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BACKGROUND AND OBJECTIVES: Degarelix is a gonadotropin-releasing hormone antagonist registered for the treatment of advanced hormone-dependent prostate cancer. Treatment causing androgen deprivation is associated with QT prolongation and this study investigated whether degarelix at supratherapeutic concentrations has an intrinsic effect per se on cardiac repolarisation and the QT interval.METHODS:

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Background : Currently, antiretroviral therapy (ART) is recommended for all HIV-positive patients with tuberculosis (TB). The timing of ART during the course of anti-TB treatment is based on CD4 cell counts. Access to CD4 cell testing is not universally available; this constitutes an obstacle for the provision of ART in low-income countries. Objective : To determine clinical variables associated w

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A search is presented for the direct pair production of a chargino and a neutralino [Formula: see text], where the chargino decays to the lightest neutralino and the [Formula: see text] boson, [Formula: see text], while the neutralino decays to the lightest neutralino and the 125 GeV Higgs boson, [Formula: see text]. The final states considered for the search have large missing transverse momentum

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China is a mega-diversity country with abundant natural resources, and the richness of these resources is demonstrated to be relevant with the local people’s historical interactions between biophysical and sociocultural systems. If we are to maintain biodiversity and strike a balance between human well-being and ecosystem service, it is important to incorporate the local people and their tradition

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In England saltmarshes account for less than 0.5% of the land area, however they have a very high biodiversity value and provide significant economic and social worth. Climate change, continuous coastal urbanisation, and port development are a serious concern for coastal protection planners, city councils and the government. It is a challenge for these decision makers to balance the social, econom

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A search for supersymmetry (SUSY) in events with large missing transverse momentum, jets, at least one hadronically decaying tau lepton and zero or one additional light leptons (electron/muon), has been performed using 20.3 fb(-1) of proton-proton collision data at root s = 8 TeV recorded with the ATLAS detector at the Large Hadron Collider. No excess above the Standard Model background expectatio

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Att härleda ett internationellt illegalt handlande till en viss stat och hålla denna ansvarig är ett komplext problem i folkrätten. Det oklara rättsläget kompliceras ytterligare när aspekter av cyberoperationer introduceras med den snabba globala teknologiska utvecklingen. Rättsläget som det ser ut just nu är baserat på doktrin och sekundärrätt, där vikt läggs vid den tekniska bevisningen för att Attributing internationally wrongful acts to a particular State and liability is a complex problem in international law. The already unclear legal situation is further complicated when aspects of cyber operations are introduced with the rapid global technological development. To hold a State liable for the actions of non-State actors in cyberspace, we can only use secondary law and doctrine. The l

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A search for heavy resonances decaying into a W or Z boson and a Higgs boson produced in proton-proton collisions at the Large Hadron Collider at s=13 TeV is presented. The analysis utilizes the dominant W→qq¯′ or Z→qq¯ and H→bb¯ decays with substructure techniques applied to large-radius jets. A sample corresponding to an integrated luminosity of 139 fb-1 collected with the ATLAS detector is anal

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Background: Traumatic brain injuries continue to be a significant cause of mortality and morbidity worldwide. Most traumatic brain injuries are classified as mild, with a low but not negligible risk of intracranial hemorrhage. To help physicians decide which patients might benefit from a computerized tomography (CT) of the head to rule out intracranial hemorrhage, several clinical decision rules h

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The need for modelling of materials behaviour under various mechanical conditions is driven by the evolution of computer capacity and the ability of scientists to address complex mechanical problems. Reliable models for materials behaviour, including accurate numerical values of parameters, are necessary for a continued beneficial development of the computational side of solid mechanics. High rate

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ObjectiveWe investigate the association between the geographic proximity of the grandparents on net marital fertility and maternal survival in Sweden, 1900–1910, within the framework of the cooperative-breeding-hypothesis.MethodsData were derived from Swedish full-count censuses (1880–1910) and the Swedish Death Index. Married couples were linked to their parental households. Poisson and logistic

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A search for new phenomena with top quark pairs in final states with one isolated electron or muon, multiple jets, and large missing transverse momentum is performed. Signal regions are designed to search for two-, three-, and four-body decays of the directly pair-produced supersymmetric partner of the top quark (stop). Additional signal regions are designed specifically to search for spin-0 media

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INTRODUCTION: Neurological complications after surgery for acute type A aortic dissection (ATAAD) increase patient morbidity and mortality. Carbon dioxide flooding is commonly used in open-heart surgery to reduce the risk of air embolism and neurological impairment, but it has not been evaluated in the setting of ATAAD surgery. This report describes the objectives and design of the CARTA trial, in

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Aims: To develop a suite of quality indicators (QIs) for the evaluation of the care and outcomes for adults with pulmonary arterial hypertension (PAH). Methods and results: We followed the European Society of Cardiology (ESC) methodology for the development of QIs. This included (i) the identification of key domains of care for the management of PAH, (ii) the proposal of candidate QIs following sy

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Purpose: The Extremely Preterm Infants in Sweden Study (EXPRESS) followed a national cohort of extremely preterm born (EPT, i.e. <27 weeks) children until 12 years of age. This study aimed to investigate the longitudinal development of visual acuity (VA) in children born EPT, explore the predictive value of early visual assessments, and evaluate risk factors for visual impairment at the age of 12

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A search for the nonresonant production of Higgs boson pairs in the Formula Presented channel is performed using Formula Presented of proton-proton collisions at a center-of-mass energy of 13 TeV recorded by the ATLAS detector at the CERN Large Hadron Collider. The analysis strategy is optimized to probe anomalous values of the Higgs boson self-coupling modifier Formula Presented and of the quarti

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Background: This study explored peer-led sex education for individuals with intellectual disabilities and/or autism (ID/ASD) from the perspective of project leaders within Swedish non-governmental organizations (NGOs). The purpose of this Grounded Theory study was to develop a conceptual model that characterizes the ways in which peer-led sex education is implemented by Swedish NGOs. This was done

Projektplan Campusutveckling 2024 2027 Till FS 240613

Campusutveckling vid Samhällsvetenskapliga fakulteten Uppdragsgivare: Dekan vid Samhällsvetenskapliga Fakulteten Lunds universitet Ansvarig i linjen för projektet: Kanslichef vid Samhällsvetenskapliga Fakulteten Lunds universitet Projektledare: Robert Holmberg Projekttid: Projektplanen revideras vid behov, dock senast 2027-06-30. ---------------------------------------------- Underskrift av uppdra

https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/2024-06/Projektplan%20Campusutveckling%202024_2027%20till%20FS%20240613.pdf - 2026-07-04