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The purpose of this perspective article is to critically explore the launch of the mission for 100 climate neutral cities in Europe. An overview of the mission approach in general is first presented, where key aspects and emerging critiques are identified. Second, key elements of the mission for 100 climate neutral cities in Europe are introduced along with some of its challenges and ambiguities.
Continuous monitoring of patients suffering from cardiovascular diseases and, in particular, myocardial infarction (MI) places a considerable burden on health-care systems and government budgets. The rise of wearable devices alleviates this burden, allowing for long-term patient monitoring in ambulatory settings. One of the major challenges in this area is to design ultra-low energy wearable devic
ad transport of dangerous goods is due to its inherent risk associated with a potential impact far higher than the small volumes might suggest, and has therefore been the target of numerous ITS-related initiatives. However, there are few indications of actual working ITS solutions for dangerous goods. In this paper we conduct an empirical investigation of past projects and research to analyze the
Gas phase polyethylene reactors are able to produce several different grades of polymer. Adapting to market conditions requires grade transitions, associated with costs in terms of raw material and temporary production of lower priced off-specification products. In this paper, both stationary production and dynamic grade transitions are optimized to maximize profit, i.e., economic process optimiza
Background: Rectal washout (RW) is routinely performed during anterior resection (AR) for rectal cancer to reduce local recurrence (LR), although is sometimes not performed during minimally invasive surgery (MIS) procedures due to technical challenges and time consumption. The aim was to investigate the impact of RW on the oncological outcome after AR for rectal cancer in a registry cohort. Method
The fundamental importance of membrane proteins in drug discovery has meant that membrane mimetic systems for studying membrane proteins are of increasing interest. One such system has been the amphipathic, negatively charged poly(styrene-co-maleic acid) (SMA) polymer to form "SMA Lipid Particles" (SMALPs) which have been widely adopted to solubilize membrane proteins directly from the cell membra
The potential of geothermal energy for energy transition is increasingly recognized by governments around the world. Whether geothermal energy is a sustainable source of heat and/or electricity depends on how it is deployed in specific contexts. Therefore, it is striking that there is only limited attention to geothermal energy from a social science and humanities (SSH) perspective. Geothermal ene
Using different sources of human embryonic stem cells for research raises different ethical problems. Experimenting on embryos created for in vitro fertilization but left unused, or embryos, created specially for research raise ethical questions. In the first case – whether using “spare” human embryos for research means a lack of respect for the beginning of human life, and in the second – whether
A short wavelength approximation of a boundary integral operator for two-dimensional isotropic and homogeneous elastic bodies is derived from first principles starting from the Navier-Cauchy equation. Trace formulas for elastodynamics are deduced connecting the eigenfrequency spectrum of an elastic body to the set of periodic rays where mode conversion enters as a dynamical feature.
There are still divergent opinions regarding the pharmacodynamic effects of ketamine on the brain. In this study, the cerebral blood flow (CBF), cerebral metabolic rate for oxygen (CMRO2) and electroencephalographic (EEG) activity were sequentially assessed over 80 min in 17 normoventilated pigs following rapid i.v. infusions of anaesthetic (10.0 mg.kg-1; n = 7) or subanaesthetic (2.0 mg.kg-1; n =
BACKGROUND: The outcome after weaning from postcardiotomy venoarterial extracorporeal membrane oxygenation (VA-ECMO) is poor. In this study, we investigated the prognostic impact of arterial lactate levels at the time of weaning from postcardiotomy VA.METHODS: This analysis included 338 patients from the multicenter PC-ECMO registry with available data on arterial lactate levels at weaning from VA
The transcriptional mechanisms underlying tooth development are only beginning to be understood. Pitx2, a bicoid-like homeodomain transcription factor, is the first transcriptional marker observed during tooth development. Because Pitx2, Msx2, and Dlx2 are expressed in the dental epithelium, we examined the transcriptional activity of PITX2 in concert with Msx2 and the Dlx2 promoter. PITX2 activat
This article presents the results of survey-based research which explores if licensed aircraft maintenance engineers working in Norway, Sweden, and Portugal experience regulated “just culture” as procedural justice-infused processes when occurrence reporting in European Union (EU) civil aviation. Drawing on Tylerian procedural justice theory, the study finds that, perceived procedural justice is m
To obtain a global overview of how mitochondria respond to stress, we aimed to define the plant mitochondrial stress response (MSR). By combining a set of 1196 Arabidopsis thaliana genes that putatively encode mitochondrial proteins with 16 microarray experiments on stress-related conditions, 45 nuclear encoded genes were defined as widely stress-responsive. Using green fluorescent protein (GFP) f
Baker’s yeast, Saccharomyces cerevisiae, is a promising cell factory for the sustainable utilization of renewable resources for the formation of products with commercial value. Among these, poly-3-D-hydroxybutyrate (PHB) is an extensively studied biopolymer naturally accumulated in some bacteria and archaea species through the formation of carbon granules. Its bio-based origin, biodegradability an
Families living with mental illness express needs of support and experiences of burden that may affect their own health detrimentally and hence also their ability to support the patient. Mindfulness-based interventions have shown beneficial health effects in both clinical and healthy populations. The aim of the current study was to explore the effectiveness and usability of a web-based mindfulness
Introduction: the aim of this study was to identify whether factors beyond anatomical abnormalities are associated with low back pain (LBP) and LBP with sciatica (SCI) in older men. Material and methods: Mister Osteoporosis Sweden includes 3,014 men aged 69-81 years. They answered questionnaires on lifestyle and whether they had experienced LBP and SCI during the preceding 12 months. About 3,007 m
Aims and objectives: To explore healthcare professionals' conceptions of caring for sick children in home care services. Background: Families often prefer home care to hospital care, and the number of home care services for children is increasing. Caring for children at home has been recognised as challenging for healthcare professionals in home care services used to providing care predominately f
The duration of parental care in animals varies widely, from none to lifelong. Such variation is typically thought to represent a trade-off between growth and safety. Seabirds show wide variation in the age at which offspring leave the nest, making them ideal to test the idea that a trade-off between high energy gain at sea and high safety at the nest drives variation in departure age (Ydenberg’s
