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Motivation Machine learning offers a powerful approach for building predictive models from high-dimensional molecular data. Omics technologies such as transcriptomics, proteomics, and metabolomics quantify thousands of molecules simultaneously, providing deep insights into disease biology. Integrating multiple modalities can enhance predictive performance, as shown in histology-omics and holter-om
Integrating multi-modal patient data to support personalized medicine has gained a lot of interest across different health domains over the past decade. Addressing this challenge requires the development and implementation of an informed, evidence-based AI-driven decision-support system continuously maintained and updated to align with the latest clinical guidelines. A key challenge to ensure its
Abstract in UndeterminedNanoindentation has recently gained attention as a characterization technique for mechanical properties of biological tissues, such as bone, on the sub-micron level. However, optimal methods to characterize viscoelastic properties of bones are yet to be established. This study aimed to compare the time-dependent viscoelastic properties of bone tissue obtained with different
A number of techniques have been proposed to provide run- time performance guarantees while minimizing power consumption. One drawback of existing approaches is that they work only on a fixed set of components (or actuators) that must be specified at design time. If new components become available, these management systems must be redesigned and reimplemented. In this paper, we propose PTRADE, a n
There are many reasons why heat transfer and heat exchangers play a key role in the development of sustainable energy systems as well as in the reduction of emissions and pollutants. In general, all attempts to achieve processes and thermodynamic cycles with high efficiency, low emissions, low costs include heat transfer and heat exchangers to a large extent. It is known that sustainable energy de
Sustainable development rests on, among other things, the ability of policy to stimulate corporate actors to improve their environmental performance. Yet policy design and implementation is a challenging task in this area. This paper investigates this issue by examining the ability of the UK Emissions Trading Scheme to foster corporate sustainability from two perspectives: (a) its institutional fr
Recent critics of organizational learning and its normative offshoot the ‘learning organization’ have posited that conceptualisations of organizations based on knowledge and learning constitute a rhetorical device enabling elites to assert different forms of control through a new ‘normalising discourse’. The paper, whilst welcoming such critique, nevertheless asks whether it is adequate to dismiss
Popular Abstract in Swedish Det är en viktig uppgift för samhället att förebygga HIV och STI (sexuellt överförbara infektioner) bland ungdomar. Under de första åren av 1990-talet, när denna studie genomfördes, ökade dessa infektioner på ett oroväckande sätt. Detta gällde särskilt klamydiainfektionerna och nästan 25% av studenterna vid Lunds universitet rapporterade att de hade haft en konstaterad Slowing the incidence of HIV and STI among young people requires that they change their sexual behaviours. There is evidence that community-based interventions that target multiple levels of influence can be effective. In community mobilization different segments and sectors of a population are directly involved in problem identification and in the design and implementation of programs. The proces
In software engineering research, experiments are conducted to evaluate new methods or techniques. The experimentation as such is beginning to mature, but little effort is spent on learning across different studies, except for a few meta-analyses. Meta-analysis can be applied to a set of experiments with the same design. This paper discusses learning across a set of experimental studies on fault d
Bacterial surface-associated plasmin formation is believed to contribute to invasion, although the underlying molecular mechanisms are poorly understood. To define the components necessary for plasmin generation on group A streptococci we used strain AP53 which exposes an M-like protein ("PAM") that contains a plasminogen-binding sequence with two 13-amino acid residues long tandem repeats (a1 and
