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Importance: The behavioral variant of Alzheimer disease (bvAD) is characterized by early and predominant behavioral deficits caused by AD pathology. This AD phenotype is insufficiently understood and lacks standardized clinical criteria, limiting reliability and reproducibility of diagnosis and scientific reporting. Objective: To perform a systematic review and meta-analysis of the bvAD literature
Background: Gallstones intervention during pregnancy might be a stressful event for both mother and fetus and stress might affect outcome. The aim of this study was to identify factors that might improve the care of pregnant patients in need of intervention for gallstone disease. Methods: By crossmatching the Swedish Registry of Gallstone Surgery and Endoscopic Retrograde Cholangiopancreatography
COVID-19 is a systemic disease, frequently affecting kidney function. Dexamethasone is standard treatment in severe COVID-19 cases, and is considered to increase plasma levels of cystatin C. However, this has not been studied in COVID-19. Glomerular filtration rate (GFR) is a clinically important indicator of renal function, but often estimated using equations (eGFR) based on filtered metabolites.
OBJECTIVE: Access to effective treatments for adolescents with depression needs to improve. Few studies have evaluated behavioural activation (BA) for adolescent depression, and none remotely delivered BA. This study explored the feasibility and acceptability of therapist-guided and self-guided internet-delivered BA (I-BA) in preparation for a future randomised controlled trial (RCT). DESIGN: A si
β-Mannan is abundant in the human diet and in hemicellulose derived from softwood. Linear or galactose-substituted β-mannan-oligosaccharides (MOS/GMOSs) derived from β-mannan are considered emerging prebiotics that could stimulate health-associated gut microbiota. However, the underlying mechanisms are not yet resolved. Therefore, this study investigated the cross-feeding and metabolic interaction
The issue of pharmaceutical pollution has recently gained attention on the international political agenda as several actors have raised concern for its negative impact on ecosystems, human health, and livelihoods in emerging economies where an increasing share of the pharmaceutical production is located due to the cheaper labor and less stringent environmental regulations. In 2019, the OECD publis
Forced air convection systems are the most preferred design of choice in many of the industrial-scale convection ovens. In this study, experimental investigation on convective heat transfer and mass transfer within a forced air convection oven was performed at different oven temperatures (100℃, 110℃ and 120℃) and at flow velocity (2 m/s, 3 m/s and 4 m/s) using potato slices (10*10*60 mm) as model
Antarctic krill, Euphausia superba, a polar ocean specialist, thrives in the Antarctic severe physical conditions. The krill life cycle consists of strategies that have enabled and supported the species’ dominance of the Antarctic Ocean. Sea Ice extent and duration creates condition that are crucial for survival of the Furcilia larvae. The species has flexibility to food resources and is omnivorou
Methane is a potent greenhouse gas that plays a major role in climate change. Significant uncertainty exists in the estimates of emissions from natural methane sources. This uncertainty in data is one of the primary scientific challenges in climate model. Geological seepage considered as the second largest natural source of methane after wetlands and today is recognized as a major contributor to a
Buildings are responsible for approximately 30% of global energy use, with HVAC systems accounting for 40% of that demand. Among these, data centers have become significant energy consumers, requiring highly efficient and stable cooling solutions. This project aims to explore data-driven control methods to improve the energy efficiency of data center cooling systems as well as reduce the effort an
This study presents a custom surface electromyography (sEMG) data acquisition system combining the TI ADS1299 analog-to-digital converter, Teensy MicroMod micro-controller, and a Python-based graphical user interface for real-time signal monitoring and guided data collection. The system outperformed the widely used Ninapro dataset across all major classification metrics, demonstrating improved cla
Steam and water chemistry is fundamental for most power generation on indus trial scale. This includes the dosing of chemicals, the monitoring of both water and steam, as well as understanding the underlying causes to diagnose eventual problems. Öresundsverket, which was designed for seasonal operation, now has to perform multiple starts per year and in meeting these demands there is a possi bilit
Osteoarthritis is a multifactorial degenerative disease characterized by the breakdown of articular cartilage (AC), affecting hundreds of millions of people worldwide. Among many treatment options, hydrogels have emerged as promising candidates for cartilage replacement, due to their structural resemblance to the native tissue. Hydrogels can be made from various materials, and this study focuses o
This thesis examines how autonomous buses are interpreted and evaluated as a potential mobility solution within a multi-level planning context involving both municipal and regional perspectives. While autonomous vehicles are often framed as a key component of future sustainable transport systems, their implementation depends not only on technological development but also on social acceptance, inst
This thesis aims to address a dual crisis. Globally, the construction industry relies on a linear “take-make-dispose” approach and a “tabula rasa” tactic in each novel project, draining the Earth’s resources. Locally, around a half of residential buildings in Riga, Latvia, are of Soviet mass housing typology. These structures are on the verge of structural expiration, at risk of progressive collap
Artificial intelligence (AI) is playing an expanding role in infectious disease surveillance and intervention planning by enabling analysis of large-scale health data. One of the key challenges in this area is to characterize transmission within households and to identify factors that influence both infectivity and susceptibility. The present study focuses on the COVID-19 pandemic, which not only
Since the Russian invasion of Ukraine in 2014, the EU and NATO have strengthened resilience, preparedness, and critical infrastructure policies in response to evolving transboundary threats. However, cascading climate risks, defined as cross-border and cross-sectoral impacts intensified by climate change, have the potential to be insufficiently understood and integrated into EU and NATO frameworks
Our way of handling the climate crisis is not fast or ambitious enough. We have the opportunity to plan for a better future, not just accept the consequences of our failure. To plan for a better future, we first need to conceptualise a vision of a desired end-point, in this case a climate-neutral and sustainable city. This essay is meant to inspire radical change by using and expanding the radical
