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Group B streptococcal carriage in Sweden: a national study on risk factors for mother and infant colonisation

Background. To study group B streptococcus (GBS) colonisation in parturients and infants in relation to obstetric outcome and to define serotypes and antibiotic resistance in GBS isolates acquired. Methods. A population-based, national cohort of parturients and their infants was investigated. During 1 calendar week in 2005 all women giving birth (n=1,754) were requested to participate in the study

Different equations to combine creatinine and cystatin C to predict GFR. Arithmetic mean of existing equations performs as well as complex combinations

Purpose: To test various ways of combining creatinine and cystatin C in equations to predict glomerular filtration rate (GFR). Material and methods: Performance of the following expressions to predict GFR was compared with measured GFR (iohexol clearance, mL/min/1.73 m(2)) in 857 patients: (i) Lund-Malmo creatinine equation, (ii) Grubb cystatin C equation, (iii) arithmetic mean of (1) and (2), (iv

Transaction costs of Tradable White Certificate schemes: The Energy Efficiency Commitment as case study

This paper analyses the nature and scale of transaction costs (TCs) borne by obliged parties under a "Tradable White Certificate" (TWC) scheme. Taking the first phase of the Energy Efficiency Commitment (EECl) in Great Britain as a case study, several sources of TCs were considered, such as search for information, persuasion of customers, negotiation with business partners, and measurement and ver

Vinegar supplementation lowers glucose and insulin responses and increases satiety after a bread meal in healthy subjects

Objective: To investigate the potential of acetic acid supplementation as a means of lowering the glycaemic index (GI) of a bread meal, and to evaluate the possible dose - response effect on postprandial glycaemia, insulinaemia and satiety. Subjects and setting: In all, 12 healthy volunteers participated and the tests were performed at Applied Nutrition and Food Chemistry, Lund University, Sweden.

Comparison of temperature effects on soil respiration and bacterial and fungal growth rates

Temperature is an important factor regulating microbial activity and shaping the soil microbial community. Little is known, however, on how temperature affects the most important groups of the soil microorganisms, the bacteria and the fungi, in situ. We have therefore measured the instantaneous total activity (respiration rate), bacterial activity (growth rate as thymidine incorporation rate) and

Calcium mediated interaction of calf-thymus DNA with monolayers of distearoylphosphtidylcholine: a neutron and Xray reflectivity study

X-ray and neutron reflection studies, the latter in conjunction with contrast variation, have been combined to study the interaction of calf thymus DNA (ctDNA) with monolayers of distearoylphosphatidylcholine (DSPC) in the presence of 20 mM Ca2+ ions, at the air–liquid interface as a function of surface pressure (10, 20, 30 and 40 mN m−1). Analysis of the X-ray and neutron reflection data showed t

Effects of substrate concentration on methane potential and degradation kinetics in batch anaerobic digestion

In this study, two experiments were conducted to evaluate the impact of substrate concentrations on methane potential and degradation kinetics of substrate. The biochemical methane potential (BMP) tests in Experiment I were performed at a constant inoculum to substrate ratio (ISR), whereas, different ISRs were applied in Experiment II. Results obtained from Experiment I revealed that methane poten

The determination of plasmin and plasminogen-derived activity in turbid samples from various dairy products using an optimised spectrophotometric method

A spectrophotometric assay for plasmin and plasminogen-derived activity in dairy products was optimised and extended to determine plasmin and plasminogen-derived activity in turbid samples of dairy products. The method was validated by assessing reproducibility, repeatability, level of detection and recovery of plasmin activity in different sample matrices. Plasmin activity in raw milk was not aff

Different outcome of allogeneic transplantation in myelofibrosis using conventional or reduced-intensity conditioning regimens

Allogeneic haematopoietic stem cell transplantation remains the only curative treatment of myelofibrosis with myeloid metaplasia (MMM). Previous reports have indicated significant treatment-related mortality (TRM) for patients transplanted after myeloablative conditioning but superior survival has been reported after reduced-intensity conditioning (RIC). We report the results of a survey of all al

The revised Lund-Malmo GFR estimating equation outperforms MDRD and CKD-EPI across GFR, age and BMI intervals in a large Swedish population

Background: The performance of creatinine-based glomerular filtration rate (GFR) estimating equations may vary in subgroups defined by GFR, age and body mass index (BMI). This study compares the performance of the Modification of Diet in Renal Disease (MDRD) study and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations with the revised Lund-Malmo equation (LM Revised), a new equa

The liver in 30-year-old individuals with alpha(1)-antitrypsin deficiency.

