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VETENSKAP OCH BEPRÖVAD ERFARENHET POLITIK VETENSKAP OCH BEPRÖVAD ERFARENHET VID SBU | 3 2 | STEN ANTTILA & SUSANNA AXELSSON VETENSKAP OCH BEPRÖVAD ERFARENHET POLITIK Förord 9 NILS-ERIC SAHLIN Tro eller vetande – vilken plats i politiken? 19 BARBRO WESTERHOLM Faktaförnekaren – är han/hon ett hot mot demokratin? 29 FINN BENGTSSON Kunskaper och evidens i politiken 41 DANIEL TARSCHYS Evidensbasering i
https://www.vbe.lu.se/sites/vbe.lu.se/files/vbe_politik_web.pdf - 2026-05-11
Genetic factors play an important role in the pathogenesis of osteoporosis by affecting bone mineral density and other predictors of osteoporotic fracture risk such as ultrasound properties of bone and skeletal geometry. We previously identified a polymorphism of a Sp1 binding site in the Collagen Type 1 Alpha 1 gene (COLIA1) that has been associated with reduced BMD and an increased risk of osteo
BACKGROUND: Permanent pacemaker implantation (PPM) early after cardiac transplantation has been shown not to predict a worse outcome. However, the requirement for pacing late after transplantation and its prognostic implications are not fully known. We describe the clinical indications, risk factors and long-term outcome in patients who required pacing early and late after transplantation.METHODS:
A decision is the result of comparing one or more alternatives with respect to one or more criteria that we consider relevant to the decision. Decision making can be considered as one of the most important challenges that analysts and experts encounter to solve complex problems. In recent decades, different methods and algorithms have been presented to support decision making. Multi-criteria analy
Tumor-associated macrophages (TAMs) are attractive targets for immunotherapy. Recently, studies in animal models showed that treatment with an anti-TAM antibody directed against the scavenger receptor MARCO resulted in suppression of tumor growth and metastatic dissemination. Here we investigated the expression of MARCO in relation to other macrophage markers and immune pathways in a non-small cel
Background: The risk of dementia is increased in patients with atrial fibrillation (AF). Objective: To study relevant co-morbidities and incident dementia (vascular dementia, Alzheimers disease, other dementia and all dementia) in AF patients. Methods: All adults (n = 537,513) ≥45 years diagnosed with AF in hospitals in Sweden 1998–2012 were included. Cox regression was used to estimate hazard rat
Background and purpose — The annual number of total knee arthroplasties (TKAs) has increased worldwide in recent years. To make projections regarding future needs for primaries and revisions, additional knowledge is important. We analyzed and compared the incidences among 4 Nordic countries Patients and methods — Using Nordic Arthroplasty Register Association (NARA) data from 4 countries, we analy
BACKGROUND The efficacy and effectiveness of the quadrivalent human papillomavirus (HPV) vaccine in preventing high-grade cervical lesions have been shown. However, data to inform the relationship between quadrivalent HPV vaccination and the subsequent risk of invasive cervical cancer are lacking. METHODS We used nationwide Swedish demographic and health registers to follow an open population of 1
The present series comprises all families (n = 77) with haemophilia B in Sweden and may be considered to be representative for the purposes of a population-based study of mutational heterogeneity. The 77 families (38 severe, 10 moderate, 29 mild) had 51 different mutations in total. Thirteen families had total, partial or small deletions, two had mutations in the promoter, eight families had splic
Background: Current information on the role of internists in the European countries is scarce. This report describes the results of a survey of the practice of internists in Europe. Methods: Two online questionnaire-based surveys were carried out by the European Board of Internal Medicine, one on the practice of internists and the other on postgraduate training in internal medicine. The national i
