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Popular Abstract in Swedish Beräkningar från Cancerfonden visar på att ungefär var tredje person i Sverige kommer att få en cancerdiagnos under sin livstid. Cancerceller är celler som har utvecklat speciella förmågor som gör att de har börjat dela sig ohämmat. Denna ohämmade celldelning leder till bildandet av en tumör och när tumören har nått ett visst stadie i sin utveckling så börjar den spridaAs a cancer grows it will, at a certain stage of disease progression, start spreading in the body. For several types of cancer this spreading will first occur through the lymphatic system and the first place where metastatic cell will be encountered is the first lymph node that drains the area where the tumor is located. This lymph node is defined as the sentinel lymph node (SLN). By analyzing the

Ditrysia comprise close to 99 % of all butterflies and moths. The evolutionary relationships among the ditrysian superfamilies have received considerable attention in phylogenetic studies based on DNA and transcriptomic data, but the deepest divergences remain for large parts unresolved or contradictory. To obtain complementary insight into the evolutionary history of the clade, and to test previo

The gelatinization of cassava, potato and wheat starches in supercritical carbon dioxide was investigated using light microscope. The starch was placed in a stainless steel chamber at atmospheric pressure and high CO2 pressures, 8 and 30 MPa as well as at 8 MPa N-2 and the gelatinization degree observed by light microscopy. The results showed that both pressure and supercritical fluid affected the

14-3-3 proteins comprise a family of highly conserved proteins. 14-3-3 proteins have been found in all organisms examined except for members of the prokaryotic kingdom. 14-3-3s are involved in numerous processes in the cell and they typically bind to phosphorylated motifs in other proteins and regulate their activities. In plants, 14-3-3 proteins are recognized as key regulators of primary metabo

Frågan om bevisning utgör en viktig fråga även i skiljeförfaranden. I synnerhet skriftlig bevisning är viktig då den överlag anses vara mer tillförlitlig än muntlig sådan. Det är därför av vikt att part får tillgång till all skriftlig bevisning, även sådan som motpart eller annan kan tänkas inneha. Om dessa dokument frivilligt företes av part eller tredje man uppstår inga problem. Problemen börjar

Myocardin-related transcription factors (MRTFs: myocardin/MYOCD, MRTF-A/MRTFA, and MRTF-B/MRTFB) are co-factors of serum response factor (SRF) that activate the smooth muscle cell (SMC) gene program and that play roles in cardiovascular development and mechanobiology. Gain and loss of function experiments have defined the SMC gene program under control of MRTFs, yet full understanding of their imp

Mutations are not identified in ~5% of hemophilia A and 10-35% of type 1 VWD patients. The bleeding tendency also varies among patients carrying the same causative mutation, potentially indicating variants in additional genes modifying the phenotype that cannot be identified by routine single-gene analysis. The F8, F9 and VWF genes were analyzed in parallel using an AmpliSeq strategy and Ion Torre

Hjärtsvikt betecknar ett syndrom som innebär att hjärtat har otillräcklig förmåga att försörja kroppen med blod. Detta kan antingen bero på att hjärtat inte kan fyllas med eller stöta ut tillräckligt med mängd blod. Patienter med hjärtsvikt har i allmänhet hög dödlighet, detta trots att stora framsteg har gjorts avseende behandlingen av hjärtsvikt, speciellt sedan 1980-talet. Femårsöverlevnaden föIntroduction: Despite major advances, the incidence rate and mortality of heart failure (HF) remains high, with a five-year survival of approximately 50%. At the time of inception of this thesis the familial risks of HF, including the aspects of mortality, were largely underdetermined. This thesis is composed of four papers with the main aims as follows:To determine the risk of hospitalization of

As the global power generation is shifted toward renewable and intermittent sources, the importance of fuel cells and other energy storage and conversion devices is continually increasing. However, many of these technologies are still under development and further research is necessary before they can be implemented. This is the case for the hydroxide exchange membrane fuel cell (HEMFC), which has

