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Popular Abstract in Swedish Bildning, bearbetning och upplagring av cathepsin G, proteinas 3 och azurocidin - närbesläktade bakteriedödande proteiner i vita blodkroppar Människans kropp utsätts dagligen för fientliga attacker av olika sorters mikroorganismer, tillhörande bakterie-, virus- eller svampsläktet. Så länge vi är friska och vårt immunförsvar fungerar, kan vi som tur är framgångsrikt föThe neutrophil granulocyte contains a number of multifunctional proteins stored in different subsets of granules. The azurophil granules, synthesized early during differentiation, harbour leukocyte elastase, cathepsin G, proteinase 3, and azurocidin; the members of the serprocidin family. In order to study the biosynthesis, processing, and intracellular sorting of the proteins, human cDNA encoding

Popular Abstract in Swedish Exponeringsskattning för att hindra uppkomst av belastningsskador Skador på muskler som uppkommer av olämpliga arbetsrörelser och arbetsställningar (belastningsskador) utgör ett stort problem i alla industrialiserade länder. Definitionen av vad som innefattas i begreppet arbetsskada varierar mellan olika länder, varför det är svårt att göra jämförelser. Kostnader för arWork-related musculoskeletal disorders of shoulder/neck are a major and increasing problem. Beside the pain, they involve high cost for the employer and society. The total expenditure for the musculoskeletal disorders of the neck and upper limb have been estimated to 0.5-2.0% of the Gross National Product (GNP) in the Nordic countries. Due to the lack of precise knowledge of exposure/response rela

Popular Abstract in Swedish Perifer kärlsjukdom (peripheral arterial disease) innebär ett tillstånd med nedsatt blodcirkulation i benen som huvudsakligen beror på åderförkalkning (ateroskleros). De kliniska manifestationerna av perifer kärlsjukdom är fönstertittarsjuka (claudicatio intermittens) och svår cirkulationsnedsättning (kritisk ischemi) beroende på om blodcirkulationen är otillräcklig vidPeripheral arterial disease (PAD) is the manifestation of atherosclerotic lesions in arteries supplying blood to the legs. Atherosclerosis is now recognized as an inflammatory disease of the vessel wall and important features in the pathophysiology are activation of WBC, endothelial cells and increased levels of inflammatory mediators. The inflammatory response in PAD is further influenced in case

Popular Abstract in Swedish Under de senaste åren har det svenska samhället förändrats när det gäller dess förhållande till religion och till Svenska kyrkan. Från att ha varit en statskyrka fram till år 2000 och därmed tidigare tillhört enhetskulturen och varit en majoritets kyrka, är Svenska kyrka idag en kyrka som är fri från staten och verkar i ett mångkulturellt samhälle där många olika kultur

Popular Abstract in Swedish Stroke är en vanlig och mycket allvarlig form av hjärt-kärlsjukdom som uppkommer på grund av försämrat blodflöde i en del av hjärnan. Eftersom hjärnan är extremt beroende av kontinuerlig tillförsel av syre och näringsämnen leder tillståndet snabbt till hjärnskada. Det finns tre typer av stroke; hjärninfarkt, hjärnblödning och subaraknoidalblödning (blödning under en hjäThe present thesis aimed to examine how ischemic stroke affects the vascular endothelin and angiotensin systems in cerebral arteries. To study vascular receptor changes in ischemic stroke transient focal ischemia was induced in rats. In addition, rat cerebral arteries and arterial smooth muscle cells were cultured for further analysis of cerebrovascular receptor regulation. For functional studies

The aim of the paper is to critically review the notion of social capital and review empirical literature on the association between social capital and health across countries. The methodology used for the review includes a systematic search on electronic databases for peer-reviewed published literature. We categorize studies according to level of analysis (single and multilevel) and examine wheth

The interferon inducible protein TRIM22 has been identified as a p53 target gene, with possible involvement in proliferation and differentiation of leukaemia cells. Here, the expression levels of TRIM22 during haematopoietic differentiation are characterised. Expression of TRIM22 correlates inversely to differentiation, as TRIM22 is highly expressed in CD34(+) human bone marrow progenitor cells, b