This study evaluated the effects of retinal ischemia-reperfusion (IR) injury and pre-treatment with the potent and specific aldose reductase inhibitor fidarestat on apoptosis, aldose reductase and sorbitol dehydrogenase expression, sorbitol pathway intermediate concentrations, and oxidative-nitrosative stress. Female Wistar rats were pre-treated with either vehicle (N-methyl-D-elucamine) or fidare
Background: Exhaled breath temperature (EBT) has been suggested as a marker of airway inflammation in asthma. Objectives: The aim of the present study was to investigate EBT in asthmatic subjects compared to healthy controls after an exercise challenge test, and in subjects with exercise-induced bronchoconstriction compared to subjects without, and to compare with body temperatures. Methods: A tot
PURPOSE: To evaluate patients' vision-related activity limitation before and after bilateral cataract surgery using the German version of the Catquest-9SF questionnaire. SETTING: Hanusch Hospital, Vienna, Austria, and Ophthalmic Clinic, Minden, Germany. DESIGN: Questionnaire development. METHODS: This prospective 2-center study included patients who were scheduled for bilateral cataract surgery an
Objective: To estimate the incidence of hospitalization for paediatric obstructive sleep apnoea syndrome (OSAS) or sleep-disordered breathing (SDB) caused by adenotonsillar or tonsillar hypertrophy without infection in children with a parent affected by OSAS. Patients and methods: Using the MigMed database at Lund University, hospital data on all children aged 0-18 years in Sweden between 1997 and
Background In ST-elevation myocardial infarction (STEMI), distal embolization of thrombus material often precludes restoration of normal coronary artery flow. Small-scaled studies have demonstrated that intracoronary thrombus aspiration improves flow and myocardial perfusion, but only one larger randomized single-center study has suggested a survival benefit. Thrombus aspiration is widely used in
Objective: The proteoglycan decorin stabilizes collagen whereas biglycan and hyaluronan disrupt well-organized collagen. The aim was to compare hyaluronan and proteoglycans in human fetal membranes obtained before and after spontaneous labour at term. Study design: Prelabour samples of fetal membranes (N = 9) were obtained from elective caesarean sections and regionally sampled from over the cervi
Abstract in French L’étude de l’effet d’amorçage syntaxique (syntactic priming) permet d’examiner la relation (potentielle) entre input et output dans l’interaction. On observe un effet d’amorçage lorsque la présentation d’un item (l’amorce) facilite le traitement ultérieur d’un item similaire (la cible). L’amorçage syntaxique ou structurel est un phénomène de réutilisation de la structure syntaxi
OBJECTIVE: To determine moment arm lengths from seven knee muscles and the patellar tendon. The knee muscles were the biceps femoris, semitendinosus, semimembranosus, gracilis, sartorius, and the lateral and medial gastrocnemius muscles. DESIGN: The moment arms were calculated based on MRI measurements. BACKGROUND: Moment arm lengths of different muscles with respect to the joint centre of rotatio
Meta Isæus-Berlin at Skissernas museum Many visitors will surely remember Ett vattenhem (A Water Home), five strikingly ambiguous furnished rooms set out on a low podium in the middle of the main walkway at the Bo01 Housing Fair in Malmö in 2001. The Hall and the Bathroom, at opposite ends of the long and narrow, windowless pavilion, were open to the world and visible from outside. The Bathroom
Popular Abstract in Swedish I denna avhandling presenteras en ny typ av röntgenkälla baserad på ett laser-producerat plasma. Röntgenstrålning alstras genom att fokusera laserpulser på ett strålmål. Energin i de enskilda laserpulserna blott är cirka 150 mJ, men tack vare den extremt korta pulstiden 100 fs (10E-13 s), blir laserns toppeffekt mer än 1 TW (10E12 W). Den extremt intensiva laserstrålninA laser-produced plasma was generated by focusing 100 fs laser pulses, with an energy of 150 mJ, onto metal targets. The laser intensity was expected to reach 10E17 W/cm2. Radiation was emitted from the created plasma, with photon energies extending up to the MeV regime. The laser-based X-ray source was optimised, with the purpose of making it a realistic source of hard X-rays (>10 keV). Dedicated
