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BACKGROUND: Global longitudinal strain (GLS) and left atrial strain metrics, including reservoir (LAr), contraction (LAct), and conduit strain (LAcd), have emerged as key indicators of left ventricular (LV) function and filling pressures. However, the prognostic value of these markers for risk stratification in acute heart failure (HF) remains uncertain, particularly in identifying patients at ele

Introduction: Sepsis, a widespread global ailment, involves an exaggerated immune response, leading to hyperinflammation and immunosuppression. Extracellular histones, released during hyperinflammation as part of the defensive response against pathogens, significantly contribute to sepsis pathogenesis, compromising viability of the host’s endothelial cells and contributing to organ failure. Method

Comparison of ROS production of individual particle components from traffic-related sources can inform new health policies and emissions legislation. This work aims to quantify acellular ROS production and oxidative potential (OP) of such individual particle components from combustion, brake, tire, and road wear. Particle characteristics are probed to identify source-specific markers and improve t

Carbon Black (CB), graphene, and nanodiamond are distinct carbonaceous insoluble nanoparticles. Reactive Oxygen Species (ROS) associated with these particles play a significant role in both in vivo and in vitro toxicity evaluations. Accurate assessment of ROS activity is relevant for toxicity screening and in ensuring safe working environments as well as guiding the innovation by safe-and-sustaina

Nearly 40 % of individuals will be diagnosed with cancer in their lifetime, translating to an estimated 20 million new cases annually. Despite remarkable therapeutic advances, only 15–20 % of patients achieve durable responses to immunotherapy, and the high cost of treatment (illustrated by immune checkpoint inhibitors like pembrolizumab and nivolumab, totaling roughly $191,000 per year) remains a

Coherent extreme ultraviolet (XUV) radiation can be generated in a tabletop configuration via high-order harmonic generation (HHG) in gases. While HHG is inherently inefficient, increasing the conversion efficiency (CE) is crucial for many applications, such as coincidence spectroscopy [1] and coherent imaging [2], which require high XUV throughput. Previous calculations suggest that one way to im

Intense ultrashort-pulsed laser systems based on Ti:sapphire chirped pulse amplifiers (CPA) operating at 800 nm have been a workhorse of ultrafast science for several decades. More recently, driven by the progress in laser technology, sources with central wavelengths further in the infrared have emerged as powerful tools, in particular to generate soft X-ray (SXR) radiation via high-harmonic gener

Background and objective: Prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) is an evolving diagnostic tool for prostate cancer. There is a need to harmonise existing guidelines and reporting recommendations for PSMA PET/CT. The Standardised PSMA PET/CT Analysis and Reporting Consensus (SPARC) project aims to consolidate classifications and recommen

LL_SMMV13_eng_HT20_rev_200422 Reading list for Introduction to Retail (SMMV13), 7,5 credits. The reading list was approved by the Board of the Department of Service Management and Service Studies 2019-04-24, revised 2020-04-22. The reading list is valid from 31 August 2020. Arnould, Eric J. (2005). “Animating the big middle”, Journal of Retailing, Vol. 81 No. 2, p. 89‐96. Ballantyne, David & Nilss

https://www.ses.lu.se/en/sites/ses.lu.se.en/files/ll_smmv13_eng_ht20_rev_200422.pdf - 2026-05-30

Microsoft Word - 3C12555D-2273-11F8.doc Lund University International Master’s Programme in Environmental Science Personal Transportation in Athens. Master’s Thesis By Yorgos K. VOUKAS Address: Evagelistrias 9 15342, Agia Paraskevi Athens, Greece Phone: +3 01 6080954 +3 0932 983066 E-mail: gvoukas@yahoo.com Supervisor: LUMES Eva Ericsson P.O Box 170, S-221 00, Lund Traffic Planning Tel: +46 (0) 46

https://www.lumes.lu.se/sites/lumes.lu.se/files/voukas_yorgos.pdf - 2026-05-30

Background and aim Sarcomas are of mesenchymal origin and typically show abundant tumour stroma and presence of necrosis. In search for novel biomarkers for personalised therapy, we determined the prognostic impact of stromal markers, hypoxia and neovascularity in high-grade soft tissue leiomyosarcoma and pleomorphic undifferentiated sarcoma. Method We evaluated CD163, colony-stimulating factor (C

Metabolomics is now widely used to characterize metabolic phenotypes associated with lifestyle risk factors such as obesity. The objective of the present study was to explore the associations of body mass index (BMI) with 145 metabolites measured in blood samples in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Metabolites were measured in blood from 392 men from t

The tremendous increases in production of plastic materials has led to an accumulation of plastic pollution worldwide. Many studies have addressed the physical effects of large-sized plastics on organisms, whereas few have focused on plastic nanoparticles, despite their distinct chemical, physical and mechanical properties. Hence our understanding of their effects on ecosystem function, behaviour

Genome-wide association studies have identified >50 common variants associated with kidney function, but these variants do not fully explain the variation in eGFR. We performed a two-stage meta-analysis of associations between genotypes from the Illumina exome array and eGFR on the basis of serum creatinine (eGFRcrea) among participants of European ancestry from the CKDGen Consortium (nStage1: 111

The cure rate of testicular cancer exceeds 95%, but testicular cancer survivors (TCS) are at increased risk of hypogonadism (HG). It has been suggested that TCS have reduced bone mineral density (BMD), but it is unclear whether this is related to HG or a direct effect of cancer therapy. The aim of this study was to evaluate whether TCS have decreased BMD, and if BMD is related to HG and/or the can

The aim of this study was to measure the impact of genetic data in improving the prediction of type 2 diabetes (T2D) in the Malmö Diet and Cancer Study cohort. The current study was performed in 3,426 Swedish individuals and utilizes of a set of genetic and environmental risk data. We first validated our environmental risk model by comparing it to both the Finnish Diabetes Risk Score and the T2D r

Increasing human impact on the environment is causing drastic changes in disturbance regimes and how they prevail over time. Of increasing relevance is to further our understanding on biological responses to pulse disturbances (short duration) and how they interact with other ongoing press disturbances (constantly present). Because the temporal and spatial contexts of single experiments often limi

Purpose: Personalized cancer treatment requires predictive biomarkers, including image-based biomarkers. Breast cancer (BC) patients receiving neoadjuvant chemotherapy (NACT) are in a clinically vulnerable situation with the tumor present. This study investigated whether mammographic density (MD), assessed pre-NACT, is predictive of pathological complete response (pCR). Methods: A total of 495 BC

Background: Patients with hand eczema often describe symptoms such as pain, clumsiness and difficulty flexing their fingers, thus impairing the function of the hand. Objective: The aim of this study was to investigate whether hand eczema is associated with a measurable impairment of hand strength and dexterity. We also studied the relationship between hand function and the ability to perform activ