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Molecular phylogeny of north European Geometridae (Lepidoptera: Geometroidea)

A comprehensive phylogeny of north European Geometridae is reconstructed using a two-step analytical pipeline. First, a phylogenomic backbone tree was inferred using a 117-species subset of geometrid moths and a 35-species set of outgroup taxa from eight other macroheteroceran families. The data matrix totalled 209,499 bp from 648 protein-coding loci obtained using anchored hybrid enrichment techn

Rancidity development in oat during industrial processing

To improve the shelf-life of food products rich in lipids, it is important to minimize the lipid oxidation that occurs during processing, since this oxidation not only decreases shelf-life but also induces off-flavors. To evaluate the oxidation of lipids in the production of one β-glucan-rich and one protein-rich food supplement made from oats (Avena sativa), the neutral and polar lipid profile, h

Contractions of English semi-modals : the emancipating effect of frequency

GERMAN SUMMARY: Gegenstand dieser Arbeit sind die verkürzten Formen (Kontraktionen) der englischen Modalausdrücke (‘semi-modals’) 'BE going to', 'HAVE got to' und 'want to'. Die Kontraktionen sind in der gesprochenen Sprache häufig und zeigen sich in den Schreibweisen 'gonna', 'gotta' und 'wanna'. Sie werden im Nordamerikanischen Englisch untersucht. Den Hintergrund der Arbeit bildet die GrammThe current restructuring of the English modal system has long been noted as an ongoing language change process. Semi-modal constructions such as 'BE going to' and 'HAVE got to' are textbook cases of grammaticalization. As grammaticalization comes with a rise in frequency, these semi-modals are also typical examples of the ‘reducing effect’ of frequency, which leads to the contracted forms 'gonna'

Relationships Between Charlson Comorbidity Index Associated Biomarkers and Outcomes Among Participants in the Malmö Diet and Cancer Study

Introduction: The aim was to evaluate two biomarker scores trained to identify comorbidity burden in the prediction of specified chronic morbidities, and mortality in the general population. Methods: Cardiovascular biomarkers were measured in the cardiovascular cohort of the Malmö Diet and Cancer Study. A score of 19 biomarkers associated with Charlson Comorbidity Index (CCI) was created (BSMDC).

Exposure to unconventional oil and gas development and all-cause mortality in Medicare beneficiaries

Little is known about whether exposure to unconventional oil and gas development is associated with higher mortality risks in the elderly and whether related air pollutants are exposure pathways. We studied a cohort of 15,198,496 Medicare beneficiaries (136,215,059 person-years) in all major US unconventional exploration regions from 2001 to 2015. We gathered data from records of more than 2.5 mil

Tidal range and recovery from the impacts mechanical beach grooming

Mechanical grooming to remove litter and wrack from sandy beaches reduces strandline biodiversity. The impact of tidal range on recovery rates of strandline ecosystems after grooming has not been examined to date, even though tidal range is known to affect the spatial and temporal patterns of seaweed. We compared taxon richness of macroinvertebrates that occur all year round at 104 sites on two co

A diabetes-associated genetic variant is associated with diastolic dysfunction and cardiovascular disease

AIMS: Although the epidemiological association between Type 2 diabetes and congestive heart failure (CHF) as well as cardiovascular disease (CVD) is well established, associations between diabetes-related single-nucleotide polymorphisms (SNPs), CHF, and CVD have been surprisingly inconclusive. Our aim is to examine if 43 diabetes-related SNPs were associated with prevalent diastolic dysfunction as

Hepatopancreatoduodenectomy –a controversial treatment for bile duct and gallbladder cancer from a European perspective

Background: Hepatopancreatoduodenectomy (HPD) is an aggressive operation for treatment of advanced bile duct and gallbladder cancer associated with high perioperative morbidity and mortality, and uncertain oncological benefit in terms of survival. Few reports on HPD from Western centers exist. The purpose of this study was to evaluate safety and efficacy for HPD in European centers. Method: Member

Social skills training for attention deficit hyperactivity disorder (ADHD) in children aged 5 to 18 years

Background: Attention deficit hyperactivity disorder (ADHD) in children is associated with hyperactivity and impulsivity, attention problems, and difficulties with social interactions. Pharmacological treatment may alleviate the symptoms of ADHD but this rarely solves difficulties with social interactions. Children with ADHD may benefit from interventions designed to improve their social skills.We

