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IMPORTANCE Moderate-grade adolescent idiopathic scoliosis (AIS) may be treated with full-time bracing. For patients who reject full-time bracing, the effects of alternative, conservative interventions are unknown. OBJECTIVE To determine whether self-mediated physical activity combined with either nighttime bracing (NB) or scoliosis-specific exercise (SSE) is superior to a control of physical activ

Background and objective: Patients diagnosed with grade group (GG) 1 prostate cancer (PCa) following treatment for benign disease (“incidental” PCa) are typically managed with active surveillance (AS). It is not known how their outcomes compare with those observed in patients diagnosed with GG1 on biopsy. We aimed at determining whether long-term oncologic outcomes of AS for patients with GG1 PCa

Importance: Circulating levels of neurofilament light (NfL) and glial fibrillary acidic protein (GFAP) are important in the course of brain injury in adults, but longitudinal postnatal circulating levels in preterm infants have not been investigated. Objectives: To examine postnatal longitudinal serum levels of NfL and GFAP in preterm infants during the first 15 weeks of life and to explore possib

BACKGROUND: Breast cancer in young adults has been implicated with a worse outcome. Analyses of genomic traits associated with age have been heterogenous, likely because of an incomplete accounting for underlying molecular subtypes. We aimed to resolve whether triple-negative breast cancer (TNBC) in younger versus older patients represent similar or different molecular diseases in the context of g

Background: Neuropsychiatric symptoms (NPS) are common in individuals with Alzheimer’s disease (AD) dementia, but substantial heterogeneity exists in the manifestation of NPS. Sex differences may explain this clinical variability. We aimed to investigate the sex differences in the prevalence and severity of NPS in AD dementia. Methods: Literature searches were conducted in Embase, MEDLINE/PubMed,

Background: Cognitive impairment is common following out-of-hospital cardiac arrest (OHCA), but the nature of the impairment is poorly understood. Our objective was to describe cognitive impairment in OHCA survivors, with the hypothesis that OHCA survivors would perform significantly worse on neuropsychological tests of cognition than controls with acute myocardial infarction (MI). Another aim was

This article presents a fully integrated millimeter-wave (mmW) transceiver front end covering 24.25–29.5 GHz. It features a wideband Doherty power amplifier utilizing adaptive bias and a transmit/receive switch (TRX-switch) that has embedded low noise amplifier to antenna matching. The phase shift of 90 $^\circ$ to

OBJECTIVE: To study intra-aneurysm sac pressure and subsequent abdominal aortic aneurysm (AAA) diameter changes in patients without endoleaks that remain unchanged in AAA diameter more than 1 year after endovascular aneurysm repair (EVAR). METHODS: A total of 23 patients underwent direct intra-aneurysm sac pressure (DISP) measurements 16 months (IQR: 14-35 months) after EVAR. Tip-pressure sensors

Previous studies have indicated that, during mechanical ventilation, an inspiratory pause enhances gas exchange. This has been attributed to prolonged time during which fresh gas of the tidal volume is present in the respiratory zone and is available for distribution in the lung periphery. The mean distribution time of inspired gas (MDT) is the mean time during which fractions of fresh gas are pre

Ett av sexualbrottslagstiftningens huvudsyften är att skydda barn och ungdomar mot sexuella övergrepp. Mot bakgrund av barns särskilda skyddsbehov har därför bestämmelser till skydd för barn under 15 år och mellan 15 och 18 år införts i brottsbalkens sjätte kapitel. Vad särskilt gäller i fråga om åldersrekvisiten föreskrivs genom bestämmelsen i 6 kap. 13 § BrB att till ansvar ska dömas även den soOne of the main objectives of the sexual offences legislation is to protect children from sexual abuse. In the light of children’s greater need for protection, special provisions concerning sexual offences against children have been incorporated into chapter 6 of the Swedish Penal Code. Regarding the prerequisites of age, the provision in chapter 6 paragraph 13 states that a person may face crimin

