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Background: Developmental exposures to neurotoxic insecticides, as pyrethroids and chlorpyrifos are of growing concern. Objective: To study associations between low prenatal and childhood exposure to pyrethroids and chlorpyrifos and motor skills at age 7. Materials and methods: Data consisted of sub-samples of women and children from the Odense Child Cohort; 883 mother-child pairs with maternal ur

Background and Hypothesis: To clarify, in a large, representative, longitudinal sample, the rate and predictors of diagnostic conversion from Bipolar Disorder (BD) to Schizophrenia (SZ) and from SZ→BD. Design: From individuals born in Sweden 1950–1995 and living there in 1970 or later, we identified at least one initial diagnoses of SZ (n = 8449) and BD (n = 8438) followed for a minimum of 10 and

Background Functional Somatic Disorders (FSD) and Internalizing Psychiatric Disorders (IPD) are frequently comorbid and likely share familial/genetic risk factors. Methods We performed a Common Factor Multivariate Analysis of 2 FSDs, Fibromyalgia (FM) and Irritable Bowel Syndrome (IBS), and two IPDs, Major Depression (MD) and Anxiety Disorders (AD), in five kinds of Swedish female-female relative

Aims Cardiac telerehabilitation addresses common barriers for attendance at exercise-based cardiac rehabilitation (EBCR). Pragmatic real-world studies are however lacking, limiting generalizability of available evidence. We aimed to evaluate feasibility, safety, and patient perceptions of remotely delivered EBCR in a multicentre clinical practice setting after myocardial infarction (MI). Methods a

Although financial stressors are implicated as risk factors for suicidal behavior, these associations might be confounded by other factors. Furthermore, a move toward high-risk subgroup definition is necessary. The authors used Swedish national registry data to examine the associations between receipt of social welfare, unemployment benefits, or early retirement (N = 627,745-2,260,753) with suicid

The purpose of this project was to find estimates of the operational releases of 14C and 3H from new SMR technology that is being considered in Sweden, namely the Rolls-Royce SMR and the GE-Hitachi BWRX-300. To achieve this goal, models of the reactors of interest were made in the continuous-energy Monte-Carlo neutron and photon transport code Serpent, where the production of 14C and 3H could then

Background World economies increasingly rely on non-standard employment arrangements, which has been linked to ill health. While work and employment conditions are recognized structural determinants of health and health equity, policies aiming to protect workers from negative implications predominantly focus on standard employment arrangements and the needs of workers in non-standard employment ma

The understanding of genomics has improved tremendously during the last decades. The concept of recovery and outcome after stroke has also progressed during this time. However, the connection between genomics and stroke recovery has only begun to emerge in a more structural and comprehensive way. Different types of outcomes and recovery occur after stroke. This depends on domain of neurological de

Introduction: Inflammatory diseases have been associated with increased risk of venous thromboembolism (VTE). However, data on VTE is lacking in large population-based cohorts of microscopic colitis (MC). Methods: This study included all Swedish adults with incident MC without prior VTE (1990-2017; n=12,489; follow-up until 2021). MC and subtypes (collagenous colitis and lymphocytic colitis) were

OBJECTIVES: To compare the implementation of a co-created evidence-based injury prevention intervention with an existing program in youth team handball.DESIGN: Pragmatic two-armed cluster-randomized controlled trial, conducted collaboratively with the Swedish Handball Federation.METHODS: Eighteen clubs offering handball for female and male youth players (aged 12-16 years) were allocated randomly (

Introduction: Multidrug resistance (MDR) has been identified in wound bacterial isolates from Ukrainian war victims treated in Ukraine and across Europe. ILP100, a drug candidate for the treatment of skin wounds, is composed of a Limosilactobacillus reuteri expressing human chemokine CXCL12. In this study, the antimicrobial effects of ILP100 were tested on MDR bacteria isolated from wounds of Ukra

Tuberculosis (TB) remains a major public health challenge, with financial and health impacts extending beyond treatment. Both the perspective adopted in cost-effectiveness analyses-which critically determines choices such as the inclusion of patient-incurred costs-and the extent to which long-term post-treatment considerations are incorporated have important policy implications. This study examine

INTRODUCTION: Epidemiological studies focusing on the association of exposure to perfluoroalkyl substances (PFAS) with cardiovascular disease (CVD) morbidity and mortality are limited, with inconsistent findings.OBJECTIVES: This register-based study aimed to investigate the associations between exposure to PFAS and the risk of CVD morbidity and mortality in a Swedish population exposed to PFAS, do

Objectives: While high socioeconomic status (SES) indicators generally protect against mental health issues such as mood disorders in overall populations, evidence suggests that these protective effects might be attenuated for marginalized groups such as immigrants, in comparison to groups who are more socially privileged. This phenomenon is referred to as Marginalization-related Diminished Return

Purpose: To analyse risk of osteoporotic fractures in foreign-born individuals migrating to Sweden at different ages, compared to Swedish-born individuals. Methods: This was a nationwide open cohort study including individuals ≥30 years of age at baseline (N = 4,715,081). Foreign-born individuals were divided as having arrived to and being registered in Sweden from the ages 0–30 years of age or >3

Background: Exposure to per- and polyfluoroalkyl substances (PFAS) has been associated with lower bone mineral content (BMC) and density (BMD) in children, but prospective studies remain limited. We aimed to investigate associations between prenatal and childhood PFAS exposure and BMC/BMD at age 9 years, following up on our previous findings from age 7 years. Methods: We used data from the Odense