Non-oral dopaminergic therapies for Parkinson's disease : current treatments and the future

Dysfunction of the gastrointestinal tract has now been recognized to affect all stages of Parkinson's disease (PD). The consequences lead to problems with absorption of oral medication, erratic treatment response, as well as silent aspiration, which is one of the key risk factors in developing pneumonia. The issue is further complicated by other gut abnormalities, such as small intestinal bacteria

Anti-Dumping Law of WTO/GATT and EC: Gradual Evolution of Anti-Dumping Law in Global Economic Integration

The aim of this study is to demonstrate and evaluate the current anti-dumping law as formed by the WTO/GATT law (GATT law) and implemented by the EC law against the background of global economic integration. Over centuries, international trade has involved a controversial business behaviour, “dumping”. Roughly speaking, a product is considered to be dumped if it is sold at a lower price abroad tha

The importance of social circumstances for Swedish women’s subjective well-being

The importance of social circumstances for middle-age women’s general subjective well-being (SWB) was investigated in a representative sample of Swedish women, age 43 (N = 369). The results showed non-existent to moderate relationships between a number of social circumstances variables and general SWB. The strongest relationship was found between marital status and global life satisfaction. Being

The dynamic structure of EF-G studied by fusidic acid resistance and internal revertants

We have previously identified 20 different fusidic acid-resistant alleles of fusA, encoding mutant forms of the ribosomal translocase EF-G. One of these, P413L, is used here as the starting point in selections for internal revertants, identifying 20 different pseudo-wild-type forms of EF-G. We have also identified two alleles of fusA previously isolated as suppressors of 4.5 S RNA deficiency. All

Doses to head and neck normal tissues for early stage Hodgkin lymphoma after involved node radiotherapy

Purpose To evaluate dose plans for head and neck organs at risk (OARs) for classical Hodgkin lymphoma (HL) patients using involved node radiotherapy (INRT) delivered as 3D conformal radiotherapy (3DCRT), volumetric modulated arc therapy (VMAT), and intensity modulated proton therapy (PT), in comparison to the past mantle field (MF). Materials and methods Data from 37 patients with cervical lymph n

The effects of in-car speed limiters – Field studies

Field trials in three European countries, the Netherlands, Spain and Sweden were carried out in order to investigate the effects of an in-car speed limiter. The trials were carried out on urban and rural roads including motorways. A so-called unobtrusive instrumented car was used, where all the measuring equipment was hidden. All the speed limit categories in the respective countries, ranging from

Revised systematics and higher classification of pierid butterflies (Lepidoptera Pieridae) based on molecular data

The butterfly family Pieridae comprises approximately 1000 described species placed in 85 genera, but the higher classification has not yet been settled. We used molecular data from eight gene regions (one mitochondrial and seven nuclear protein-coding genes) comprising a total of ~6700 bp from 96 taxa to infer a well-supported phylogenetic hypothesis for the family. Based on this hypothesis, we r

A portable and low-cost fMRI compatible pneumatic system for the investigation of the somatosensensory system in clinical and research environments

There still is a need for devices that allow reproducible stimulation of skin areas of the human body. We constructed a stimulation system and tested it by using brief pneumatic stimulation to the right thumb of nine healthy volunteers. BOLD-signals in response to tactile stimulation with frequencies of 1, 3 and 5 Hz were measured using a 3T MRI scanner. The stimulation device consists of syntheti

A Genotype-Dependent Intermediate ECG Phenotype in Patients With Persistent Lone Atrial Fibrillation Genotype ECG-Phenotype Correlation in Atrial Fibrillation

Background-Atrial fibrillation (AF) is heterogeneous at the clinical and molecular levels. Association studies have reported that common single-nucleotide polymorphisms in KCNE1 and SCN5A may predispose to AF In this study, we tested the hypothesis that specific AF-associated genotypes confer variation on the appearance of AF assessed by analysis of fibrillatory rate of the atria. Methods and Resu

Common marmosets are sensitive to simple dependencies at variable distances in an artificial grammar

Recognizing that two elements within a sequence of variable length depend on each other is a key ability in understanding the structure of language and music. Perception of such interdependencies has previously been documented in chimpanzees in the visual domain and in human infants and common squirrel monkeys with auditory playback experiments, but it remains unclear whether it typifies primates