Popular Abstract in Swedish Stora förändringar har skett i jordbrukslandskapet under det senaste drygt halva århundradet. Ett allt intensivare jordbruk med krav på större skördar för att möta en allt större efterfrågan på livsmedel har satt sina spår. För att klara de högre kraven, men också som en följd av den teknologiska utvecklingen, så har jordbruket rationaliserats. Landskapet har strukturerAgricultural intensification has caused severe declines among biodiversity in European farmland over the last half century. The transformation of the agricultural landscape has led to reduced availability of key resources such as food, nesting habitat and shelter. In this thesis I have investigated a way of ameliorating the negative effects of agricultural intensification, through the creation of

Förevarande examensarbete syftar till att ge en överblick över rättsläget rörande förhållandet mellan intern rätt och skatteavtal med särskilt fokus på den situation då en samtidig tillämpning av skatteavtalet respektive den interna rätten leder till oförenliga följder (”normkollision”). Härvid behandlas bl.a. frågor rörande skatteavtalens rättsliga ställning i svensk rätt och hur man skall se på The objective of this thesis is to provide an overview of the legal position regarding the relationship between tax treaties and domestic law. The main focus is on the situation where the application of the domestic law and a tax treaty leads to irreconcilable results (“conflict of norms” or “norm conflict”). In this respect, the thesis deals with questions regarding the tax treaty’s position with

BACKGROUND: Individuals with low income have poorer health and should, therefore, have higher health expenditure than people with high income particularly in countries with a universal health care system. However, it has been discussed if social inequities in health diminish with age and we, hence, aimed to analyse this question. METHODS: We performed an age stratified cross-sectional analysis usi

The implementation of biorefineries based on lignocellulosic materials as an alternative to fossil-based refineries calls for efficient methods for fractionation and recovery of the products. The focus for the biorefinery concept for utilisation of biomass has shifted, from design of more or less energy-driven biorefineries, to much more versatile facilities where chemicals and energy carriers can

The report presents a bibliography of academic literature on transdisciplinary urban research. It includes journal articles, book chapters, and reports that engage with a wide range of theories, methods, evaluation techniques, and experiences of academic and non-academic stakeholders who conduct collaborative research on or related to cities.

The aim of this report is to provide insights on the expertise, knowledge, and experiences of conducting transdisciplinary urban research. To gather insights, we developed a set of questions based on a review of transdisciplinary research publications from 2010 to 2023 in the disciplines of Architecture, Planning, Geography, Urban Studies, and Sustainability Science. We used these questions as a g

This report summarises the insights we developed by conducting a literature review of the dominant approaches and experiences of transdisciplinary urban research. We conducted a World Wide Web search to identify key academic and non-academic publications between 2010 and 2023 in the disciplines of Architecture, Planning, Geography, Urban Studies, and Sustainability Science. We focused on those con

This report provides a summary of 11 visualisations that have been developed by scholars who are engaged in transdisciplinary urban research. We identified the visualisations through a review of academic literature in the disciplines of Architecture, Planning, Geography, Urban Studies, and Sustainability Science between 2010 to 2023. Some of the visualisations are original while others are derived

Knowledge in statistics is essential to draw solid conclusions from data. This chapter covers the basic concepts needed to navigate in the world of biostatistics, with the aim that the reader should know what to search for when encountering new situations. First, the chapter introduces basic concepts such as scales of measurement, relation between sample and population, and features of stochastic

The use of ionizing radiation and radioactive substances for diagnostic, interventional and therapeutic procedures in health care provides benefits to millions of people each year. Since ionizing radiation also has harmful effects, a radiation protection approach is needed. The International Commission on Radiological Protection (ICRP) has formulated the primary aim of radiation protection in gene

The Swedish retail landscape is currently undergoing a transformative change with increased digitalization and a rapidly growing e-commerce sector, which creates both opportunities and challenges. The development towards omnichannel commerce creates a more complex customer journey and results in complex environmental challenges. E-commerce deliveries to consumers, in particular, pose a complex soc

SUMMARY: 1. Introduction. – 2. Local Self-government in the Swedish Constitution. – 3. The Legal Role and Activities of Local Government. – 4. Legal Supervision ofLocal Government. – 5. Swedish Local Government and the EU.