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Objectives To study the effect of insulin treatment in combination with metformin or an insulin secretagogue, repaglinide, on glycaemic regulation in non-obese patients with type 2 diabetes. Design Randomised, double blind, double dummy, parallel trial. Setting Secondary care in Denmark between 2003 and 2006. Participants Non-obese patients (BMI <= 27) with preserved beta cell function. Interventi

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Written submissions or comments as a response on an EIS (Environmental Impact Statement) rank as one of the most common forms of public participation. Within public participation research there appears to be an international dearth of knowledge concerning such written submissions. The possible impact of such responses on an EIS is - with few exceptions - seldom put in focus. The aim in the present

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Context: MicroRNAs (miRNA) are noncoding RNAs that post- transcriptionally regulate gene expression. Their altered expression and function have been observed in most urologic cancers. MiRNAs represent potential disease biomarkers and novel therapeutic targets. Objective: To review and evaluate the evidence implicating miRNAs in the pathogenesis of prostate cancer (PCa), bladder cancer (BCa), and r

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Autism spectrum disorder (ASD) is a neuropsychiatric condition containing a large spectrum of developmental disorders. The diagnosed condition is increasing among people today. With this in mind, there is also a growing need for competence and experience with services and organizations providing care for this target group. The aim of this study was therefore to examine what competence and experien

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I november 2021 beslutade den dåvarande regeringen att tillsätta en utredning för att göra en översyn av regleringen om frihetsberövande påföljder för unga. I augusti 2023 publicerades utredningen som ställer sig positiv införandet av s.k. ungdomsfängelser. Den frihetsberövande påföljd som i nuläget finns för unga lagöverträdare (15–17 år), utöver fängelse, är sluten ungdomsvård (och stadgas i 32 In November 2021, the Swedish government at the time decided to appoint an inquiry to review the regulations on custodial sanctions for young people. In August 2023, the investigation was published, which is in favor of juvenile prisons. The custodial sanction that currently exists for young offenders (15-17 years old), in addition to imprisonment, is "closed youth care" (and is stipulat

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Att undersöka stjärnor i infrarött är en relativt ny företeelse till skillnad från optisk astronomi (dvs. synligt ljus). Det var först på 60-talet med teleskopet Stratoscope II som man lyckades få spektra från stjärnor i infrarött (våglängder på runt 3 m), och upptäckte förekomsten av vatten i kalla röda jättar. Den bakomliggade problematiken till varför modern infraröd astronomi är så ungt är våThe advent of infrared astronomy, unlike optical astronomy that was developed over centuries, was delayed until the space age due to our own atmosphere acting as an efficient shield towards this radiation. With a lot of molecules (including water) emitting in the infrared region, it was first in the late 1990s that water no longer was deemed special and was observed in many cooler (K-M) giant star

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Det är vedertaget i svensk rätt att avtal om framtida överlåtelse av fast egen- dom, såsom optionsavtal, är ogiltiga. En option är en rätt, men inte skyldighet, att i framtiden köpa eller sälja viss egendom. Även om det inte framgår explicit i lagtext eller förarbeten föreligger alltså i praktiken ett förbud mot option till fast egendom. Uppsatsens syfte är att granska huruvida det föreligger skälAgreements concerning future real estate transactions, such as option agree- ments, are invalid in the Swedish legal system. An option constitutes a right, but not an obligation, to buy or sell certain property in the future. There is a prohibition against option agreements to real estate, although it does not appear explicitly in the text of a law or the legislative history. The purpose of this t

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The purpose of this study was to investigate men's experiences of being subjected to domestic violence by their female partners, identify the consequences of this violence, and analyse barriers to seeking help or leaving the relationship. The goal is to understand the nature of the violence and its impact on the men involved. Two theories have been used to analyse the results: Goffman’s theory

