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IGFBP1 and IGFBP3 polymorphisms predict circulating IGFBP-3 levels among women from high-risk breast cancer families.

The insulin-like growth factor (IGF) pathway has been implicated as risk modifier in premenopausal breast cancer. In this study, associations between single nucleotide polymorphisms (SNPs) and diplotypes in the IGFBP1 and IGFBP3 genes and circulating IGFBP-3 levels, BRCA family status and breast cancer among women from high-risk breast cancer families were investigated. Nine IGFBP1 and IGFBP3 SNPs

Neonicotinoid insecticide causes multigenerational impairment of inducible antipredator defenses in Daphnia

Nowadays organisms encounter not only natural challenges from predators but also significant anthropogenic stressors, such as insecticides, which can profoundly disrupt their normal growth and behavior. However, the knowledge on their potential interactions remains largely unknown, particularly regarding how insecticides may affect predator-prey interactions and prey responses across multiple gene

Organ Specific Killing af a Dispensable Organ or a Cell Population in an Organ - a Successful Design for Cancer Therapy - a Hypothesis

Purpose: This article hypothesizes that designing cancer therapies based on the organ specific toxicity of the normal tissue of the organ from which the tumors originated could be worthwhile. A prerequisite for successful therapy is that the individual can recover from damage done to the organ or cells.Results: Therapeutic examples are given for lymphoma, kidney cancer, melanoma and leukemia.Concl

Biogenic aerosol particles in the earth system model EC-earth

Treatments of emissions of primary biological aerosol particles (PBAP) were implemented in the global Earth System model EC-Earth. These emission schemes were improved to account for the strong peaks of PBAP concentrations in connection to precipitation events, which has been measured recently. The model is now able to treat the emission of bacteria, spores and pollen in dependency of precipitatio

Lipoprotein-associated phospholipase A2 activity, genetics and calcific aortic valve stenosis in humans

Background: Lipoprotein-associated phospholipase A2 (Lp-PLA2) activity has been shown to predict calcific aortic valve stenosis (CAVS) outcomes. Our objective was to test the association between plasma Lp-PLA2 activity and genetically elevated Lp-PLA2 mass/activity with CAVS in humans. Methods and results: Lp-PLA2 activity was measured in 890 patients undergoing cardiac surgery, including 476 pati

Association analysis identifies 65 new breast cancer risk loci

Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as BRCA1, and many common, mostly non-coding variants. However, much of the genetic contribution to breast cancer risk remains unknown. Here we report the results of a genome-wide association study of breast cancer in 122,977 cases and 105,974 controls of European ancestry and 14,068 cases and 13,104 controls of

Habits and self-assessed quality of life, negative intrusive thoughts and depressed mood in patients with prostate cancer : a longitudinal study

Objective: The aim of this study was to evaluate the association of self-assessed preoperative physical activity, alcohol consumption and smoking with self-assessed quality of life, negative intrusive thoughts and depressed mood after radical prostatectomy. Materials and methods: The Laparoscopic Prostatectomy Robot Open (LAPPRO) trial was a prospective, controlled, non-randomized longitudinal tri

Rapid multinodal acoustic trapping of extracellular vesicles for downstream mass spectrometry analysis

We report the use of multinodal acoustic trapping for high throughput and high capacity capturing of EV's (extracellular vesicles) for quantitative mass spectrometry analysis. The multinode trapping unit was shown to isolate sufficient amount of EV's from dilute biological samples (urine and cell culture supernatant) at flow rates of 500 ul/min within minutes, enabling EV proteome profiling. This

Mapping the melanoma plasma proteome (MPP) using single-shot proteomics interfaced with the WiMT database

Plasma analysis by mass spectrometry-based proteomics remains a challenge due to its large dynamic range of 10 orders in magnitude. We created a methodology for protein identification known as Wise MS Transfer (WiMT). Melanoma plasma samples from biobank archives were directly analyzed using simple sample preparation. WiMT is based on MS1 features between several MS runs together with custom prote

Övervakning av fåglarnas populationsutveckling: : Årsrapport för 2023

I denna rapport redovisas populationstrender för 224 svenska fågelarter för olika långa tidsperioder, samt korttidstrender för 13 arter av större däggdjur. Fåglarna har räknats höst, vinter, vår och sommar enligt strikt standardiserade metoder. Sommar- respektive vinterpunktrutter har räknats sedan 1975, i huvudsak i södra Sverige. Standardrutterna räknas också på sommaren (sedan 1996) men täcker We present the results of the Swedish Bird Survey, a project run by the Department of Biology, Lund University, as a part of the National Monitoring Programme of the Swedish Environmental Protection Agency. The results for 2023 include data from: 517 winter point counts in 2022/2023 (48th winter), of which 243 were carried out during the Christmas/New Year count, 181 summer point count routes (49t

