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PURPOSE: The design concept and the dosimetric characteristics of an applicator system for intraoperative radiation therapy (IORT) with special emphasis on alignment methods, the effect of a plastic scatterer in the beam, radiation leakage, and misalignment dosimetry, are presented in this paper. MATERIALS AND METHODS: A soft-docking system for a linear accelerator, which enables collimation of el
Background: Collagenous colitis is a chronic inflammatory bowel disease accompanied mainly by nonbloody diarrhea. The objectives of treatment are to alleviate the symptoms and minimize the deleterious effects on health-related quality of life (HRQOL). There is still no generally accepted clinical definition of remission or relapse. The purpose of this study was to analyze the impact of bowel sympt
Lumican and fibromodulin compete for collagen type I binding in vitro and fibromodulin-deficient mice have four-fold more lumican in tendons. These observations indicate that homologous sequences in lumican and fibromodulin bind to collagen type I. Here, we demonstrate that lumican binding to collagen type I is mediated mainly by Asp-213 in LRR 7. The mutation D213N in lumican impairs interaction
This study investigates utilization of the Internet in the rehabilitation of people on long-term sick leave with chronic pain and/or burnout. Fifty-five people were randomly assigned to two groups: a treatment group (n = 27) that participated in a rehabilitation course over the Internet and a waiting list group (n = 28). The goals were to improve participants' health and increase quality of life,
Objective: Cigarette smoking has been reported as "probable" risk factor for Amyotrophic Lateral Sclerosis (ALS), a poorly understood disease in terms of aetiology. The extensive longitudinal data of the European Prospective Investigation into Cancer and Nutrition (EPIC) were used to evaluate age-specific mortality rates from ALS and the role of cigarette smoking on the risk of dying from ALS. Met
This paper outlines how an understanding of the processes of building cognitive and sociopolitical legitimacy is relevant to the formation of a biorefining sector. First we describe a number of theoretical insights into challenges faced by emerging industries and how these can relate to the formation of a biorefining sector. Second, we present the conduct and results of an initial exploration of u
In this paper we address the problem of projective reconstruction of structure and motion given only image data. In particular we investigate three novel minimal combinations of points and lines over three views, and give complete solutions and reconstruction methods for two of these cases: "four points and three lines in three views", and "two points and six lines in three views". We show that in
Accurate measurement of bank risk is a matter of considerable importance for bank regulation and supervision. Current practices in most countries emphasize reliance on financial statement data for assessing banks’ risk. However, the possibility of increased reliance on market-based risk indicators has been a topic for academic and regulatory debate for a long time. Market monitoring of bank risk h
Current-mode control can be used to control switched DC-DC power converters. This paper compares two continuous-time models for current-mode control that are made to be accurate up to half the switching frequency. The two models are the ones presented by Ridley and Tan. The closed loop frequency responses predicted by these two models are compared with results obtained from simulations of a buck c
This paper presents new methods trellis source coding at rates above and below one. The new schemes have in common a code design based on branch correlation, a large reproducer alphabet, and an encoder based on either the Viterbi algorithm or a tailbiting MAP technique. The methods are easily adapted to various bit rates, but here only the results for R = 2 and R = 1/2 bits per source sample are p
Prepared under the framework of the European Cluster Alliance (ECA), the report provides an overview of existing good practice examples of different tools and analytical methods used during the cluster-making process. The report is based on the results of an international survey of experts working in the field, and the outcomes of a workshop organised in Copenhagen in September 2008. A number of
The latest long-term plan for science and technology reflects China’s determination both to overcome growing domestic social and environmental problems through technology and to become a world leader in innovation. This latest fifteen-year plan presents no radical departure from earlier strategies and continues to define policymaking by Beijing’s strong belief that innovation can be “decreed” top-
