing a light-weight ice-vest (1kg, water) on physiological and subjective responses in fire fighter’s work. The experiments were carried out in a climatic chamber, in a container under extreme radiant heat, and during simulated smoke-diving. In addition, the physical cooling effect of the ice-vest was measured with a thermal mannequin.

Breast cancer is the most common cancer in women worldwide, identification of new biomarkers for early diagnosis and detection will improve the clinical outcome of breast cancer patients. In the present study, we determined serum levels of vitronectin (VN) in 93 breast cancer patients, 30 benign breast lesions, 9 precancerous lesions, and 30 healthy individuals by enzyme-linked immunosorbent assay

Objective. Low molecular mass proteins (LMMP) are putative uraemic toxins, but their elimination is negligible in standard haemodialysis (HD). In this study, we used beta(2)-microglobulin, cystatin C and beta-trace protein, which differ in molecular mass and charge, to characterize the elimination patterns of three different dialysis modalities. Material and methods. Plasma samples were obtained a

We analyze cross correlations between price fluctuations of different stocks using methods of random matrix theory (RMT). Using two large databases, we calculate cross-correlation matrices C of returns constructed from (i) 30-min returns of 1000 US stocks for the 2-yr period 1994-1995, (ii) 30-min returns of 881 US stocks for the 2-yr period 1996-1997, and (iii) 1-day returns of 422 US stocks for

Popular Abstract in Swedish Värmebehandling (termoterapi) av tumör baseras på kunskap om den celldödande effekten av värme. Den har begränsats av svårigheten att kontrollera temperaturutbredningen så att en selektiv och tillräcklig effekt erhålls, och detta gäller särskilt djupt belägna tumörer. Interstitiell laser termoterapi (ILT) med Nd:YAG laser är en ny behandlingsform, som ger de tekniska föInterstitial laser thermotherapy (ILT) is a method well suited for selective local destruction of malignant tumours. In the present work, a laser thermotherapy system based on feedback temperature control of energy delivery (through computerised feedback system) was developed. Temperature control was excellent in experiments without carbonization and with preserved light penetration, whereas tempe

A part of this thesis has been devoted to present general recuperator technology such as available gas turbine recuperator types, applications where recuperators are utilized, recuperator materials etc. An investigation of some compact and highly efficient heat transfer surfaces, for intended use in gas turbine recuperators, include the following surfaces: · Cross Wavy (CW) primary surface. · Cor

Background/Aims: To identify prodromal Alzheimer's disease (AD) subjects using a data-driven approach to determine cognitive profiles in mild cognitive impairment (MCI). Methods: A total of 881 MCI subjects were recruited from 20 memory clinics and followed for up to 5 years. Outcome measures included cognitive variables, conversion to AD, and biomarkers (e. g. CSF, and MRI markers). Two hierarchi