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Titel: Cristiano Ronaldwho? En kvalitativ studie om esportatleter, de nya sportstjärnorna Seminariedatum: 2020-06-04 Ämne/kurs: FEKH29, Examensarbete kandidatnivå i marknadsföring, 15 högskolepoäng Författare: Victor Grundén, Christopher Kewenter och Isak Söderlund Schulz Handledare: Peter Svensson Fem nyckelord: Esport, esportatleter, esportfans, athlete branding och sports marketing Syfte:

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Barnkonventionens artikel 3 och 12 ger uttryck för två centrala principer inom barnrätten, vilka även är fastställda i andra svenska lagar som föräldrabalken och lagen med särskilda bestämmelser om vård av unga. Principen om barnets bästa innebär att vid samtliga åtgärder som rör barn ska barnets bästa vara avgörande. Vid denna bedömning ska varje barn få chansen att uttrycka sina åsikter, vilka s

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Buildings that are built and the asphalt that is used for the paving needs to be tested to see if they fulfill certain requirements and standards. These types of tests are performed at Peab’s technology centers/laboratories and it is in one of their labs in Helsingborg that the degree project has been executed. As soon as the laboratory gets a concrete sample, they are supposed to register it in t

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Hedersrelaterade våldsbrott är något som förekommer även i Sverige. Vi har dock ingen lagstiftning i Sverige som reglerar dessa brott. Begås ett våldsbrott där motivet varit hedersrelaterat, döms gärningsmännen i enlighet med de övriga våldsbrotten som regleras i 3 och 4 kap brottsbalken. Syftet med detta arbete är att undersöka vad bristen på lagreglering avseende de hedersrelaterade våldsbrotteHonor-related violence is something that also occurs in Sweden. However we have no legislation in Sweden that regulate these offenses. Committing a violent crime where the subject was honor-related, convicted offenders in accordance with the other violent crimes governed by Chapters 3 and 4 Penal Code. The purpose of this work is to investigate the lack of statutory regulation concerning the honor

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Background:Due to new legislation in 2011 and 2013, the Swedish public healthcare system has undergone change as regards incident reporting and supervision. Focus has turned to learning from adverse events and sharing this learning with actors within the system. The aim of this study was to explore with what underlying safety ontology adverse events in the incident reporting system are investigate

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Building regulations in Sweden require that an energy calculation is done for every building to show that the building design meets the maximum specific energy use as outlined in the Swedish Building Code. The result of this energy calculation is always one number, for example a building might use 89 kWh/m2 year when the building regulation requires 90 kWh/m2 year. This level of reporting can lead

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Abstract Abiotic environmental factors play a fundamental role in determining the distribution, abundance, and adaptive diversification of species. Empowered by new technologies enabling rapid and increasingly accurate examination of genomic variation in populations, researchers may gain new insights into the genomic background of adaptive radiation and stress resistance. We investigated genomic v

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Objective: The objective of this study was to compare short-term outcomes in patients who underwent thoracic endovascular aortic repair (TEVAR) with stent grafts alone or with a composite device design (stent graft plus bare-metal aortic stent) for acute type B aortic dissection in the setting of malperfusion. Methods: This retrospective analysis included patients with acute (≤14 days of symptom o

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The Neuregulin-ErbB4 pathway plays a crucial role in brain development and constitutes one of the most biologically plausible signaling pathways implicated in schizophrenia and, to a lesser extent, in bipolar disorder (BP). However, recent genome-wide association analyses have not provided evidence for common variation in NRG1 or ERBB4 influencing schizophrenia or bipolar disorder susceptibility.

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Background and purpose — Reported revision rates due to dislocation after hemiarthroplasty span a wide range. Dislocations treated with closed reduction are rarely reported despite the fact that they can be expected to constitute most of the dislocations that occur. We aimed to describe the total dislocation rate on the national level, and to identify risk factors for dislocation. Patients and met

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To preserve biodiversity and ecosystem services, company engagement is crucial. However, available data on manager views and perceptions regarding nature conservation in particular is rare. The presented survey data gives insights into current levels and forms of business commitments for nature conservation. The data contributes to understanding business attitudes towards voluntary conservation ac