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A demonstration of the theoretically predicted non-abelian properties of Majorana bound states (MBSs) would constitute a definite proof of a topological superconducting phase. Alongside the nontrivial braiding statistics, the fusion rules are fundamental properties of all non-abelian anyons. In this work, we propose and theoretically analyze a way to demonstrate MBS fusion rules in a Majorana sing
The prediction, identification, and characterization of phases away from equilibrium conditions remain difficult challenges for material science. Herein, we demonstrate how systems whose phase diagrams contain deeply incising eutectics can offer opportunities to address these challenges. We report the synthesis of a new compound in the Au-Si system, a textbook example of a system with a deep eutec
In this work, we report the aggregation-induced emission in a polymeric donor material poly(bis(2-butyloctyl)[2,2′:5′,2″-terthiophene]-4,4″-dicarboxylate-5,5′-diyl-vinylene) (PTVT-T), which exhibits a high device performance for the application of photovoltaics. Time-dependent density functional theory calculations and steady-state and time-resolved spectroscopy have been employed to reveal the un
Background: A growing body of evidence shows that prenatal exposure to phthalates affects child development. Since many phthalates have been shown to alter endocrine signaling, they may influence reproductive development, neurodevelopment, and child behavior. Indeed, a few studies reported associations between prenatal phthalate exposure and gender-specific play behavior. However, evidence for thi
Taking inspiration from Maria Lugones’ argument that “fragmentation [is] a form of domination” (1994, p. 464), this presentation discusses that ‘trans issues’ in schools are not restricted to transphobic comments, and need to be analyzed intersectionally. Normative whiteness and fat-phobia, as well as adultism and schools’ reluctance in instituting non-discrimination regulations reliable practices
Background and PurposeIn a previous study comparing the amount of visual field damage at presentation in patients having open-angle glaucoma (OAG) identified through screening and in patients diagnosed in routine clinical practice in the 1990s, the damage was considerably worse in the clinically diagnosed patients. In the present study we compare visual field damage at presentation in the same 402
Background: We aim to estimate population-attributable fractions (PAF) for 13 comorbidities potentially predisposing to hepatobiliary cancer of hepatocellular carcinoma (HCC), gallbladder cancer (GBC), cancers of the intrahepatic and extrahepatic bile ducts (ICC and ECC), and ampullary cancer. Methods: Patients were identified from the Swedish Inpatient Register from 1987 to 2018 and cancers from
Introduction: Lynch syndrome-associated cancer develops due to germline pathogenic variants in one of the mismatch repair (MMR) genes, MLH1, MSH2, MSH6 or PMS2. Somatic second hits in tumors cause MMR deficiency, testing for which is used to screen for Lynch syndrome in colorectal cancer and to guide selection for immunotherapy. Both MMR protein immunohistochemistry and microsatellite instability
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma frequently co-exist and share pathologic features. Taking a “global” treatment approach benefits diagnosis and treatment of both, but care is often siloed by specialty: joined-up clinics are uncommon. Our objectives were to explore expert opinion to give practical suggestions to identify adults needing global airways care; en
Objectives A novel longitudinal clustering technique was applied to comprehensive autoantibody data from a large, well-characterised, multinational inception systemic lupus erythematosus (SLE) cohort to determine profiles predictive of clinical outcomes. Methods Demographic, clinical and serological data from 805 patients with SLE obtained within 15 months of diagnosis and at 3-year and 5-year fol
Research continues to identify genetic variation, environmental exposures, and their mixtures underlying different diseases and conditions. There is a need for screening methods to understand the molecular outcomes of such factors. Here, we investigate a highly efficient and multiplexable, fractional factorial experimental design (FFED) to study six environmental factors (lead, valproic acid, bisp
Background: Temperament and character have been shown to be important factors in understanding psychiatric and neurodevelopmental disorder. Adults with autism spectrum disorder (ASD) have repeatedly been shown to have a distinct temperament and character, but this has not been evaluated in relation to psychiatric comorbidity and ASD diagnostic stability. Aims: To examine temperament and character
OBJECTIVE: To study the effect of methotrexate on male fertility and subsequent effects on their children, for which data are scarce and contradictory.DESIGN: Nationwide multiregister cohort study.SETTING: Not applicable.SUBJECT(S): All children born alive in Sweden between 2006 and 2014 and their fathers. Three cohorts were defined: children to fathers with periconceptional methotrexate exposure
BackgroundUniversity students experience a distinct working environment in the context of completing their studies. In line with existing research into the connection between workplace environment and stress, it is rational to believe that such study environments can affect the level of stress that students experience. However, few instruments have been developed for measuring this.ObjectiveThe ai
The food industry is actively adopting carbon neutral strategies aligned with the principles of Industry 4.0 to establish long-term goals for reducing carbon emissions and accelerating the transition to a low-carbon food production industry. Industry 4.0, often referred to as the fourth industrial revolution, emphasizes the integration of digital technologies, automation, and data exchange into ma
Mitochondrial dysfunction is a recognized factor in the pathogenesis of deep vein thrombosis (DVT). The role of 7S RNA, a long noncoding RNA that plays an important role in mitochondrial function, in DVT remains unclear. In this study, we aimed to investigate the potential use of 7S RNA as a biomarker in DVT. Plasma samples were obtained from 237 patients (aged 16-95 years) with suspected DVT recr
Growing evidence suggests that young migrants are particularly vulnerable to sexual violence. As young migrants often lack family and social networks, professionals are often the recipients of disclosures of sexual violence. This study aimed to explore how professionals experience young migrants’ disclosures of sexual violence. A qualitative design was used, based on 14 semi-structured interviews
Background: A diagnosis of prostate cancer (PC) may cause psychosocial distress that worsens quality of life; however, long-term mental health outcomes are unclear. Objective: To determine the long-term risks of major depression and death by suicide in a large population-based cohort. Design, setting, and participants: This was a national cohort study of 180 189 men diagnosed with PC during 1998–2