Varje år tvångsomhändertas tusentals barn av socialnämnden och placeras för vård enligt LVU i ett familjehem. Att tvångsvårda ett barn är mycket ingripande, men vad innebär egentligen ett sådant omhändertagande? Vad kan barnets familj göra och vad har socialnämnden för skyldigheter för att möjliggöra ett upphörande av vården? Ställs barnkonventionen mot EKMR i någon del av processen och vad innebäEach year, the social service forcibly places thousands of children for care within LVU in a foster home. To forcibly place a child for care is a very intrusive measure, but what does this placement really mean? What can the child’s family do and what obligations do the social service have for the care to cease? Is the convention on the rights of the child put against ECHR at any moment and what d

The cysteine proteases are enzymes found in every kingdom of life. Clan CA is the largest of the cysteine protease clans, with members all displaying a Cys/His/Asn(Asp) catalytic triad responsible for hydrolysing the peptide bond within the substrate. To regulate the activity of the proteases, another group of proteins act as natural inhibitors (cysteine protease inhibitors) and bind to the protea

Popular Abstract in Swedish Små partiklar i form av vätska eller fast material mellan 0.001 till 100 µm i diameter, kan sväva i luften och kallas då aerosolpartiklar. De påverkar direkt på klimatet genom att reflektera solstrålar ut till rymden. Detta gör att vi får ett kallare klimat. Indirekt kan de påverka klimatet genom att verka som kondensationskärnor vid molnbildning. Med detta påverkar de The aim of this work was to study atmospheric aerosols, focusing on the chemical composition, the morphology and the origin of the aerosol in the upper troposphere and lowermost stratosphere. An aerosol sampler was developed for this purpose. A new method for quantitative analysis of the major components of the aerosol, i.e. C, N and O was developed, and methodologies for single-particle analysis

In my paper I have emanated from the question when a refusal to deal by an undertaking in a dominant position constitutes an abuse according to article 82 EC Treaty. Article 82 of The Consolidated version of the Treaty establishing the European Community, signed in Rome 1957, incorporating the changes made by the Treaty of Amsterdam on 2 October 1997, OJ 1997 C340, pp. 173-308, hereafter referred

Introduction. The European Multiple System Atrophy-Study Group (EMSA-SG) is an academic network comprising 23 centers across Europe and Israel that has constituted itself already in January 1999. This international forum of established experts under the guidance of the University Hospital of Innsbruck as coordinating center is supported by the 5th framework program of the European Union since Marc

GENERAL AIM: To investigate how common single-nucleotide-polymorphisms (SNPs) that associate with cardiovascular disease (CVD) could be used in prevention and treatment of CVD. SUBJECTS: Subjects from the population-based Malmö-Diet-and-Cancer-(MDC)-Study (n=30447) and hypertensives from the Nordic-Diltiazem-(NORDIL)-Study (n=10881). METHODS AND RESULTS: A nine-SNP-lipid-genetic-risk-score was r

Peak aerobic power in humans ((V) over dot(O2), peak) is markedly affected by inspired O-2 tension (F-IO2). The question to be answered in this study is what factor plays a major role in the limitation of muscle peak. (V) over dot(O2) in hypoxia: arterial O-2 partial pressure (P-a,(O2)) or O-2 content (C-a,C-O2)? Thus, cardiac output (dye dilution with Cardio-green), leg blood flow (thermodilution

Popular Abstract in Swedish Alla levande organismer består av celler som tillsammans med molekyler generellt kallade extracellulär matrix bildar en vävnad. Celler innehåller fyra huvudgrupper av byggstenar: socker, fettsyror, aminosyror och nukleotider, vilka i tur och ordning bildar kolhydrater, fetter, proteiner och nukleinsyror. I vävnaderna pågår en ständig omsättning av byggstenarna och molek

BACKGROUND: Despite marked improvement in therapy and monitoring of patients with insulin-dependent (type 1) diabetes, diabetic nephropathy remains a serious complication, with subsequent end-stage renal disease in about 20% of cases. OBJECTIVE: To investigate in young patients with type 1 diabetes whether urine α-Glutathione S-transferase to creatinine ratio (α-GST:crea) relates to markers of s