The aim of the study was to explore and describe spouses' experiences of participating in a case management intervention during older patients' fast-track programme having total hip replacement as well as which intervention elements they found useful. Data were collected through qualitative interviews with 10 spouses from the intervention group of the SICAM-trial, directed by predetermined codes b

The prevalence and incidence of doctor-diagnosed Dupuytren's disease in the general population is unknown. From the healthcare register for Skåne region (population 1.3 million) in southern Sweden, we identified all residents aged 3/420 years (on 31 December 2013), who 1998 to 2013 had consulted a doctor and received the diagnosis Dupuytren's disease (International Classification of Diseases 10th

Breast cancer is one of the most common cancers in women. It is most commonly treated by the surgical removal of the tumour in combination with (neo)-adjuvant therapy (hormone, chemo- or radio- therapy before or after surgery). However, a large number of patients are over treated, with approximately 60% being given adjuvant therapy when already cured by surgery alone. This causes many undesirable

Popular Abstract in Swedish Avhandlingen handlar om hur fett (lipider) i kosten bryts ner och transporteras i blodet för att slutligen antingen användas som energi, byggstenar i cellväggarna eller lagras i fettväven. I den här avhandlingen kan man också läsa om hur man kan modifiera fetter med hjälp av speciella proteiner: enzymer för att förbättra näringsinnehållet och dess fysikaliska egenskaperAn important indicator of the metabolic capacity of humans is the ability to regulate plasma triacylglycerol levels and to clear triacylglycerol-rich lipoproteins (TRLs) from the circulation after a meal. This is crucial since most of the day is spent in the postprandial state. High concentrations and long circulation times of TRL remnants may be detrimental since these are considered to be highly

In my thesis work I have explored the relationship between site and building. As the focal point for my studies I have had a, too me, very familiar site in the outskirts of the village of Höör in the centre of Skåne. e site has been the property of my grandfather who took care of the place until he got to old to do it. I spend a lot of time here when visiting my grandparents as a kid. Today my mot

Chemical Loping Combustion (CLC) is a novel combustion technology in which the exhaust gas is inherently divided into oxygen depleted air in one stream and CO2 and water vapour in another. This is however under the ideal condition that the fuel conversion is complete, i.e. all the hydrocarbons in the fuel is transformed to heat, water vapour and CO2. The CO2 capture rate can under such ideal condi

Reglerna som avser efterbehandling av förorenade områden finns i 10 kap miljöbalken (1998:808). Principen om att förorenaren betalar är en central princip som ligger bakom utformningen av dessa regler. Ett av principens syften är att säkerställa efterbehandling av förorenade områden utan att statsbudgeten belastas. Av 10 kap MB framgår att den som är primärt ansvarig för att avhjälpande sker är veThe regulations regarding remediation of polluted areas are found in the 10 chapter of the Swedish environmental code (Miljöbalk (1998:808)). The polluter pays principle is a central principle on which these regulations are based. One of the primary purposes with this principle is to ensure remediation of polluted areas without strain on the national budget. The primary liability lies with the so-

In this thesis, we focus on these three classes of objects: frieze patterns, polygon triangulations, and planar binary rooted trees. After proving that these objects are in pairwise bijective correspondence with each other, we introduce Catalan numbers through Dyck paths and prove that all these objects are Catalan objects. By studying the properties of triangulations and binary trees, we establis

Background and aim: The Barsebäck nuclear power plant (NPP) units ceased operations in 1999 and 2005. Now the NPP is in the phase of decommissioning, which is a complicated process that will take many years to complete. Radiological characterization of the surrounding area is a part of the decommissioning process. The aim of this thesis was to identify and quantify residual anthropogenic radioacti

As a result of climate change, temperatures have been steadily increasing in the last half century and extreme weather events such as storms, extreme heat, extreme precipitation and cold spells have been observed to occur more frequently. This comes with potential consequences for lives and health. There are several factors affecting the climate in a region. A phenomenon that has a large impact in