Sökresultat

Ett flertal studier av svensk kommunal praktik pekar på betydelsen av att kommuner anpassar sig till förändrade förutsättningar (se till exempel Brorström och Siverbo 2008, Hellström med flera 2009). En del av dessa förändringar kan vara mer eller mindre tvingande, såsom förändringar i de lagar som omgärdar kommunal verksamhet, medan andra kan vara mer eller mindre frivilliga. Förändringar sker e

Normal sexual differentiation requires complex molecular events to take place in a precise order, and even though much knowledge has been gained in recent decades, further research is still needed to understand the pathogenesis of different disorders of sexual differentiation. For the clinician who is confronted with a child with sexual ambiguity, it is most important not to guess the sex but to i

Injuries and diseases of the hand naturally have an enormous impact on hand function and on quality of life, both occupational and social. The majority of hand-injury patients are under 30 years of age. Hand surgery, an established specialty in Sweden since 1969, is of great importance in terms of clinical developments, education and research. In the coming decade, scientific and clinical advances

This paper examines usage, function and meaning of the Swedish concept of ”otrygghet” (approx.: unsafety or insecurity) in political documents from two periods: 1970s and 2010s. Departing from a theoretical framework inspired by conceptual historian Reinhart Koselleck, this paper synchronically compares documents from Sweden’s two largest parties (Socialdemokraterna and Moderaterna), and diachroni

PURPOSE: The first interim analysis of the phase III, randomized, placebo-controlled TITAN study showed that apalutamide significantly improved overall survival (OS) and radiographic progression-free survival in patients with metastatic castration-sensitive prostate cancer (mCSPC) receiving ongoing androgen deprivation therapy (ADT). Herein, we report final efficacy and safety results after unblin

PURPOSE: To prospectively examine the association between clonal hematopoiesis (CH) and subsequent risk of lung cancer. METHODS: Among 200,629 UK Biobank (UKBB) participants with whole-exome sequencing, CH was identified in a nested case-control study of 832 incident lung cancer cases and 3,951 controls (2006-2019) matched on age and year at blood draw, sex, race, and smoking status. A similar nes

Background: Delayed cerebral ischemia (DCI), a complication of subarachnoid hemorrhage (SAH), is linked to cerebral vasospasm and associated with poor long-term outcome. We implemented a structured cerebral microdialysis (CMD) based protocol using the lactate/pyruvate ratio (LPR) as an indicator of the cerebral energy metabolic status in the neurocritical care decision making, using an LPR ≥ 30 as

We present a constructive approach to bounded l2-gain adaptive control with noisy measurements for linear time-invariant scalar systems with uncertain parameters belonging to a finite set. The gain bound refers to the closed-loop system, including the learning procedure. The approach is based on forward dynamic programming to construct a finite-dimensional information state consisting of H-infinit