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BACKGROUND: Matrilysin (MMP-7) elevation after radiotherapy is shown in humans. Matrilysin regulates certain cytokines and the production of bactericidal proteins when the mucosa is exposed to bacterial antigens. We investigate the effect of irradiation on matrilysin and microflora in murine bowel, after modulation with antibiotics. METHODS: Animals were divided into two different groups a radiati

We aimed to estimate stratified absolute (cumulative) and relative (standardized incidence ratios; SIRs) risks of non-Hodgkin lymphoma (NHL) in relatives of NHL patients. A cohort of 169 830 first-degree relatives of 45 406 NHL patients who were diagnosed between 1955 and 2010 in five European countries was followed for cancer incidence. The lifetime (0-79 year) cumulative risk of NHL in siblings

AIMS/HYPOTHESIS: Type 2 diabetes is a chronic metabolic disorder associated with devastating microvascular complications. Genome-wide association studies have identified more than 60 genetic variants associated with type 2 diabetes and/or glucose and insulin traits, but their role in the progression of diabetes is not established. The aim of this study was to explore whether these variants were al

Purpose: To assess performance of a biomarker-based score that predicts the five-year risk of diabetes (Diabetes Risk Score, DRS) in an independent cohort that included 15-year follow-up. Method: DRS was developed on the Inter99 cohort, and validated on the Botnia cohort. Performance was benchmarked against other risk-assessment tools comparing calibration, time to event analysis, and net reclassi

BACKGROUND: Stroke is common in cancer patients, but risk estimates for different cancer sites/types have not been determined. The aim of this nationwide study was to examine whether there is an association between cancer and first hospitalisation for haemorrhagic or ischaemic stroke. METHODS: All 820,491 individuals in Sweden with a diagnosis of cancer between 1st January 1987 and 31st December 2

This article presents a protocol for assessing team performance in terms of control based on cognitive systems engineering theory. The protocol changes the focus of team performance assessment from good and bad behaviours towards team activity. By using Hollnagel’s contextual control model (COCOM), a protocol is developed so that team activity can be described as four control modes. Data is collec

There are ethnic differences in the incidence of venous thromboembolism. This is the first nationwide study to examine whether there is an association between country of birth in first-generation immigrants and first hospitalisation for venous thrombosis (VT) and pulmonary embolism (PE), and to study whether a similar association exists in second-generation immigrants.

The incidences of both type 1 diabetes (T1D) and T2D are increasing worldwide. T2D is associated with many cancers. However, no data are available on cancer of unknown primary (CUP), a relatively common, fatal cancer for which tobacco smoking is the only known risk factor. At diagnosis, CUP metastases are found in various organs, which has implications for prognosis. We carried out a nationwide st

The archivist Martin Grass defines personal archives as that they do not have to adapt to guidelines when it comes to the culling or preservation of the material, the submitting of the material to an archive is not done directly after the material is created or collected and that they often concern broader subjects. In this thesis I study the creator of the personal archives and the driving forces

Reseavdraget – Motverkar det politiska spelet incitament som kan förbättra miljön? Reseavdraget, att vara berättigad till att dra av en del av kostnaderna som uppkommer till följd av resor till och från arbetsplatsen på skatten, har förundrat mig under flera år. Är reseavdraget rättvist utformat, belönar det ett samhällsekonomiskt olönsamt val eller kan det skapa incitament för arbetspendlare attIncome Tax-deduction for commuting expenses has been criticised and discussed for a long time without having reached any conclusions or reformations. Critical opinions in the debate are that a reformation would disfavour taxpayers living in the countryside with no options except car commuting and decreasing size of labour market regions. At the same time tax evasion is a huge problem because taxpa

Internet of Things (IoT) is network constituted by day-to-day objects equipped with some sensing system. These objects can also communicate with other objects for data exchange, wirelessly. This calls for a need of better wireless communication systems. New techniques using the 4G (Long-Term Evolution) have been developed to solve this problem, known as Advanced Antenna System (AAS). This new tech

This thesis is a discourse theoretical analysis of the European Unions foreign- and security policy. I use a discourse theoretical method inspired by Ernesto Laclau and Chantal Mouffe and use their concepts of nodal points, elements, moments and chains of equivalence. In my analysis I draw upon theories in relation to different kinds of power in international relations and especially in relation t

Video Sharing Websites constitute a rather peculiar situation. On one hand, they are considered as part of what the Commission perceives as online sharing economy: users are eligible to derive income from monetizing their audiovisual content. On the other hand, their business model is reminiscent of what is described as “free -economy”: access to the audiovisual content is prima facie provided wit

Gaming as a Service is not defined in existing research. The lack of a formal definition leads to an ambiguity between its function as a business model and the long-term strategy of the firm. The purpose and aim of this study is to investigate the definition of GaaS business model, distinguishing its function from the strategy. Furthermore, the key components of the model are established based on

Recent years has seen a growth of so-called ”Al-Qaeda franchises”, terrorist groups who formally ally with Al-Qaeda. This study investigates the phenomenon through how one such actor, the “Salafist Group for Preaching and Combat” (GSPC), has developed after its alliance with Al-Qaeda in 2006 and rebranding as ”Al-Qaeda in the Islamic Maghreb” (AQIM). By analyzing GSPC before and after the alliance

This project is a collaboration with Electrolux, KTH Royal Institute of Technology and the School of Industrial Design (Lund University). The goal of the project was to investigate new ways of cooling an individual, to ultimately result in a product proposal. We have all experienced heat waves in the summer, which can affect us even in our homes. In addition, typical home activities such as cleani

Sustainable development requires a change of values, norms, and capabilities within individuals and societies, and education is a crucial means to achieve these goals. However, transformation is not a simple task as dominant structures due to path-dependency and lock-in processes resist change, put pressure on innovative approaches, and hinder their potential for change. Thus the question is how s

So, what does a new life for the old fire station mean? It means that it is possible for a new generation to utilize the Gåsebäck landmark and historical building. The building should be attractive for the investors, for the city, and its inhabitants. The provided opportunities for the development of the building could be considered as a temporary solution for maintaining the history of the Gåsebä

In this master’s thesis I will investigate how librarians think about how their profession is affected by and relates to the democratic mission and various cultural policy decisions. I will also attempt to make more clear how librarians interpret, relate and deal with external forces of change such as technology, politics and other social forces. This has been done to investigate and survey the tw