Schlafen2 is a regulator of quiescence in adult murine hematopoietic stem cells

Even though hematopoietic stem cells (HSC) are characterized by their ability to self-renew and differentiate, they primarily reside in quiescence. Despite the immense importance of this quiescent state, its maintenance and regulation is still incompletely understood. Schlafen2 (Slfn2) is a cytoplasmic protein known to be involved in cell proliferation, differentiation, quiescence, interferon resp

Comorbidities in women with polycystic ovary syndrome : a sibling study

BACKGROUND: Polycystic ovary syndrome (PCOS) has previously been associated with several comorbidities that may have shared genetic, epigenetic, developmental or environmental origins. PCOS may be influenced by prenatal androgen excess, poor intrauterine or childhood environmental factors, childhood obesity and learned health risk behaviors. We analyzed the association between PCOS and several rel

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Compliance with (Quasi-) Judicial Decisions within the Regional African Human Rights System. Challenges and Opportunities Alejandro Fuentes Doctor of Law, Senior Researcher Patricia Iacob Research Assistant RESEARCH BRIEF Alejandro Fuentes Doctor of Law, Senior Researcher alejandro.fuentes@rwi.lu.se Patricia Iacob Research Assistant patricia.iacob@rwi.lu.se Disclaimer: The views and opinions expre

https://rwi.lu.se/app/uploads/2017/02/Compliancewithjudicialdecisions.pdf - 2026-05-31

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Compliance with (Quasi-) Judicial Decisions within the Regional African Human Rights System. Challenges and Opportunities Alejandro Fuentes Doctor of Law, Senior Researcher Patricia Iacob Research Assistant RESEARCH BRIEF Alejandro Fuentes Doctor of Law, Senior Researcher alejandro.fuentes@rwi.lu.se Patricia Iacob Research Assistant patricia.iacob@rwi.lu.se Disclaimer: The views and opinions expre

https://rwi.lu.se/wp-content/uploads/2017/02/Compliancewithjudicialdecisions_2017-02-10.pdf - 2026-05-31

SURVEILLE Archives - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law

SURVEILLE Archives - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Method

https://rwi.lu.se/tag/surveille/ - 2026-05-31

Cps-poster-07

AYA U R H AM M ER R EB EC K A H O LM ST RÖ M CLIFFO R D CH A R LES M A RTA G IL M A R IJA G R IN IU K U R SU LA B EC K SA N N A BL EN N O W N AN N A YLÖ N EN EXAM PROJECTS Critical & Pedagogical Studies 2019 AYA URHAMMER Counting On Biblioteket Rentemestervej, Copenhagen 10–16 April CLIFFORD CHARLES ‘A/part 8’ (apartheid) art activism & archive/s Tensta konsthall, Stockholm 9 April, 18:00 MARTA GI

https://www.khm.lu.se/en/sites/khm.lu.se.en/files/cps-poster-07.pdf - 2026-05-31

Annual report 2020 rsscb

Research School in Stem Cell Biology ANNUAL REPORT I 2020 2 QUOUSQUE TANDEM ABUTERE In brief The Research School in Stem Cell Biology is an academic consortium that focuses on excellence in research training and career development. We offer a diverse selection of educational activ- ities to provide the next generation of stem cell scientists with an excellent starting platform for a successful car

https://www.stemcellcenter.lu.se/sites/stemcellcenter.lu.se/files/annual_report_2020_rsscb.pdf - 2026-05-31

06032016 679 46 hadley am j gastroenterol 2015

HLA-DPB1*04:01 Protects Genetically Susceptible Children from Celiac Disease Autoimmunity in the TEDDY Study see related editorial on page x nature publishing group P E D IA T R IC S 915 © 2015 by the American College of Gastroenterology The American Journal of GASTROENTEROLOGY ORIGINAL CONTRIBUTIONS HLA-DPB1*04:01 Protects Genetically Susceptible Children from Celiac Disease Autoimmunity in t

https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_46_hadley_am_j_gastroenterol_2015.pdf - 2026-05-31