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The thesis aims to compare two approaches to psychosocial rehabilitation – day centres and clubhouses – and to explore if either appears better suited to support people in mental health recovery. The recovery focus is on opportunities for engaging in meaningful daily occupations, accessibility to social interaction and factors pertaining to perceived health and well-being. The thesis consists of f
The aim of this study was to investigate non-solvent precipitation of starch to produce nanoparticles that could be used in Pickering emulsions. The material used was waxy maize, modified with octenyl succinic anhydride. Different methods of non-solvent precipitation were investigated, and a method based on direct mixing of an 8% starch solution and ethanol (ratio 1:1) was found to produce the sma
Quantum chemical geometry optimisations have been performed on realistic models of the active site of myoglobin using density functional methods. The energy of the hydrogen bond between the distal histidine residue and CO or O2 has been estimated to be 8 kJ/mol and 32 kJ/mol, respectively. This 24 k J/mol energy difference accounts for most of the discrimination between CO and O2 by myoglobin (abo
Water exchange of tetraaquaplatinum(II) has been studies by use of high-pressure oxygen-17 NMR spectroscopy. Negative entropies and negative volumes of activation support associative activation. The tretraaquapalladium(II) complex reacts 1.4x10exp6 times faster than the corresponding platinum(II) complex.
Background: Chronic non-healing wounds present a substantial economic burden to healthcare system; significant reductions in quality of life for those affected, and precede often serious events such as limp amputations or even premature deaths. This burden is also likely to increase with a larger proportion of elderly and increasing prevalence of life-style diseases such as obesity and diabetes. R
Cerebrospinal fluid (CSF) biomarkers may support the diagnosis of Alzheimer's disease (AD). We studied if the diagnostic power of AD CSF biomarker concentrations, i.e., Aβ42, total tau (t-tau), and phosphorylated tau (p-tau), is affected by differences in lateral ventricular volume (VV), using CSF biomarker data and magnetic resonance imaging (MRI) scans of 730 subjects, from 13 European Memory Cl
Global warming and its effects on climate are of great concern. Climate change can affect buildings in different ways. Increased structural loads from wind and water, changes in energy need and decreased moisture durability of materials are some examples of the consequences. Future climate conditions are simulated by global climate models (GCMs). Downscaling by regional climate models (RCMs) provi
Crosslinked, cryostructured monoliths prepared from Lactobacillus reuteri cells were evaluated as potential immobilized whole-cell biocatalyst for conversion of glycerol, to potentially important chemicals for the biobased industry, i.e. 3-hydroxypropionaldehyde (3HPA), 3-hydroxypropionic acid (3HP) and 1,3-propanediol (1,3PDO). Glutaraldehyde, oxidized dextran and activated polyethyleneimine/modi
Background: Dosimetry in radionuclide therapy has the potential to allow for a treatment tailored to the individual patient. One therapeutic radiopharmaceutical where patient-specific dosimetry is feasible is 177Lu-DOTATATE, used for the treatment of neuroendocrine tumours. The emission of gamma photons by 177Lu allows for imaging with SPECT (single photon emission computed tomography). One import
Adaptation of crops to climate change has to be addressed locally due to the variability of soil, climate and the specific socio-economic settings influencing farm management decisions. Adaptation of rainfed cropping systems in the Mediterranean is especially challenging due to the projected decline in precipitation in the coming decades, which will increase the risk of droughts. Methods that can
Sweden’s “establishment reform” was introduced in 2010 with the ambition to increase the labour market participation of newly arrived migrants. It was in line with other labour market policies of the centre-right Alliance government, elected in 2006, which aimed to increase work incentives particularly for groups seen as “vulnerable” in, or excluded from, the labour market.By considering the histo
Introduction: Lobectomy is the standard curative treatment for non-small cell carcinoma (NSCLC) of the lung. Most studies on lobectomy have focused on short-term outcome and 30-day mortality. The aim of this study was to determine both short-term and long-term surgical outcome in all patients who underwent lobectomy for NSCLC in Iceland over a 24-year period. Material and methods: The study involv
Medulloblastomas comprise a heterogeneous group of tumours and can be subdivided into four molecular subgroups (WNT, SHH, Group 3 and Group 4) with distinct prognosis, biological behaviour and implications for targeted therapies. Few experimental models exist of the aggressive and poorly characterized Group 3 tumours. In order to establish a reproducible transplantable Group 3 medulloblastoma mode
In this study, a tank-connected food waste disposer system with the objective to optimise biogas production and nutrient recovery from food waste in Malmö was evaluated. The project investigated the source-separation ratio of food waste through waste composition analyses, determined the potential biogas production in ground food waste, analysed the organic matter content and the limiting component
