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The long-standing debate in the scientific community about whether ferroelectricity or ferroelasticity is the key property influencing the optoelectronic behavior of metal halide perovskites continues. In this study, we experimentally investigate the temperature dependence of photoluminescence from CsPb(Br1−xClx)3 nanowires and their heterojunctions. Our findings show an enhancement of the exciton
Cluster superlattice membranes constitute a novel 2D material, comprising a cluster superlattice sandwiched between a graphene support and an amorphous carbon embedding matrix. They offer a platform for investigating phenomena at the few atom to small cluster level with lateral averaging techniques. The amorphous carbon matrix provides mechanical and thermal stability to the cluster array, but alt
Objectives: 1. To validate catabolic meniscus explant models induced by cytokines: interleukin-6 + interleukin-6 receptor + tumor necrosis factor alpha (IL6/TNF) and oncostatin M + tumor necrosis factor alpha (OSM/TNF). 2. To evaluate three potential anti-catabolic treatments: i) dexamethasone (DEX), ii) a Link-N peptide (Link-N) and iii) a peptide from chondroadherin (CKF). Design: Healthy
Science, technology and innovation (STI) are widely perceived as critical factors for sustainable development. The 2030 Agenda defined STI as the central means of sustainable development. The Sustainable Development Goal 17 has three targets that focus on technology transfer, and the United Nations Technology Facilitation Mechanism was launched to promote multi-stakeholder collaboration. While STI
The aim of this study was to describe the extent to which men in psychiatric care have experienced emotional, physical, and sexual abuse during the life course and the association between this experience and being a perpetrator oneself. The aim was also to identify who exposed them to abuse and whether there was an association between the category of abuser and being a perpetrator oneself. A cross
Gold shell-isolated nanoparticles (AuSHINs) are promising photothermal therapy (PTT) agents for cancer treatment due to their excellent photoconversion efficiency, biocompatibility, colloidal stability, and tunable properties, including size, shape, and surface functionalization. However, their therapeutic efficacy in in vitro assays is often limited by poor cellular uptake and lysosomal entrapmen
Spark ablation is an advantageous method for the generation of metallic nanoparticles with defined particle sizes and compositions. The reaction of the metal particles with the carrier gas during the synthesis and, therefore, the incorporation of those light elements into structural voids or even compound formation was confirmed for hydrides and oxides but has only been suspected to occur for nitr
α-Synuclein is a synaptic protein that accumulates primarily in synucleinopathies and secondarily in certain lysosomal storage disorders. However, its physiological roles in health and disease are not fully understood. In part, this has been hampered by the inability to visualize α-synuclein and its cellular localization, due to the lack of specific antibodies and faithful reporters. Here, we used
The main purpose of this study was to examine the relationship between adult attachment, denoted as mental representations of childhood experiences, and social relations. A secondary purpose was to examine the impact of prematurity on attachment and social relations in adult age. The study is part of a larger longitudinal study carried out by professor Karin Stjernqvist and Anne-Li Hallin, candida
Swedish Development Cooperation emphasizes the need for collaboration among actors on a national level. In that context, the purpose of the thesis is to investigate how Public Private Partnership (PPP) on Corporate Social Responsibility (CSR) may influence the changing role of the state. The thesis is informed by Critical Discourse Analysis. In order to investigate the social constructions of real
Background: Epidemiological studies have indicated that physical activity reduces the risk of developing breast cancer. More recently, sedentary behavior has been suggested as a risk factor independent of physical activity level. The purpose of the present study was to investigate occupational sedentariness and breast cancer risk in pre- and postmenopausal women. Materials and methods: In a popula
In this study, aldehyde dehydrogenase 1 (ALDH1)-expressing cells in stroma of histologically normal breast tissue from premenopausal women were investigated in situ regarding cellular morphology, cell distribution, and relation to the additional stem cell markers, CD44 (+) and CD24 (-). These results were correlated with hormonal and genetic risk factors for breast cancer. Triple immunofluorescenc
The identification and validation of biomarkers for clinical applications remains an important issue for improving diagnostics and therapy in many diseases, including prostate cancer. Gene expression profiles are routinely applied to identify diagnostic and predictive biomarkers or novel targets for cancer. However, only few predictive markers identified in silico have also been validated for clin
Background The relationship between meniscal tears and other joint pathologies with patient-reported symptoms is not clear. We investigated associations between structural knee pathologies identified at surgery with preoperative knee pain and function in patients undergoing arthroscopic meniscal surgery. Methods This study included 443 patients from the Knee Arthroscopy Cohort Southern Denmark (KA
Stem cell engineering and grafting of mesencephalic dopamine (mesDA) neurons is a promising strategy for brain repair in Parkinson's disease (PD). Refinement of differentiation protocols to optimize this approach will require deeper understanding of mesDA neuron development. Here, we studied this process using transcriptome-wide single-cell RNA sequencing of mouse neural progenitors expressing the
Kraven på historisk rättvisa har intensifierats under de senaste decennierna. Sanningskommissioner, officiella ursäkter och ekonomiska ersättningar är nu vanliga sätt att bemöta människors vittnesmål om oförrätter i det förflutna. Tidigare forskning har fokuserat på uppgörelser med krig och kolonialism. I denna avhandling studeras gottgörelse för kränkningar i samband med sociala interventioner.I In 1999 the Swedish Parliament decided to provide economic compensation to victims of involuntary sterilization, and in 2012 a similar law was enacted to redress neglect and abuse in foster homes and orphanages. This study explores the dilemmas that arise with reparations for past injustices, focusing on the process leading up to the reparation laws. Four themes are investigated: [1] state redress
Background-Diabetes mellitus (DM) and cardiovascular disease are associated with dyslipidemia, but the detailed lipid molecular pattern in both diseases remains unknown. Methods and Results-We used shotgun mass spectrometry to determine serum levels of 255 molecular lipids in 316 controls, 171 DM, and 99 myocardial infarction (MI) events from a cohort derived from the Malmö Diet and Cancer study.
Red blood cell (RBC) traits are important heritable clinical biomarkers and modifiers of disease severity. To identify coding genetic variants associated with these traits, we conducted meta-analyses of seven RBC phenotypes in 130,273 multi-ethnic individuals from studies genotyped on an exome array. After conditional analyses and replication in 27,480 independent individuals, we identified 16 new
