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The view from below - a management system case study from a meaning-based view of organization

This paper reports on a case study, which investigated energy management and environmental management at a large-scale research facility. The author used the perspective of the managed personnel rather than the management, the entity or the management system. The focus of the research was on interpretation of work, particularly how employees' perceptions of priorities were affected by management i

Thermomechanical optimization of lightweight thermal protection system under aerodynamic heating

An optimization procedure has been established aiming to design an integrated thermal protection system (ITPS) with minimum weight. The objective of this research is to establish the procedure and ensure its effectiveness. A corrugated sandwich panel has been chosen as the optimization problem. The ITPS geometric dimensions are considered as the design variables. The objective function is the mass

Frequency- and Phase-Sensitive Magnetomotive Ultrasound Imaging of Superparamagnetic Iron Oxide Nanoparticles

It has recently been demonstrated that superparamagnetic iron oxide nanoparticles can be used as magnetomotive ultrasound contrast agents. A time-varying external magnetic field acts to move the particles and, thus, the nanoparticle-laden tissue. However, the difficulty of distinguishing this magnetomotive motion from undesired movement induced in regions without nanoparticles or other motion arti

A homozygous nonsense mutation (428G -> A) in the human secretor (FUT2) gene provides resistance to symptomatic norovirus (GGII) infections

Noroviruses (formerly Norwalk-like viruses) are a major cause of acute gastroenteritis worldwide and are associated with a significant number of nosocomial and food-borne outbreaks. In this study we show that the human secretor FUT2 gene, which codes for an alpha(1,2)-fucosyltransferase synthesizing the H-type 1 antigen in saliva and mucosa, is associated with susceptibility to norovirus infection

Test of Swedish anti-skid devices on five different slippery surfaces

The interest for effective preventive strategies for slips and falls is growing. Much remains to be done, however, to prevent slips and falls in the traffic environment. Some pedestrians are injured because of slippery pavements and roadways. Using an appropriate anti-skid device may reduce the risk of slips and falls on different surfaces outdoors during winter. The aim of this study was to evalu

Effects of exhaust gas recirculation at various loads on diesel engine performance and exhaust particle size distribution using four blends with a research octane number of 70 and diesel

Partially premixed combustion using gasoline-like fuels on compression ignition engines shows great potentials to break the soot-nitrogen oxides trade off and reduce both emissions simultaneously. By simply adjusting the dilution strategies and injection events, the control of partially premixed combustion is relatively easier compared to other low-temperature combustion concepts. However despite

A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease

High-profile studies have provided conflicting results regarding the involvement of the Omi/HtrA2 gene in Parkinson's disease (PD) susceptibility. Therefore, we performed a large-scale analysis of the association of common Omi/HtrA2 variants in the Genetic Epidemiology of Parkinson's disease (GEO-PD) consortium. GEO-PD sites provided clinical and genetic data including affection status, gender, et

Surviving in the Ashes : A Preliminary Assessment of Socio-Ecological Responses to a "Super-Eruption" in Foraging Southwest Japan (7,300 cal BP)

Major volcanic eruptions are one of the most devastating and unpredictable events for all societies past and present. Althoughmajor progress has been made by archaeologists in understanding volcanic impacts on past societies, almost all this work hasfocused on urban or settled agricultural societies. In contrast, there is a major gap in knowledge about how forager communitieswere able to respond a

Expansion of signal pathways in the ectomycorrhizal fungus Laccaria bicolor- evolution of nucleotide sequences and expression patterns in families of protein kinases and RAS small GTPases.

* The ectomycorrhizal fungus Laccaria bicolor has the largest genome of all fungi yet sequenced. The large genome size is partly a result of an expansion of gene family sizes. Among the largest gene families are protein kinases and RAS small guanosine triphosphatases (GTPases), which are key components of signal transduction pathways. * Comparative genomics and phylogenetic analyses were used to e

DGAT-onco : A differential analysis method to detect oncogenes by integrating functional information of mutations

It is a common strategy to predict oncogenes by differential analysis between somatic mutations and background mutations. Most previous methods only utilize mutations in the cancer population to model its background mutation, which have an obvious bias. A recent method, DiffMut, improves this issue by conducting differential mutational analysis with both mutations in the cancer population and the

Explaining high-diversity death assemblages : Undersampling of the living community, out-of-habitat transport, time-averaging of rare taxa, and local extinction

Molluscan benthic assemblages provide unique opportunities for understanding both spatial and temporal patterns of biodiversity. Species richness in the shell remains found at a site (i.e. the death assemblage) is typically several times higher than in the counterpart living assemblage, reflecting a complex history of settlement, dissemination and decomposition post-mortem. We used high-density te

Omega-3 fatty acids for inflamed depression - A match/mismatch study

Despite decades of research on the pathophysiology of depression, the development of new therapeutic interventions has been slow, and no biomarkers of treatment response have been clinically implemented. Several lines of evidence suggest that the clinical and biological heterogeneity among patients with major depressive disorder (MDD) has hampered progress in this field. MDD with low-grade inflamm

Ambient pressure operando catalytic characterization by combining PM-IRRAS with planar laser-induced fluorescence and surface optical reflectance imaging

We present a combination of optical operando techniques that allow us to bridge the pressure gap in heterogeneous catalysis. By combining Polarization Modulated - InfraRed Reflection Absorption Spectroscopy (PM-IRRAS) with two dimensional-Surface Optical Reflectance (2D-SOR) and Planar Laser Induced Fluorescence (PLIF), we can simultaneously measure the adsorbed species on the catalyst surface, mo

Comparison of four clinical risk scores in comatose patients after out-of-hospital cardiac arrest

Background and aims: Several different scoring systems for early risk stratification after out-of-hospital cardiac arrest have been developed, but few have been validated in large datasets. The aim of the present study was to compare the well-validated Out-of-hospital Cardiac Arrest (OHCA) and Cardiac Arrest Hospital Prognosis (CAHP)-scores to the less complex MIRACLE2- and Target Temperature Mana

Unequal excess mortality during the Spanish Flu pandemic in the Netherlands

A century after the Spanish Flu, the COVID-19 pandemic has brought renewed attention to socioeconomic and occupational differences in mortality in the earlier pandemic. The magnitude of these differences and the pathways between occupation and increased mortality remain unclear, however. In this paper, we explore the relation between occupational characteristics and excess mortality among men duri

Positioneringsmodul till omplanteringsrobot för skogsplantor

This master thesis is part of the development of a new industrial machine. The machine is a fully automated transplanting machine for the forest industry and will be used by nurseries around the world. Nurseries grow seedlings and sell them when they have grown enough to be planted in the ground. The machine being developed moves plants from a tray with small cells to a tray with bigger cells. Thi

Affekt Online: Effekt Offline - Om förtalsliknande företeelser av sexuell karaktär på en digital arena.

Antalet rättsfall gällande oönskad publicering och spridning av andra människors privata material på Internet har ökat betydligt de senaste åren, med de s.k. Instagramupploppen 2012 som en sorts uppmärksamhetskulmen. Inget svenskt samlingsnamn som passar i alla dylika sammanhang har uppkommit och även om specifika detaljer skiljer sig åt från fall till fall, förefaller ärekränkningar förekomma somThe legal cases concerning unwanted online publishing of private material have experienced a significant rise in the last few years peaking around 2012 in Sweden, with initial assiduities around the issue being brought about by the “Instagram riots”. Up to this day, there is yet to be a collective term to entirely encompass these cases, and although the specific details differ between each case, t