OBJECTIVE. Severe (PiZZ) alpha(1)-antitrypsin (AAT) deficiency is a risk factor for liver disease, i.e. juvenile cirrhosis in infancy, and cirrhosis and hepatoma in adulthood. Little is known about the risk of liver disease in individuals with moderate (PiSZ) AAT deficiency. To investigate the natural course of AAT deficiency, a cohort of PiZZ and PiSZ individuals identified by the Swedish Nationa

The importance of the second hairpin loop of cystatin C for proteinase binding. Characterization of the interaction of Trp-106 variants of the inhibitor with cysteine proteinases

The single Trp of human cystatin C, Trp-106, is located in the second hairpin loop of the proteinase binding surface. Substitution of this residue by Gly markedly altered the spectroscopic changes accompanying papain binding and reduced the affinity for papain, actinidin, and cathepsins B and H by 300-900-fold. The decrease in affinity indicated that the side chain of Trp-106 contributes a similar

Enzymatic oil extraction and positional analysis of omega-3 fatty acids in Nile perch and salmon heads

The use of commercial proteases, bromelain and Protex 30L for oil extraction/recovery of polyunsaturated fatty acids (PUFA) from Nile perch and salmon heads was evaluated. Four phases were obtained after hydrolysis, oily phase, emulsion, aqueous phase and sludge. An increase in water content during the hydrolysis resulted in a decrease in oil yield. Maximum oil yield was obtained when hydrolysis w

Modelling Intensive Care Unit Length of Stay and Mortality Using Artificial Neural Networks

Föreställ dig att det går att förutse vistelsetid och överlevnad inom 30 dagar för en patient som läggs in på en intensivvårdsavdelning. Dessa mått kunnat bidra till en djupare förståelse för intensivvård. Dessutom hade dörrar öppnats för jämförelse av vårdavdelningar sinsemellan. I det här projektet har intagningsdata till intensivvårdsavdelningar, in- nehållande allt ifrån information om kroppstA large data set, consisting of 300 000 patients’ admission data to various intensive care units in Sweden, acquired from the Swedish Intensive Care Register, was used in this work. The aim was to enable accurate Length of Stay (LOS) and mortality within 30 days predictions by using feed-forward Artificial Neural Networks (ANNs). The LOS outcome was predicted as short versus long time stays, with

Nutrient Strategies for Carotenoid Enrichment in Hydroponic Lettuce

Vitamin A deficiency affects approximately 30% of children under 5 years old globally, with Bolivia showing persistent rates despite intervention efforts. High-altitude environments like La Paz present unique challenges for nutrient-rich crop production, mostly due to harsh growing conditions and limited infrastructure. This study investigated wether targeted modifications of hydroponic substrates

Strategy-for-education-2023-2024

Strategy for Education 2023–2024 Strategy for Education LUND UNIVERSITY | 2023–2024 3 STRATEGY FOR EDUCATION | 2023–2024 3 Lund University’s Strategy for First and Second-Cycle Education 2023–2024 Lund University’s Strategy for Education is based on the Platform for Strategic Work (STYR S2022/2375) and covers the prioritised areas in depth and the aspects that have been developed within them. Intr

https://www.lunduniversity.lu.se/sites/www.lunduniversity.lu.se/files/2023-06/strategy-for-education-2023-2024.pdf - 2026-05-11

Simultaneous energy and mass calibration of large-radius jets with the ATLAS detector using a deep neural network

The energy and mass measurements of jets are crucial tasks for the Large Hadron Collider experiments. This paper presents a new calibration method to simultaneously calibrate these quantities for large-radius jets measured with the ATLAS detector using a deep neural network (DNN). To address the specificities of the calibration problem, special loss functions and training procedures are employed,

The most common diagnoses in primary care, and changes over time, in the total population of Stockholm, Sweden

Objective: Primary care is the base in many health care systems, and to identify the most registered diagnoses in primary care is a way to identify the overall health care use and needs in society. We estimated the rates of the 30 most common diagnoses in primary health care and their male to female ratio. Research design and methods: This was a study including inhabitants 18 years and older out o

Access of medication review for people living with dementia : An analysis of inequality using Swedish register data

INTRODUCTIONThis study examines medication reviews (MRs) among people living with dementia (PWD) in Sweden, focusing on frequency and factors influencing access.METHODSUsing nationwide register data, all diagnosed PWD from 2010 to 2016 were assessed for MR receipt in 2015 and/or 2016. The analysis guided by the Andersen healthcare utilization framework, considered predisposing, enabling, and need-

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries : a multicentre, international, prospective cohort study

Background: Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anoma